Recent advances in cellulose- and alginate-based hydrogels for water and wastewater treatment: A review

Carbohydrate Polymers, Год журнала: 2023, Номер 323, С. 121339 - 121339

Опубликована: Сен. 1, 2023

Язык: Английский

---

Polysaccharide-based tumor microenvironment-responsive drug delivery systems for cancer therapy

Journal of Controlled Release, Год журнала: 2023, Номер 362, С. 19 - 43

Опубликована: Авг. 24, 2023

Язык: Английский

---

Nano-hydroxyapatite (nHAp) scaffolds for bone regeneration: Preparation, characterization and biological applications

Journal of Drug Delivery Science and Technology, Год журнала: 2024, Номер 95, С. 105601 - 105601

Опубликована: Март 18, 2024

Язык: Английский

---

Alginate-Based Encapsulation Fabrication Technique for Drug Delivery: An Updated Review of Particle Type, Formulation Technique, Pharmaceutical Ingredient, and Targeted Delivery System

Pharmaceutics, Год журнала: 2024, Номер 16(3), С. 370 - 370

Опубликована: Март 6, 2024

Alginate is a natural biopolymer widely studied for pharmaceutical applications due to its biocompatibility, low toxicity, and mild gelation abilities. This review summarizes recent advances in alginate-based encapsulation systems targeted drug delivery. formulations like microparticles, nanoparticles, microgels, composites fabricated by methods including ionic gelation, emulsification, spray drying, freeze drying enable tailored loading, enhanced stability, sustained release kinetics. microspheres prepared or provide gastric protection colon-targeted of orally delivered drugs. nanoparticles exhibit cellular uptake tumor-targeting capabilities through the permeation retention effect. Crosslinked alginate microgels allow high loading controlled profiles. Composite gels with cellulose, chitosan, inorganic nanomaterials display improved mechanical properties, mucoadhesion, tunable Alginate-based wound dressings containing antimicrobial promote healing burns chronic wounds topical Although well-established as excipient, more extensive vivo testing needed assess clinical safety efficacy emerging prior human trials. Future opportunities include engineered combining stimuli-responsiveness, active targeting, diagnostic capabilities. In summary, this discusses techniques oral, transdermal, intravenous delivery, an emphasis on approaches enabling therapeutic outcomes.

Язык: Английский

---

Biodegradable Natural Hydrogels for Tissue Engineering, Controlled Release, and Soil Remediation

Polymers, Год журнала: 2024, Номер 16(18), С. 2599 - 2599

Опубликована: Сен. 14, 2024

This article provides insights into hydrogels of the most promising biodegradable natural polymers and their mechanisms degradation, highlighting different possibilities controlling hydrogel degradation rates. Since can be designed as scaffolding materials to mimic physical biochemical properties tissues, these have found widespread application in field tissue engineering controlled release. In same manner, potential water reservoirs, macro- microelement carriers, or matrixes for selective adsorption pollutants make them excellent candidates sustainable soil amendment solutions. Accordingly, this summarizes recent advances fields engineering, release, remediation, emphasizing new opportunities that degradability its tunability offer design applicability hydrogels.

Язык: Английский

---

3D Printing of Polysaccharide-Based Hydrogel Scaffolds for Tissue Engineering Applications: A Review

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 270, С. 132123 - 132123

Опубликована: Май 17, 2024

Язык: Английский

---

Bone Regeneration: A Review of Current Treatment Strategies

Journal of Clinical Medicine, Год журнала: 2025, Номер 14(6), С. 1838 - 1838

Опубликована: Март 8, 2025

Bone regeneration has emerged as a critical research and clinical advancement field, fueled by the growing demand for effective treatments in orthopedics oncology. Over past two decades, significant progress biomaterials surgical techniques led to development of novel solutions treating bone defects, surpassing use traditional autologous grafts. This review aims assess latest approaches regeneration, including autologous, allogenic, xenogenic grafts, naturally derived biomaterials, innovative synthetic substitutes such bioceramics, bioactive glasses, metals, polymers, composite materials, other specialized applications. A comprehensive literature search was conducted on PubMed, focusing studies published between 2019 2024, meta-analyses, reviews, systematic reviews. The evaluated range strategies, examining outcomes, materials used, techniques, effectiveness various defects. identified numerous studies, with inclusion criteria focused those exploring strategies. These provided valuable insights into biological outcomes different graft types. Results indicated that while advancements show promising potential, challenges remain optimizing therapeutic strategies across diverse patient populations settings. findings emphasize need an integrated approach combines scientific research, practice, technological innovation improve therapies. Further is required establish standardized protocols determine optimal application enhance quality care.

Язык: Английский

---

Hydrogels for Wound Dressings: Applications in Burn Treatment and Chronic Wound Care

Journal of Composites Science, Год журнала: 2025, Номер 9(3), С. 133 - 133

Опубликована: Март 13, 2025

Severe skin injuries such as burns and chronic wounds are a subject of interest in the medical field, they require much attention. These types susceptible to serious complications, which can worsen health patients reduce their quality life. Hydrogels have emerged innovative wound dressings for treating acute wounds, including burns, diabetic foot ulcers, venous leg pressure ulcers. polymeric networks provide moist environment, promote cellular migration, offer antimicrobial properties, being recognized superior conventional dressings. This review aims explore recent advancements hydrogel-based dressings, emphasizing state-of-the-art technologies used this purpose trend achieving personalized therapeutic approaches. Despite promising vitro vivo findings described review, further clinical validation large-scale manufacturing optimizations required widespread adoption.

Язык: Английский

---

Development of Biocompatible 3D-Printed Artificial Blood Vessels through Multidimensional Approaches

Journal of Functional Biomaterials, Год журнала: 2023, Номер 14(10), С. 497 - 497

Опубликована: Окт. 8, 2023

Within the human body, intricate network of blood vessels plays a pivotal role in transporting nutrients and oxygen maintaining homeostasis. Bioprinting is an innovative technology with potential to revolutionize this field by constructing complex multicellular structures. This technique offers advantage depositing individual cells, growth factors, biochemical signals, thereby facilitating functional vessels. Despite challenges fabricating vascularized constructs, bioprinting has emerged as advance organ engineering. The continuous evolution biomaterial knowledge provides avenue overcome hurdles associated tissue fabrication. article overview biofabrication process used create vascular constructs. It delves into various techniques engineering, including extrusion-, droplet-, laser-based methods. Integrating these prospect crafting artificial remarkable precision functionality. Therefore, impact engineering significant. With technological advances, it holds promise revolutionizing transplantation, regenerative medicine. By mimicking natural complexity vessels, brings us one step closer organs vasculature, ushering new era medical advancement.

Язык: Английский

---

A ternary composite hydrogel based on sodium alginate, carboxymethyl cellulose and copper-doped 58S bioactive glass promotes cutaneous wound healing in vitro and in vivo

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 259, С. 129260 - 129260

Опубликована: Янв. 8, 2024

Язык: Английский

---