Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер unknown, С. 106647 - 106647
Опубликована: Янв. 1, 2025
Язык: Английский
Advanced Functional Materials, Год журнала: 2024, Номер 34(11)
Опубликована: Янв. 18, 2024
Abstract The practical application of hard carbon in sodium‐ion batteries is limited by insufficient reversible capacity and low initial Coulombic efficiency (ICE), which are caused the lack active sites unstable electrode/electrolyte interface. Herein, a biomass‐derived material based on tea stems proposed, exhibits an ultrahigh ICE 90.8%. This remarkable attributed to presence inorganic‐rich, thin, robust solid electrolyte interface (SEI) layer. Furthermore, demonstrates excellent cycling stability, showing retention 99.5% after 500 cycles at 280 mA g −1 . Additionally, when it works as anode full cell without presodiation, reaches high energy density 212 Wh kg superior e.g., retaining 93.1 mAh 1000 1 A with 91.3%. sodium storage this primarily combined adsorption‐intercalation/filling effect confirmed situ XRD ex Raman analyses. These findings make promising candidate for commercial batteries, achieving performance cost.
Язык: Английский
Процитировано
35
Advanced Science, Год журнала: 2024, Номер 11(30)
Опубликована: Июнь 14, 2024
Abstract In recent decades, research on Extracellular Vesicles (EVs) has gained prominence in the life sciences due to their critical roles both health and disease states, offering promising applications diagnosis, drug delivery, therapy. However, inherent heterogeneity complex origins pose significant challenges preparation, analysis, subsequent clinical application. This review is structured provide an overview of biogenesis, composition, various sources EVs, thereby laying groundwork for a detailed discussion contemporary techniques preparation analysis. Particular focus given state‐of‐the‐art technologies that employ microfluidic non‐microfluidic platforms EV processing. Furthermore, this discourse extends into innovative approaches incorporate artificial intelligence cutting‐edge electrochemical sensors, with particular emphasis single proposes current outlines prospective avenues future research. The objective motivate researchers innovate expand methods analysis fully unlocking biomedical potential.
Язык: Английский
Процитировано
27
Journal of Materials Chemistry B, Год журнала: 2024, Номер 12(9), С. 2236 - 2252
Опубликована: Янв. 1, 2024
Plant-derived exosomes (PDEs) show promising potential to be developed as a therapeutic agent against cancer, owing their multiple advantages such low toxicity, biocompatibility, availability, affordability, etc.
Язык: Английский
Процитировано
25
Nano-Micro Letters, Год журнала: 2024, Номер 16(1)
Опубликована: Март 21, 2024
Reactive oxygen species (ROS) plays important roles in living organisms. While ROS is a double-edged sword, which can eliminate drug-resistant bacteria, but excessive levels cause oxidative damage to cells. A core-shell nanozyme, CeO
Язык: Английский
Процитировано
21
Frontiers in Pharmacology, Год журнала: 2024, Номер 15
Опубликована: Март 7, 2024
Hyperuricemia (HUA), a severe metabolic disease derived from purine metabolism disorder, will lead to abnormally increased serum uric acid (SUA) levels in the body. Studies have shown that HUA is highly related gout, hypertension, diabetes, coronary heart disease, chronic kidney diseases, and so on. Traditional Chinese medicine (TCM) shows excellent results treating because of its unique advantages multi-metabolites multi-targets. This article reports on use TCM components for (UA)-lowering activity with efficacy low side effects based established models. work summarizes limitations various models evaluation. Applications treatment also been discussed detail. paper reveals recent research progress constructing evaluation systematic interventions. It provide scientific reference establishing model suggest future TCM-related studies.
