Journal of Infection and Public Health,
Journal Year:
2023,
Volume and Issue:
16(8), P. 1276 - 1280
Published: June 5, 2023
COVID-19
pandemic
adversely
affected
healthcare
workers
(HCWs).
Here,
we
evaluate
the
occurence
of
long-COVID-19
symtoms
among
HCWs.
This
is
a
questionnaire-based
study
HCWs
who
had
in
two
medical
centers
Saudi
Arabia
and
were
mostly
vaccinated.
The
included
243
with
mean
age
(+
SD)
36.1
7.6)
years.
Of
them,
223
(91.8%)
three
doses
vaccine,
12
(4.9%)
four
doses,
5
(2.1%)
doses.
most
common
symptoms
at
start
illness
cough
(180,
74.1%),
shortness
breath
(124,
51%),
muscle
ache
(117,
48.1%),
headache
(113,
46.5%),
sore
throat
(111,
45.7%),
diarrhea
(109,
44.9%)
loss
taste
(108,
44.4%).
Symptoms
lasted
for<
one
week
117
(48.1%),>
and<
1
month
89
(36.6%),>
2
months
3
9
(3.7%),
and>
15
(6.2%).
main
present>
hair
(8,
3.3%),
(5,
2.1%),
2.1%).
A
binomial
regression
analysis
showed
no
relationship
between
persistence
for>
other
demographic
or
clinical
characteristics.
low
rate
long-COVID>
during
Omicron-wave
vaccinated
significant
comorbidities.
Furhter
studies
are
needed
to
examine
effect
different
vaccines
on
Science Translational Medicine,
Journal Year:
2024,
Volume and Issue:
16(773)
Published: Nov. 13, 2024
Long
Covid
is
defined
by
a
wide
range
of
symptoms
that
persist
after
the
acute
phase
severe
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
infection.
Commonly
reported
include
fatigue,
weakness,
postexertional
malaise,
and
cognitive
dysfunction,
with
many
other
reported.
Symptom
range,
duration,
severity
are
highly
variable
partially
overlap
myalgic
encephalomyelitis/chronic
fatigue
post-acute
infectious
syndromes,
highlighting
opportunities
to
define
shared
mechanisms
pathogenesis.
Potential
diverse,
including
persistence
viral
reservoirs,
dysregulated
immune
responses,
direct
damage
tissues
targeted
SARS-CoV-2,
inflammation
driven
reactivation
latent
infections,
vascular
endothelium
activation
or
subsequent
thromboinflammation,
autoimmunity,
metabolic
derangements,
microglial
activation,
microbiota
dysbiosis.
The
heterogeneity
baseline
characteristics
people
Covid,
as
well
varying
states
immunity
therapies
given
at
time
infection,
have
made
etiologies
difficult
determine.
Here,
we
examine
progress
on
preclinical
models
for
review
being
in
clinical
trials,
need
large
human
studies
further
development
better
understand
Covid.
Such
will
inform
trials
treatments
benefit
those
living
this
condition.
Nervenheilkunde,
Journal Year:
2025,
Volume and Issue:
44(01/02), P. 16 - 23
Published: Feb. 1, 2025
Zusammenfassung
Nach
aktuellen
Schätzungen
leiden
ca.
5–10
%
aller
symptomatisch
Infizierten
nach
Abklingen
der
akuten
COVID-19-Erkrankung
unter
länger
anhaltenden
gesundheitlichen
Beeinträchtigungen.
Psychische
Symptome
und
kognitive
Beeinträchtigungen
zählen
zu
häufigen
Symptomen
von
Long-
insbesondere
Post-COVID.
Während
sich
für
Erwachsene
zahlreiche
Publikationen
Post-COVID
finden,
ist
die
Datenlage
Kinder
Adoleszente
verhältnismäßig
dünn
uneinheitlich.
Angesichts
weniger
dramatischer
Akutverläufe
in
dieser
Gruppe
Assoziation
Schwere
des
Akutverlaufs
zur
Wahrscheinlichkeit
Auftretens
war
nicht
mit
einem
bedeutsamen
Auftreten
gerechnet
worden.
Insbesondere
hinsichtlich
ihrer
psychischen
kognitiven
Entwicklungen
sind
aber
besonders
durch
störende
Einflüsse
gefährdet.
Diese
Gefährdungen
können
Coronavirus-Erkrankung
direkt
ausgehen.
Auch
Maßnahmen
Eindämmung
Pandemie
haben
wesentlich
Entwicklung
Kindern
Adoleszenten
eingegriffen.
