Archives of Gerontology and Geriatrics Plus,
Год журнала:
2023,
Номер
1(1), С. 100003 - 100003
Опубликована: Дек. 25, 2023
Aging
is
a
complex
journey
shaped
by
interactions
among
mechanisms,
biochemistry,
physiology,
and
social
habits.
This
review
explores
aging's
core
facets
uncovering
the
mechanisms
driving
cellular
senescence,
oxidative
stress,
telomere
shortening,
mitochondrial
dysfunction.
The
also
delves
into
biochemistry
physiology
of
aging,
shedding
light
on
hormonal
shifts,
genetic
influences,
immune
system
modifications
that
contribute
to
aging
process.
It
navigates
terrain
habits
linked
considering
profound
impact
dietary
choices,
physical
activity,
engagement,
stress
management.
These
elements
intricately
intertwine,
emphasizing
holistic
nature
aging.
interplay
between
underscores
need
for
comprehensive
understanding
transcends
single
disciplines.
Deciphering
these
factors
significance
personalized
approaches
healthy
Tailoring
interventions
individual
genetics,
lifestyles,
health
needs
emerges
as
critical
strategy
optimizing
well-being
in
later
life.
In
conclusion,
this
illuminates
multifaceted
urging
embrace
complexity
interdependence.
By
fostering
holistic,
approach,
individuals
can
navigate
with
grace,
vitality,
resilience.
Nutrients,
Год журнала:
2020,
Номер
12(8), С. 2324 - 2324
Опубликована: Авг. 3, 2020
The
present
study
aimed
to
identify
patterns
of
dietary
changes
during
the
COVID-19
pandemic
and
their
associations
with
sociodemographics,
body
mass
index
(BMI)
before
pandemic,
lifestyle
in
Polish
adults
examine
effects
lockdowns
on
dietary–lifestyle
changes.
This
used
a
cross-sectional
online
survey
collect
data.
k-means
algorithm
was
determine
changes,
logistic
regression
analyses
were
performed.
During
period,
43%
respondents
decreased
physical
activity
(PA),
49%—increased
screen
time,
34%—increased
food
consumption.
Among
three
patterns,
two
opposite
found:
Prohealthy
(28%
participants)
Unhealthy
(19%
participants).The
adherence
pattern
negatively
associated
age,
but
positively
being
overweight
(aOR
1.31)
or
obese
1.64).
Residing
macroeconomic
region
GDP
>
100%
0.73)
increased
1.47).
Adults
over
40
years
old,
those
living
children,
unemployed,
higher
GDP,
not
consuming
homemade
meals
could
be
more
exposed
unhealthy
behaviors.
From
public
health
perspective,
enhancing
message
“to
active”
compulsory
isolation
period
should
prioritized.
Psychology Research and Behavior Management,
Год журнала:
2020,
Номер
Volume 13, С. 797 - 811
Опубликована: Сен. 1, 2020
The
purpose
of
this
study
is
to
examine
the
association
anxiety
with
self-rated
general
health,
satisfaction
life,
stress
and
coping
strategies
university
students
during
COVID-19
pandemic
outbreak
in
Poland.A
total
914
students,
ranged
age
between
18
40
years
old
(M
=
23.04,
SD
2.60),
participated
an
online
survey.
was
performed
30
March
April
2020,
coronavirus
quarantine.
Participants
completed
a
standard
psychological
questionnaire,
including
General
Anxiety
Disorder
(GAD-7),
Self-Rated
Health
(GSRH),
Satisfaction
With
Life
Scale
(SWLS),
Perceived
Stress
(PSS),
Coping
Inventory
for
Stressful
Situations
(CISS).The
majority
(65%)
showed
mild
severe
GAD
high
level
perceived
(56%).
