A Global Overview of Dietary Supplements: Regulation, Market Trends, Usage during the COVID-19 Pandemic, and Health Effects

Nutrients, Год журнала: 2023, Номер 15(15), С. 3320 - 3320

Опубликована: Июль 26, 2023

Over the last 20 years, use of dietary supplements (DS) has continued to grow in many countries. Due public health crisis brought on by COVID-19 pandemic and amidst fears regarding vaccines their low supply regions world, there been a marked interest DS as alternative means protecting against treating this emerging disease, well boosting immune system minimizing risk inflammation. Despite lack evidence suggest efficacy, surge sales reported parts world. Questions have also raised about effects associated with due increased during crisis. Numerous scientific studies demonstrated beneficial properties some adverse even toxic effects. In addition, given current global issue, review is needed establish status before The aim summarize impact incidence pandemic, regulation market trends. First, we provide an overview DS, including comprehensive legislative regulatory aspects USA, China, EU, Algeria. Second, describe prevalence most commonly consumed efficacy prophylactic modality era COVID-19. Additionally, examine structure size countries that predominantly produce import them, its trend, growth. Finally, review, discuss profile users.

Язык: Английский

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The Influence of Nutritional Factors on Immunological Outcomes

Frontiers in Immunology, Год журнала: 2021, Номер 12

Опубликована: Май 31, 2021

Through food intake, humans obtain a variety of nutrients that are essential for growth, cellular function, tissue development, energy, and immune defense. A special interaction between gut-associated lymphoid occurs in the intestinal tract. Enterocytes barrier act as sensors antigens from microbiota, which they deliver to underlying system lamina propria, triggering an response. Studies investigating mechanism influence nutrition on immunological outcomes have highlighted important role macronutrients (proteins, carbohydrates, fatty acids) micronutrients (vitamins, minerals, phytochemicals, antioxidants, probiotics) modulating homeostasis. Nutrients exert their innate immunity inflammation by regulating expression TLRs, pro- anti-inflammatory cytokines, thus interfering with cell crosstalk signaling. Chemical substrates derived nutrient metabolism may cofactors or blockers enzymatic activity, influencing molecular pathways chemical reactions associated microbial killing, inflammation, oxidative stress. Immune function appears be influenced certain form parts membrane structure involved energy production prevention cytotoxicity. also contribute initiation regulation adaptive responses B T lymphocyte differentiation, proliferation activation, antibody production. The purpose this review is present available data field nutritional immunology elucidate complex dynamic relationship system, delineation will lead optimized regimens disease patient care.

Язык: Английский

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The Impact of Nutrition on the COVID-19 Pandemic and the Impact of the COVID-19 Pandemic on Nutrition

Nutrients, Год журнала: 2021, Номер 13(6), С. 1752 - 1752

Опубликована: Май 21, 2021

The coronavirus disease 2019 (COVID-19) pandemic has had significant morbidity, mortality, social and financial implications for the global population. Despite this knowledge, we still know very little about how COVID-19 infection affects quality of life resulting from changes in nutritional behaviour and, conversely, nutrition could modulate epidemiology COVID-19. In addition, isolation most have experienced due to regulations imposed by governments during may also effects on our behaviour. It is possible that interventions incidence mortality rates. purpose review evaluate current status research topic as it relates pandemic.

Язык: Английский

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The role of vitamin B12 in viral infections: a comprehensive review of its relationship with the muscle–gut–brain axis and implications for SARS-CoV-2 infection

Nutrition Reviews, Год журнала: 2021, Номер 80(3), С. 561 - 578

Опубликована: Окт. 15, 2021

This comprehensive review establishes the role of vitamin B12 as adjunct therapy for viral infections in treatment and persistent symptoms COVID-19, focusing on related to muscle-gut-brain axis. Vitamin can help balance immune responses better fight infections. Furthermore, data from randomized clinical trials meta-analysis indicate that forms methylcobalamin cyanocobalamin may increase serum levels, resulted decreased methylmalonic acid homocysteine concentrations, pain intensity, memory loss, impaired concentration. Among studies, there is much variation doses, chemical forms, supplementation time, administration routes. Larger analysis markers such total B12, holotranscobalamin, acid, folic and, if possible, polymorphisms methylation genes need be conducted with people without COVID-19 or who have had facilitate proper form administered individual treatment.

Язык: Английский

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Demographic and social determinants of cognitive dysfunction following hospitalization for COVID-19

Journal of the Neurological Sciences, Год журнала: 2022, Номер 438, С. 120146 - 120146

Опубликована: Янв. 7, 2022

Язык: Английский

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Surge of mucormycosis during the COVID-19 pandemic

Travel Medicine and Infectious Disease, Год журнала: 2023, Номер 52, С. 102557 - 102557

Опубликована: Фев. 20, 2023

Patients with respiratory viral infections are more likely to develop co-infections leading increased fatality. Mucormycosis is an epidemic amidst the COVID-19 pandemic that conveys a 'double threat' global health fraternity. caused by Mucorales group of fungi and exhibits acute angioinvasion generally in immunocompromised patients. The most familiar foci sinuses (39%), lungs (24%), skin tissues (19%) where overall dissemination occurs 23% cases. mortality rate case disseminated mucormycosis found be 96%. Symptoms mostly nonspecific often resemble other common bacterial or fungal infections. Currently, COVID-19-associated (CAM) being reported from number countries such as USA, Turkey, France, Mexico, Iran, Austria, UK, Brazil, Italy, while India hotspot for this deadly co-infection, accounting approximately 28,252 cases up June 8, 2021. It strikes patients within 12-18 days after recovery, nearly 80% require surgery. Nevertheless, can reach 94% if diagnosis delayed remains untreated. Sometimes sole predisposing factor CAM. Therefore, study may provide comprehensive resource clinicians researchers dealing infections, intending link potential translational knowledge prospective therapeutic challenges counter opportunistic pathogen.