Für
das
Verständnis
bei
Therapieansätzen
Kenntnis
vorliegenden
Forschungsergebnisse
relevant.
Dieser
Artikel
fasst
daher
aktuelle
Wissen
um
Long-COVID
psychischer
kognitiver
zusammen.
Human Vaccines & Immunotherapeutics,
Journal Year:
2025,
Volume and Issue:
21(1)
Published: March 13, 2025
This
systematic
literature
review
summarizes
the
evidence
across
56
publications
and
pre-prints
(January
2020–July
2023)
with
low-risk
of
bias
based
on
JBI
critical
appraisal,
that
report
adjusted
estimates
for
relationship
between
COVID-19
vaccination
Post-COVID-19
Condition
(PCC)
by
timing
relative
to
infection
or
PCC-onset.
Comparisons
vaccine
effectiveness
(aVE)
against
≥1
PCC
(vs.
unvaccinated)
study
characteristics
known
impact
burden
VE
other
endpoints
were
possible
31
studies
where
preceded
infection.
Seventy-seven
percent
pre-infection
aVE
statistically
significant
(range:
7%–95%).
Statistically
slightly
higher
mRNA
14%–84%)
than
non-mRNA
vaccines
16%–38%)
ranges
before
during
Omicron
overlapped.
Our
findings
suggest
SARS-CoV-2
reduces
risk
regardless
type,
number
doses
received,
definition,
predominant
variant,
severity
acute
infections
included.
npj Digital Medicine,
Journal Year:
2025,
Volume and Issue:
8(1)
Published: March 19, 2025
Abstract
Understanding
the
factors
associated
with
persistent
symptoms
after
SARS-CoV-2
infection
is
critical
to
improving
long-term
health
outcomes.
Using
a
wearable-derived
behavioral
and
physiological
dataset
(
n
=
20,815),
we
identified
individuals
characterized
by
self-reported
fatigue
shortness
of
breath
infection.
Compared
symptom-free
COVID-19
positive
(n
150)
negative
controls
150),
these
50)
had
higher
resting
heart
rates
(mean
difference
2.37/1.49
bpm)
lower
daily
step
counts
3030/2909
steps
fewer),
even
at
least
three
weeks
prior
In
addition,
were
significant
reduction
in
mean
quality
life
(WHO-5,
EQ-5D),
before
Here
show
that
may
be
pre-existing
fitness
levels
or
conditions.
These
findings
additionally
highlight
potential
wearable
devices
track
dynamics
provide
valuable
insights
into
outcomes
infectious
diseases.
BMC Infectious Diseases,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: April 2, 2025
Health
services
planning
and
mechanism-focused
research
would
benefit
from
a
clearer
picture
of
symptoms,
impact,
personal
priorities
in
post-COVID-19
syndrome
(PCS).
This
study
aimed
to
provide
estimates
the
symptom,
function,
quality
life
(QOL)
impact
PCS.
People
living
Quebec,
aged
≥
18,
were
eligible
for
Québec
Action
for/pour
le
Post-COVID
(QAPC)
if
they
had
symptoms
lasting
more
than
4
weeks
post-acute
SARS-CoV-2
infection,
with
or
without
positive
COVID-19
test.
Recruitment
was
through
conventional
social
media
between
September
2022
December,
31,
2023.
Standardized
individualized
questionnaires,
French
English,
accessed
an
online
portal.
We
report
cross-sectional
results
baseline
visit.
Individuals
(n=535)
spontaneously
reported
attributable
average
4.5
organ
systems.
Fatigue
most
frequent.
Effects
on
function
moderate
severe
already
persisted
year
majority.
Personal
intervention
included
fatigue
post-exercise
malaise
(PEM),
cognitive
shortness
breath,
impaired
taste
smell.
Except
PEM,
women
men
did
not
differ
importantly
measures
PCS
while
older
age
associated
lower
impact.
Symptom
clusters
defined
range
severity,
pervasive
symptom
at
all
levels
severity.
Participants
this
are
likely
be
representative
those
seeking
health
care
Canada
can
inform
next
steps
clinical,
research,
planning.
Diagnostics,
Journal Year:
2024,
Volume and Issue:
14(11), P. 1168 - 1168
Published: May 31, 2024
Long
COVID,
characterized
by
a
persistent
symptom
spectrum
following
SARS-CoV-2
infection,
poses
significant
health,
social,
and
economic
challenges.
This
review
aims
to
consolidate
knowledge
on
its
epidemiology,
clinical
features,
underlying
mechanisms
guide
global
responses;
