Photothermal Nanomaterials: A Powerful Light-to-Heat Converter

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(11), P. 6891 - 6952

Published: May 3, 2023

All forms of energy follow the law conservation energy, by which they can be neither created nor destroyed. Light-to-heat conversion as a traditional yet constantly evolving means converting light into thermal has been enduring appeal to researchers and public. With continuous development advanced nanotechnologies, variety photothermal nanomaterials have endowed with excellent harvesting capabilities for exploring fascinating prospective applications. Herein we review latest progresses on nanomaterials, focus their underlying mechanisms powerful light-to-heat converters. We present an extensive catalogue nanostructured materials, including metallic/semiconductor structures, carbon organic polymers, two-dimensional materials. The proper material selection rational structural design improving performance are then discussed. also provide representative overview techniques probing photothermally generated heat at nanoscale. finally recent significant developments applications give brief outlook current challenges future directions nanomaterials.

Language: Английский

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Advances in nanomaterials for photodynamic therapy applications: Status and challenges

Biomaterials, Journal Year: 2020, Volume and Issue: 237, P. 119827 - 119827

Published: Jan. 27, 2020

Language: Английский

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MXene/Polymer Membranes: Synthesis, Properties, and Emerging Applications

Chemistry of Materials, Journal Year: 2020, Volume and Issue: 32(5), P. 1703 - 1747

Published: Feb. 10, 2020

2D transition metal carbides or nitrides, known as MXenes, are a new family of materials with close to 30 members experimentally synthesized and dozens more theoretically investigated. Because the abundant surface terminations, MXenes have been compounded various by multi-interactions. In addition prevented aggregation oxidation MXene flakes, MXene/polymer membranes exhibit outstanding mechanical, thermal, electrical properties due synergistic effects. However, relatively little is currently about special review on progress synthesis, properties, applications has not reported date. Herein, this Review starts an introduction synthesis MXenes. Then development will be discussed, which aims summarize approaches fabricating their fascinating properties. The focus then turns exciting potential in fields such filtration, electromagnetic interference (EMI) shielding, energy storage devices, wearable electronics, etc. Finally, outlooks perspectives for future challenges prospects provided.

Language: Английский

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Photodynamic and Photothermal Therapies: Synergy Opportunities for Nanomedicine

ACS Nano, Journal Year: 2023, Volume and Issue: 17(9), P. 7979 - 8003

Published: April 27, 2023

Tumoricidal photodynamic (PDT) and photothermal (PTT) therapies harness light to eliminate cancer cells with spatiotemporal precision by either generating reactive oxygen species or increasing temperature. Great strides have been made in understanding biological effects of PDT PTT at the cellular, vascular tumor microenvironmental levels, as well translating both modalities clinic. Emerging evidence suggests that may synergize due their different mechanisms action, nonoverlapping toxicity profiles make such combination potentially efficacious. Moreover, PDT/PTT combinations gained momentum recent years development multimodal nanoplatforms simultaneously incorporate photodynamically- photothermally active agents. In this review, we discuss how combining can address limitations each modality alone enhance treatment safety efficacy. We provide an overview literature featuring dual nanoparticles analyze strengths various nanoparticle design strategies. also detail sequence dose affect cellular states, pathophysiology drug delivery, ultimately shaping response. Lastly, common experimental pitfalls complicate preclinical assessment propose rational guidelines elucidate underlying interactions.

Language: Английский

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2D Layered Materials: Synthesis, Nonlinear Optical Properties, and Device Applications

Laser & Photonics Review, Journal Year: 2019, Volume and Issue: 13(12)

Published: Nov. 20, 2019

Abstract In recent years, 2D layered materials, including graphene, topological insulators, transition metal dichalcogenides, black phosphorus, MXenes, graphitic carbon nitride, and metal‐organic frameworks, have attracted considerable interest due to their potential applications in the fields of physics, chemistry, biology, energy. Their rise field nonlinear photonics began around 2009 has become an important research direction. Here, synthesis techniques, optical properties, integration strategies, device materials are reviewed. terms focus is on saturable absorption Kerr nonlinearity. On this basis, various pulsed lasers, fiber solid‐state waveguide related phenomenon, summarized. addition, novel devices using such as modulators, polarizers, switchers, even all‐optical device, also involved. It believed that development will continue deepen, thus laying a good foundation for its practical application.