Язык: Английский

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Exploring the Interplay of Food Security, Safety, and Psychological Wellness in the COVID-19 Era: Managing Strategies for Resilience and Adaptation

Foods, Год журнала: 2024, Номер 13(11), С. 1610 - 1610

Опубликована: Май 22, 2024

The global population surge presents a dual challenge and opportunity in the realms of food consumption, safety, mental well-being. This necessitates projected 70% increase production to meet growing demands. Amid this backdrop, ongoing COVID-19 pandemic exacerbates these issues, underscoring need for deeper understanding intricate interplay between consumption patterns health dynamics during crisis. Mitigating spread hinges upon rigorous adherence personal hygiene practices heightened disease awareness. Furthermore, maintaining stringent quality safety standards across both public private sectors is imperative safeguarding containing viral transmission. Drawing existing research, study delves into pandemic’s impact on health, habits, protocols. Through comprehensive analysis, it aims elucidate nuanced relationship among food, well-being amid pandemic, highlighting synergistic effects that underpin holistic human welfare. Our offers novel approach by integrating psychological wellness with security safety. In conceiving review, we aimed comprehensively explore security, backdrop pandemic. review structured encompass thorough examination synthesizing insights multifaceted relationships patterns, dynamics, protocols findings provide valuable practical recommendations enhancing well-being, thus supporting academic research real-world applications crisis management policy development.

Язык: Английский

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Higher Serum Monolaurin Is Associated with a Lower Risk of COVID-19: Results from a Prospective Observational Cohort Study

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(6), С. 2452 - 2452

Опубликована: Март 10, 2025

The COVID-19 pandemic has stimulated the search for effective preventive and therapeutic agents. In recent years, many studies have considered effects of different nutrients. This study aimed to investigate association between serum monolaurin levels risk developing among healthcare workers. this prospective observational cohort study, 2712 workers from University Hospital “Maggiore della Carità” in Novara, Italy were enrolled. Participants underwent blood sampling followed up six months evaluate protective role against infection. Monolaurin quantified using targeted metabolomic analysis. consisted 1000 individuals with a mean age 46.4 predominantly female. Higher concentrations significantly associated lower SARS-CoV-2 infection at both 3- 6-month follow-ups. optimal cut-off value monolaurin, which provides efficacy, was identified as 0.45 µg/mL. appear be reduced COVID-19, suggesting its potential dietary supplement contributes growing body evidence supporting factors management prevention infectious diseases highlights metabolomics identifying prophylactic biomarkers.

Язык: Английский

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Knowledge, Attitudes, and Practices Related to Dietary Supplementation, before and during the COVID-19 Pandemic: Findings from a Cross-Sectional Survey in the Lebanese Population

International Journal of Environmental Research and Public Health, Год журнала: 2021, Номер 18(16), С. 8856 - 8856

Опубликована: Авг. 23, 2021

At the start of 2020, a new coronavirus (COVID-19) invaded world leading to death 3.92 million people. Sadly, date, no remedy has been discovered for this virus. Preventive vaccines have under investigation, but were unavailable until December 2020. Clinical deficiencies nutrients may increase susceptibility infections. This knowledge provided an incentive some dietary supplement (DS) manufacturers advertise their products as COVID-19 preventatives or cures without any substantiation, targeting mainly social media fans. The objective research was assess usage, and attitudes towards supplementation before during pandemic among Lebanese A cross-sectional study conducted based on convenience sample (N = 2966) information from participants aged 18 years above collected about periods pandemic. Our findings showed that DSs changed when emerged people believed can improve health strengthen immunity. Despite rise in DS prescription by healthcare professionals, prevalence use decreased 73.3% 69.9% (p < 0.001). Study results declared weekly daily estimated intake had increased compared pandemic, 14% 15.6% antioxidants 0.014), 35.3% 42.1% vitamin C 0.001), 35.5% 41% D 15.2% 17.5% E 0.002), 18.8% 29.3% zinc 0.001) other vitamins minerals (from 9% 10.9%, p Binary logistic regression indicated 4 times higher those infected with COVID-19, 30 who used take 1.5 worked medical sector. To conclude, there is crucial need awareness regarding DSs.

Язык: Английский

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Diets and dietary supplements used during the COVID-19 pandemic in the United Arab Emirates: A cross-sectional survey

Saudi Pharmaceutical Journal, Год журнала: 2022, Номер 30(4), С. 421 - 432

Опубликована: Янв. 29, 2022

Since the beginning of Coronavirus disease 2019 (COVID-19) pandemic, there has been a marked increase in use diets and dietary supplements (DDS) for prevention treatment this emerging disease. While DDS are generally regarded as harmless, little evidence exists on safety efficacy their COVID-19.To investigate pattern determinants among United Arab Emirates (UAE) population COVID-19.Cross-sectional web-based survey.Adults residing UAE.Participants (n = 2,060) UAE were recruited from databases Supreme Council Family Affairs - Sharjah networks various Emirates.Prevalence different COVID-19 UAE, sources information use.The majority participants reported using form understudy, with special foods being most common (95.5%), followed by intake citrus fruits (62.1%), (56.6%), increased water (50%), herbal teas (38.4%). Only 20% main source to be health care practitioners, relying either social media (40.4%) or family friends (28.7%). After adjustment, female gender, older age (>40 years), Asian ethnicities characteristics associated higher odds modalities also correlates reporting practitioners findings showed widespread COVID-19. The study was mainly guided marginal role practitioners. These call more integrative approach towards ensure its proper safe use.

Язык: Английский

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