Язык: Английский
Процитировано
17
Advanced Science, Год журнала: 2023, Номер 11(9)
Опубликована: Дек. 20, 2023
Abstract Treating the most widespread complication of diabetes: diabetic wounds poses a significant clinical obstacle due to intricate nature wound healing in individuals with diabetes. Here novel approach is proposed using easily applicable injectable gelatin/metal/tea polyphenol double nanonetworks, which effectively remodel microenvironment and accelerates process. The gelatin(Gel) crosslink metal ions (Zr 4+ ) through amino acids, imparting advantageous mechanical properties like self‐healing, injectability, adhesion. nanonetwork's biological functions are further enhanced by incorporating tea nanonetwork situ doping epigallocatechin gallate (EGCG) great antibacterial, antioxidant, anticancer capabilities. vitro vivo tests show that this nanonetworks hydrogel exhibits faster cell migration favorable anti‐inflammatory antioxidant can greatly reshape accelerate rate. In addition, completely degraded after subcutaneous injection for 7 d ays , nondetectable cytotoxicity H&E staining major mice organs serum level liver function indicators. Considering above‐mentioned merits hydrogel, it believed have broad biomedical potential, especially repair tissue engineering.
Язык: Английский
Процитировано
40
Nanoscale Advances, Год журнала: 2024, Номер unknown
Опубликована: Янв. 1, 2024
Key challenges in exosomal based therapies.
Язык: Английский
Процитировано
15
Theranostics, Год журнала: 2024, Номер 14(12), С. 4598 - 4621
Опубликована: Янв. 1, 2024
Over the past ten years, significant advancements have been made in exploring plant-derived exosome-like nanoparticles (PELNs) for disease therapeutics and drug delivery. PELNs, as inherent nanoscale particles comprised of proteins, lipids, nucleic acids, secondary metabolites, exhibit capacity cellular uptake by human cells. This intercellular interaction transcends biological boundaries, effectively influencing functions animals. PELNs outstanding biocompatibility, low immunogenicity, enhanced safety, environmentally friendly sustainability. article summarized preparation methods characteristics PELNs. It provided a systematic review varied roles derived from fruits, vegetables, herbs The challenges their production application were discussed, future prospects this rapidly evolving field explored.
Язык: Английский
Процитировано
14
ACS Nano, Год журнала: 2024, Номер 18(6), С. 4862 - 4870
Опубликована: Янв. 17, 2024
Frequent outbreaks of viral diseases have brought substantial negative impacts on society and the economy, they are very difficult to detect, as concentration aerosols in air is low composition complex. The traditional detection method manually collection re-detection, being cumbersome time-consuming. Here we propose a virus aerosol based microfluidic inertial separation spectroscopic analysis technology rapidly accurately detect particles air. chip designed principles laminar flow characteristics, resulting an average efficiency 95.99% for 2 μm particles. We build composite spectrometer platform capture spectral information dynamically. By employing machine-learning techniques, can classify different types entire experiment took less than 30 min compared with hours by PCR detection. Furthermore, our model achieves accuracy 97.87% identifying aerosols, which comparable results obtained from
Язык: Английский
Процитировано
9
Journal of Nanobiotechnology, Год журнала: 2024, Номер 22(1)
Опубликована: Апрель 1, 2024
Abstract Background Herbal nanoparticles are made from natural herbs/medicinal plants, their extracts, or a combination with other nanoparticle carriers. Compared to traditional herbs, herbal lead improved bioavailability, enhanced stability, and reduced toxicity. Previous research indicates that medicine nanomaterials rapidly advancing making significant progress; however, bibliometric analysis knowledge mapping for currently lacking. We performed by retrieving publications related the Web of Science Core Collection (WoSCC) database spanning 2004 2023. Data processing was using R package Bibliometrix, VOSviewers, CiteSpace. Results In total, 1876 articles were identified, originating various countries, China being primary contributing country. The number in this field increases annually. Beijing University Chinese Medicine, Shanghai Traditional Saveetha India prominent institutions domain. Journal “International Nanomedicine” has highest publications. authors these reached 8234, Yan Zhao, Yue Zhang, Huihua Qu most prolific Zhao frequently cited author. “Traditional medicine,” “drug delivery,” “green synthesis” main focal points. Themes such as synthesis,” “curcumin,” “wound healing,” “carbon dots” may represent emerging areas. Conclusions Our study findings assist identifying latest frontiers hot topics, providing valuable references scholars investigating role nanotechnology medicine. Graphical
Язык: Английский
Процитировано
9