Effectiveness of Different Intervention Modes in Lifestyle Intervention for the Prevention of Type 2 Diabetes and the Reversion to Normoglycemia in Adults With Prediabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Journal of Medical Internet Research, Год журнала: 2025, Номер 27, С. e63975 - e63975

Опубликована: Янв. 29, 2025

Lifestyle interventions have been acknowledged as effective strategies for preventing type 2 diabetes mellitus (T2DM). However, the accessibility of conventional face-to-face is often limited. Digital health intervention has suggested a potential solution to overcome limitation. Despite this, there remains significant gap in understanding effectiveness digital individuals with prediabetes, particularly reducing T2DM incidence and reverting normoglycemia. This study aimed assess different modes health, face-to-face, blended interventions, benefits intervention, facilitating reversion normoglycemia adults prediabetes compared usual care. We conducted comprehensive search 9 electronic databases, namely MEDLINE, Embase, ACP Journal Club, Cochrane Central Register Controlled Trials, Database Systematic Reviews, Clinical Answers, Methodology Register, Health Technology Assessment, NHS Economic Evaluation through Ovid, from inception October 2024. review included randomized controlled trials (RCTs) that studied lifestyle prediabetes. The overall effect was synthesized using random-effects model. I² statistic used heterogeneity across RCTs. performed subgroup analysis explore control group, which received From an initial 7868 records retrieved we identified 54 articles 31 Our showed demonstrated 46% risk reduction (risk ratio [RR] 0.54, 95% CI 0.47-0.63; I²=43%; P<.001), increase (RR 1.46, 1.11-1.91; I²=82%; P=.006), when group. On other hand, were associated 12% 0.88, 0.77-1.01; I²=0.6%; P=.06). Moreover, combining 37% 0.63, 0.49-0.81;I²<0.01%; P<.001) 87% 1.87, 1.30-2.69; I²=23%; P=.001). no on reversal observed interventions. Face-to-face consistently promising both reductions these areas not sufficiently proven. Given results, further research required provide more definitive evidence prevention future. PROSPERO CRD42023414313; https://tinyurl.com/55ac4j4n.

Язык: Английский

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Psychological and Clinical Challenges in the Management of Type 1 Diabetes during Adolescence: A Narrative Review

Children, Год журнала: 2024, Номер 11(9), С. 1085 - 1085

Опубликована: Сен. 4, 2024

Adolescence, a critical period of physical and psychological development, presents unique challenges in type 1 diabetes (T1D) management due to endocrinological changes, reduced therapeutic adherence, elevated susceptibility issues such as depression, anxiety, eating disorders. This narrative review explores the impact behavioral factors on glycemic control adolescents with T1D. We examine prevalence influence mental health disorders, lifestyle factors, harmful behaviors, social dynamics outcomes. Strategies for improving metabolic are also reviewed, including cognitive therapy, technological devices, educational interventions. The importance tailored support, family involvement, targeted interventions improve adherence treatment T1D should be emphasized.

Язык: Английский

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Diabetes and obesity: the role of stress in the development of cancer

Endocrine, Год журнала: 2024, Номер unknown

Опубликована: Июнь 3, 2024

Abstract Diabesity is a condition where an individual has both diabetes and obesity, which can lead to severe complications including cardiovascular disease, leading cause of mortality. Recently, cancer become excess hospitalizations, obesity are associated with higher risk developing several types cancer. In this review, we propose that chronic stress significantly increases association. Managing challenging as they significant distress. The relationship between interconnected, anxiety depression being common in patients. Cancer diagnosis treatment lasting changes the body’s neuroendocrine system, causing excessive release catecholamines prostaglandins patients undergoing surgery, promotes spread other parts body. Furthermore, could increase diabetes, or both.

Язык: Английский

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Pre-Type 1 Diabetes in Adolescents and Teens: Screening, Nutritional Interventions, Beta-Cell Preservation, and Psychosocial Impacts