Those
who
had
worst
evaluated
current
GSRH,
comparison
situation
before
outbreak,
also
demonstrated
higher
levels
anxiety,
stress,
emotion-oriented
styles.
indicates
that
variance
may
be
explained
about
60%
by
such
variables,
like
low
female
gender,
frequent
use
both
task-oriented
styles.University
experience
extremely
quarantine
period
they
need
professional
help
cope
pandemic.
results
prepare
appropriate
future
intervention
effective
prevention
programs
at
universities.
Nutrition Reviews,
Год журнала:
2020,
Номер
79(4), С. 382 - 393
Опубликована: Июнь 10, 2020
Abstract
Optimal
nutrition
can
improve
well-being
and
might
mitigate
the
risk
morbidity
associated
with
coronavirus
disease
2019
(COVID-19),
caused
by
severe
acute
respiratory
syndrome
2
(SARS-CoV-2).
This
review
summarizes
nutritional
guidelines
to
support
dietary
counseling
provided
dietitians
health-related
professionals.
The
majority
of
documents
encouraged
consumption
fruits,
vegetables,
whole
grain
foods.
Thirty-one
percent
highlighted
importance
minerals
vitamins
such
as
zinc
C,
A,
D
maintain
a
well-functioning
immune
system.
Dietary
supplementation
has
not
been
linked
COVID-19
prevention.
However,
C
D,
well
selenium,
was
potentially
beneficial
for
individuals
with,
or
at
of,
viral
infections
those
in
whom
nutrient
deficiency
is
detected.
There
no
convincing
evidence
that
food
packaging
transmission
COVID-19,
but
good
hygiene
practices
handling
preparing
foods
were
recommended.
No
changes
breastfeeding
recommendations
have
made,
even
women
diagnosed
COVID-19.
Frontiers in Immunology,
Год журнала:
2020,
Номер
11
Опубликована: Авг. 7, 2020
Elderly
individuals
are
the
most
susceptible
to
an
aggressive
form
of
coronavirus
disease
(COVID-19)
mediated
by
SARS-CoV-2.
The
remodeling
immune
response
that
is
observed
among
elderly
could
explain,
at
least
in
part,
age
gradient
lethality
COVID-19.
In
this
review,
we
will
discuss
phenomenon
immunosenescence,
which
entails
changes
occur
both
innate
and
adaptive
immunity
with
aging.
Furthermore,
inflamm-aging,
a
low-grade
inflammatory
state
triggered
continuous
antigenic
stimulation,
may
ultimately
increase
all-cause
mortality.
general,
less
capable
respond
neo-antigens,
because
lower
naïve
T
cells
frequency.
they
have
expansion
memory
shrinkage
cell
diversity
repertoire.
When
infected
SARS-CoV-2,
young
people
present
milder
as
frequently
clear
virus
through
efficient
response.
Indeed,
antibody-secreting
follicular
helper
thought
be
effectively
activated
patients
favorable
prognosis.
contrast,
more
prone
uncontrolled
activation
leads
cytokine
release
syndrome
tissue
damage.
failure
trigger
effective
combination
higher
pro-inflammatory
tonus
explain
why
do
not
appropriately
control
viral
replication
potential
clinical
consequences
storm,
endothelial
injury
disseminated
organ
injury.
Enhancing
efficacy
important
issue
for
infection
resolution
well
appropriate
generation
upon
vaccination,
while
inhibiting
inflammaging
likely
emerge
complementary
therapeutic
approach
management
severe
Cells,
Год журнала:
2022,
Номер
11(3), С. 359 - 359
Опубликована: Янв. 21, 2022
Acute
inflammation
is
a
physiological
response
to
injury
or
infection,
with
cascade
of
steps
that
ultimately
lead
the
recruitment
immune
cells
clear
invading
pathogens
and
heal
wounds.
However,
chronic
arising
from
continued
presence
initial
trigger,
dysfunction
signalling
and/or
effector
pathways,
harmful
health.
While
successful
ageing
in
older
adults,
including
centenarians,
associated
low
levels
inflammation,
elevated
increases
risk
poor
health
death.
