Cellulose, Год журнала: 2025, Номер unknown
Опубликована: Март 11, 2025
Язык: Английский
Exploration, Год журнала: 2024, Номер 4(3)
Опубликована: Янв. 17, 2024
Abstract Reactive oxygen species play a crucial role in cell signaling pathways during wound healing phases. Treatment strategies to balance the redox level deep tissue are emerging for management. In recent years, reactive scavenging agents including natural antioxidants, (ROS) nanozymes, and antioxidant delivery systems have been widely employed inhibit oxidative stress promote skin regeneration. Here, importance of different phases is critically analyzed. Various cutting‐edge bioactive ROS nanoscavengers platforms discussed. This review also highlights future directions therapies via scavenging. comprehensive offers map research on scavengers with balancing mechanisms action process, which benefits development clinical applications next‐generation scavenging‐based nanomaterials
Язык: Английский
Процитировано
59
Pharmaceutics, Год журнала: 2024, Номер 16(3), С. 300 - 300
Опубликована: Фев. 21, 2024
Wounds, which are becoming more common as a result of traumas, surgery, burns, and chronic illnesses like diabetes, remain critical medical problem. Infectious bacteria impact the healing process, particularly if its biofilm (biological films) leads to prolonged effect. Nanomaterials have emerged promising candidates in field wound due their unique properties versatile applications. New insights into interactions between nanomaterials microenvironments shed light on mechanisms underlying therapeutic effects. However, significantly minimal amount research has been carried out see these promote process. In this review, we provided an outline various types that studied for wounds infection prevention. Overall, utilization holds great promise continues evolve, providing new opportunities development effective efficient care therapies.
Язык: Английский
Процитировано
23
Gels, Год журнала: 2024, Номер 10(3), С. 175 - 175
Опубликована: Фев. 29, 2024
The management of wound healing represents a significant clinical challenge due to the complicated processes involved. Chitosan has remarkable properties that effectively prevent certain microorganisms from entering body and positively influence both red blood cell aggregation platelet adhesion in bloodstream, resulting favorable hemostatic outcome. In recent years, chitosan-based hydrogels have been widely used as dressings their biodegradability, biocompatibility, safety, non-toxicity, bioadhesiveness, soft texture resembling extracellular matrix. This article first summarizes an overview main chemical modifications chitosan for then reviews desired hydrogel dressings. applications healing, including burn wounds, surgical infected diabetic wounds are discussed. Finally, future prospects It is anticipated this review will form basis development range treatment.
Язык: Английский
Процитировано
18
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 261, С. 129665 - 129665
Опубликована: Янв. 23, 2024
Язык: Английский
Процитировано
12
Chemical Engineering Journal, Год журнала: 2024, Номер 497, С. 155033 - 155033
Опубликована: Авг. 23, 2024
Язык: Английский
Процитировано
8
International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 139745 - 139745
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
1
Nanoscale Advances, Год журнала: 2024, Номер 6(14), С. 3513 - 3532
Опубликована: Янв. 1, 2024
Recent advancements in MXene-based wound dressings are discussed, focusing on their contributions to tissue regeneration, infection control, anti-inflammation and photothermal effects, targeted therapeutic delivery.
Язык: Английский
Процитировано
7
Stem Cell Research & Therapy, Год журнала: 2024, Номер 15(1)
Опубликована: Ноя. 9, 2024
Since wound healing is one of the most important medical challenges and common dressings have not been able to manage this challenge well today, efforts increased achieve an advanced dressing. Mesenchymal stem cells exosomes derived from them shown high potential in regenerating wounds due their immunomodulatory, anti-inflammatory, immunosuppressive, regenerative capacities. However, such as short life these cells, low durability area, stability resulted limitations use for healing. Nowadays, different scaffolds are considered suitable biomaterials These made natural or synthetic polymers promising ideal dressing that does disadvantages dressings. One strategies has attracted much attention today using seeding delivering MSCs exosomes. This combined strategy a enhancing shelf increasing In review, combination with comprehensively discussed.
Язык: Английский
Процитировано
5
Journal of Functional Biomaterials, Год журнала: 2023, Номер 14(7), С. 352 - 352
Опубликована: Июль 4, 2023
The field of biomedical engineering highly demands technological improvements to allow the successful engraftment biomaterials requested for healing damaged host tissues, tissue regeneration, and drug delivery. Polymeric materials, particularly natural polymers, are one primary suitable materials employed functionalized enhance their biocompatibility thus confer advantageous features after graft implantation. Incorporating bioactive substances from nature is a good technique expanding or increasing functionality biomaterial scaffolds, which may additionally encourage healing. Our ecosystem provides resources, like honeybee products, comprising rich blend phytochemicals with interesting properties, which, when functionally coupled biomaterials, result in exhibiting anti-inflammatory, antimicrobial, antioxidant effects. Bee pollen sustainable product recently discovered as new functionalizing agent biomaterials. This review aims articulate general idea using products engineering, mainly focusing on describing recent literature experimental studies bee pollen. We have also described underlying mechanism attributes shared our perspective how future research will benefit fabrication such
Язык: Английский
Процитировано
12
Gels, Год журнала: 2023, Номер 9(10), С. 791 - 791
Опубликована: Окт. 1, 2023
In this study, hesperidin was loaded into a transethosome and developed employing the rotary evaporator method. The formulation optimized using Box–Behnken design (BBD). HSD-TE has spherical shape, vesicle size, polydispersity index, entrapment efficiency, zeta potential within range of 178.98 nm; PDI 0.259 with −31.14 mV % EE 89.51%, respectively. in vitro drug release shows that exhibited 81.124 ± 3.45% comparison to HSD suspension. ex vivo skin permeation showed 2-fold increase gel permeation. antioxidant activity found be 79.20 1.77% higher than solution. deeper penetration across excised rat membranes confocal laser microscopy scanning, indicating promising prospects. dermatokinetic compared conventional where TE significantly boosted transport epidermis dermal layers. greater efficacy free inhibition microbial growth, as evidenced by antibacterial on Gram-negative positive bacteria. These investigations could enhance topical application management cutaneous bacterial infections.
Язык: Английский
Процитировано
12