Journal of Clinical Medicine, Год журнала: 2025, Номер 14(2), С. 383 - 383

Опубликована: Янв. 9, 2025

Type 1 Diabetes (T1D) is a progressive autoimmune disease often identified in childhood or adolescence, with early stages detectable through pre-diabetic markers such as autoantibodies and subclinical beta-cell dysfunction. The identification of the pre-T1D stage critical for preventing complications, diabetic ketoacidosis, enabling timely interventions that may alter progression. This review examines multifaceted approach to managing T1D risk adolescents teens, emphasizing detection, nutritional interventions, preservation strategies, psychosocial support. Screening T1D-associated offers predictive insight into risk, particularly when combined education family resources promote lifestyle adjustments. Although alone are not capable T1D, certain weight management specific choices, have shown potential preserve insulin sensitivity, reduce inflammation, mitigate metabolic strain. Pharmacological including immune-modulating drugs like teplizumab, alongside emerging regenerative cell-based therapies, offer delay onset by protecting function. social psychological impacts diagnosis also significant, affecting adolescents' quality life, dynamics, mental health. Supportive counseling, cognitive-behavioral therapy (CBT), group support, recommended emotional burden pre-diabetes. Future directions call integrating universal targeted screening programs within schools primary care, advancing research nutrition promoting policies enhance access preventive resources. Advocacy insurance coverage screening, health services crucial support families risk. By addressing these areas, healthcare systems can intervention, improve preservation, overall well-being at T1D.

Язык: Английский

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The Interconnected Complexity of Diabetes and Depression

Diabetes Spectrum, Год журнала: 2025, Номер 38(1), С. 23 - 31

Опубликована: Фев. 1, 2025

Diabetes and depression have a bidirectional relationship, with negative impacts on glycemia, self-care, long-term complications, quality of life, mortality. This review highlights key aspects the interconnected complex relationship between diabetes depression, including how it affects health outcomes, duration recurrence, age-specific manifestations, recommendations for screening nonpharmacological treatment.

Язык: Английский

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Diabetes Management in Detention Facilities: A Statement of the American Diabetes Association

Diabetes Care, Год журнала: 2024, Номер 47(4), С. 544 - 555

Опубликована: Март 25, 2024

This statement provides guidance for diabetes care in detention facilities. It focuses on areas where the processes delivery of to people with facilities may differ from those community, and key points are made at end each section. Areas emphasis, which inform multiple aspects discussed this statement, include 1) timely identification or diagnosis treatment needs continuity (at reception/intake, during transfers, upon discharge), 2) nutrition physical activity, 3) access management tools (insulin, blood glucose monitoring, tracking data, current technologies, etc.), 4) whole person (self-management education, mental health support, monitoring addressing long-term complications, specialty care, etc.).

Язык: Английский

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Type 2 Diabetes

Annals of Internal Medicine, Год журнала: 2024, Номер 177(6), С. ITC81 - ITC96

Опубликована: Июнь 1, 2024

Type 2 diabetes (T2D) is a prevalent disease that increases risk for vascular, renal, and neurologic complications. Prevention treatment of T2D its complications are paramount. Many advancements in care have emerged over the past 5 years, including increased understanding importance early intensive glycemic control, mental health, social determinants healthy eating patterns, continuous glucose monitoring, benefits some drugs preventing cardiorenal disease. This review summarizes evidence supporting prevention treatment, focusing on aspects commonly purview primary physicians.

Язык: Английский

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Hypoglycemia knowledge assessment tool — Development and validation of the Hypoglycemia Management Knowledge Scale in Taiwan

Applied Nursing Research, Год журнала: 2025, Номер unknown, С. 151916 - 151916

Опубликована: Янв. 1, 2025

Язык: Английский

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Effects of exercise training and physical activity advice on HbA1c in people with type 2 diabetes: A network meta-analysis of randomized controlled trials

Diabetes Research and Clinical Practice, Год журнала: 2025, Номер unknown, С. 112027 - 112027

Опубликована: Фев. 1, 2025

Язык: Английский

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The influence of cyclothymic and hyperthymic affective temperaments on glycemic control in patients with type 2 diabetes

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Фев. 18, 2025

Abstract Affective temperaments are inherited parts of personality determining mood and activity, affecting the management somatic conditions. We aimed to investigate association between affective temperaments, depressive symptoms, self-care (physical smoking, alcohol consumption), their effect on glycemic control, among patients with type 2 diabetes (T2DM) in general practice, a cross-sectional study enrolling 338 consecutive from six primary care practices Hungary. A self-administered questionnaire (history, anthropometric, socioeconomic, laboratory parameters), Beck Depression Inventory (BDI), Hamilton Anxiety Scale, Temperament Evaluation Memphis, Pisa, Paris, San Diego Autoquestionnaire were used. Cyclothymic temperament determined HbA1c levels regression analysis ( p = 0.002), BDI score 0.048). In causal mediation analyses, cyclothymic was directly associated higher 0.008). Hyperthymic indirectly lower HbA1c, mediated by 0.034). Depressive, anxious, irritable lifestyle factors not neither nor as direct or mediating factors. Among T2DM, correlates worse independently symptoms. reduces thereby improving control. Identifying may improve care.

Язык: Английский

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