Language: Английский

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Multifunctional Photoactive Hydrogels for Wound Healing Acceleration

ACS Nano, Journal Year: 2021, Volume and Issue: 15(12), P. 18895 - 18930

Published: Dec. 6, 2021

Light is an attractive tool that has a profound impact on modern medicine. Particularly, light-based photothermal therapy (PTT) and photodynamic (PDT) show great application prospects in the prevention of wound infection promoting healing. In addition, hydrogels have shown advantages field dressings due to their excellent biochemical effects. Therefore, multifunctional photoresponsive (MPRHs) integrate light are increasingly used biomedicine, especially repair. However, comprehensive review MPRHs for regeneration still lacking. This first focuses various types prepared by diverse photosensitizers, agents (PHTAs) including transition metal sulfide/oxides nanomaterials, nanostructure-based PHTAs, carbon-based conjugated polymer or complex-based and/or (PHDAs) such as ZnO-based, black-phosphorus-based, TiO2-based, small organic molecule-based PHDAs. We also then discuss how PTT, PDT, photothermal/photodynamic synergistic can modulate microenvironments bacteria inhibit infection. Overall, with both therapeutic tissue capabilities been discussed existing challenges, well future research directions management argued.

Language: Английский

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Mito‐Bomb: Targeting Mitochondria for Cancer Therapy

Advanced Materials, Journal Year: 2021, Volume and Issue: 33(43)

Published: Sept. 12, 2021

Abstract Cancer has been one of the most common life‐threatening diseases for a long time. Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) have limited effects due to drug resistance, unsatisfactory treatment efficiency, side effects. In recent years, photodynamic therapy (PDT), photothermal (PTT), chemodynamic (CDT) utilized owing their high selectivity, minor minimal toxicity. Accumulating evidence demonstrated that selective delivery drugs specific subcellular organelles can significantly enhance efficiency therapy. Mitochondria‐targeting therapeutic strategies are promising therapy, which is attributed essential role mitochondria in regulation cell apoptosis, metabolism, more vulnerable hyperthermia oxidative damage. Herein, rational design, functionalization, applications diverse mitochondria‐targeting units, involving organic phosphine/sulfur salts, quaternary ammonium (QA) peptides, transition‐metal complexes, guanidinium or bisguanidinium, well including PDT, PTT, CDT, others summarized. This review aims furnish researchers with deep insights hints design novel agents

Language: Английский

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Recent Advances in Functional 2D MXene‐Based Nanostructures for Next‐Generation Devices

Advanced Functional Materials, Journal Year: 2020, Volume and Issue: 30(49)

Published: Sept. 9, 2020

Abstract Similar to graphene and black phosphorus (BP), 2D transition metal carbides nitrides (MXenes) are of great interest in a variety fields, such as energy storage conversion, sensors, electromagnetic interference (EMI) shielding, photothermal therapy due their excellent conductivity hydrophilicity, large specific capacitance, high effect, superior electrochemical performance. To further broaden applicable ranges beyond existing boundaries fully exploit these potentials, functional MXene nanostructures recent years have been rationally designed developed by various approaches, doping strategies, surface functionalization, hybridization, for next‐generation devices with the merits low power consumption, intelligence, high‐integration chips. This review provides an overview synthetic routes fundamental properties nanostructures, including surface‐modified MXenes mixed‐dimensional MXene‐based heterostructures, highlights state‐of‐the‐art progress applications regard catalysis, photodetectors, EMI degradation, biomedical applications, presents challenges perspectives burgeoning fields. It is hoped that this will inspire more efforts toward research on new satisfy growing requirements systems.

Language: Английский

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Two-dimensional nanomaterials: fascinating materials in biomedical field

Science Bulletin, Journal Year: 2019, Volume and Issue: 64(22), P. 1707 - 1727

Published: Sept. 20, 2019

Language: Английский

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Development of Point-of-Care Biosensors for COVID-19

Frontiers in Chemistry, Journal Year: 2020, Volume and Issue: 8

Published: May 27, 2020

Coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic. The deleterious effects of coronavirus have prompted the development diagnostic tools to manage its spread. While conventional technologies such as quantitative real time polymerase chain reaction (qPCR) been broadly used detect COVID-19, they are time-consuming, labor-intensive and unavailable in remote settings. Point-of-care (POC) biosensors, including chip-based paper-based biosensors typically low-cost user-friendly, which offer tremendous potential for rapid medical diagnosis. This mini review article discusses recent advances POC COVID-19. First, made polydimethylsiloxane (PDMS), papers other flexible materials textile, film carbon nanosheets reviewed. advantages each along with commercially available COVID-19 highlighted. Lastly, existing challenges future perspectives developing robust rapidly identify spread briefly discussed.

Language: Английский

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