Hence
has
been
described
as
one
seven
pillars
ageing.
Age-associated
sterile,
chronic,
low-grade
commonly
termed
inflammageing-it
not
simply
consequence
increasing
chronological
age,
but
also
marker
biological
ageing,
multimorbidity,
mortality
risk.
inflammageing
was
initially
thought
be
caused
by
"continuous
antigenic
load
stress",
reports
last
two
decades
describe
much
more
complex
phenomenon
involving
cellular
senescence
system.
In
this
review,
we
explore
some
main
sources
consequences
context
immunosenescence
highlight
potential
interventions.
particular,
assess
contribution
age-associated
identify
patterns
pro-
anti-inflammatory
markers
characteristic
inflammageing,
alterations
system
finally
ways
diet,
exercise,
pharmacological
interventions
can
reduce
thus,
improve
later
life
Journal of sport and health science/Journal of Sport and Health Science,
Год журнала:
2022,
Номер
12(1), С. 8 - 35
Опубликована: Окт. 29, 2022
Exercise
has
long
been
known
for
its
active
role
in
improving
physical
fitness
and
sustaining
health.
Regular
moderate-intensity
exercise
improves
all
aspects
of
human
health
is
widely
accepted
as
a
preventative
therapeutic
strategy
various
diseases.
It
well-documented
that
maintains
restores
homeostasis
at
the
organismal,
tissue,
cellular,
molecular
levels
to
stimulate
positive
physiological
adaptations
consequently
protect
against
pathological
conditions.
Here
we
mainly
summarize
how
affects
major
hallmarks
health,
including
integrity
barriers,
containment
local
perturbations,
recycling
turnover,
integration
circuitries,
rhythmic
oscillations,
homeostatic
resilience,
hormetic
regulation,
well
repair
regeneration.
Furthermore,
current
understanding
mechanisms
responsible
beneficial
response
exercise.
This
review
aimed
providing
comprehensive
summary
vital
biological
through
which
opens
window
application
other
interventions.
We
hope
continuing
investigation
this
field
will
further
increase
our
processes
involved
thus
get
us
closer
identification
new
therapeutics
improve
quality
life.
GeroScience,
Год журнала:
2023,
Номер
45(6), С. 3211 - 3239
Опубликована: Июль 26, 2023
Abstract
Physical
activity,
including
walking,
has
numerous
health
benefits
in
older
adults,
supported
by
a
plethora
of
observational
and
interventional
studies.
Walking
decreases
the
risk
or
severity
various
outcomes
such
as
cardiovascular
cerebrovascular
diseases,
type
2
diabetes
mellitus,
cognitive
impairment
dementia,
while
also
improving
mental
well-being,
sleep,
longevity.
Dose-response
relationships
for
walking
duration
intensity
are
established
adverse
outcomes.
Walking’s
favorable
effects
on
factors
attributed
to
its
impact
circulatory,
cardiopulmonary,
immune
function.
Meeting
current
physical
activity
guidelines
briskly
30
min
per
day
5
days
can
reduce
several
age-associated
diseases.
Additionally,
low-intensity
exercise,
exerts
anti-aging
helps
prevent
age-related
making
it
powerful
tool
promoting
healthy
aging.
This
is
exemplified
lifestyles
individuals
Blue
Zones,
regions
world
with
highest
concentration
centenarians.
other
activities
contribute
significantly
longevity
these
regions,
being
an
integral
part
their
daily
lives.
Thus,
incorporating
into
routines
encouraging
walking-based
interventions
be
effective
strategy
aging
all
populations.
The
goal
this
review
provide
overview
vast
consistent
evidence
supporting
specific
focus
discuss
outcomes,
prevention
Furthermore,
will
delve
molecular
cellular
mechanisms
aging,
providing
insights
underlying
biological
through
which
beneficial
effects.