Photothermal antibacterial materials to promote wound healing

Journal of Controlled Release, Journal Year: 2023, Volume and Issue: 363, P. 180 - 200

Published: Sept. 27, 2023

Language: Английский

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Injectable chitosan hydrogels tailored with antibacterial and antioxidant dual functions for regenerative wound healing

Carbohydrate Polymers, Journal Year: 2022, Volume and Issue: 298, P. 120103 - 120103

Published: Sept. 15, 2022

Language: Английский

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A nanofibrous membrane loaded with doxycycline and printed with conductive hydrogel strips promotes diabetic wound healing in vivo

Acta Biomaterialia, Journal Year: 2022, Volume and Issue: 152, P. 60 - 73

Published: Aug. 30, 2022

Language: Английский

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A Versatile Glycopeptide Hydrogel Promotes Chronic Refractory Wound Healing Through Bacterial Elimination, Sustained Oxygenation, Immunoregulation, and Neovascularization

Advanced Functional Materials, Journal Year: 2023, Volume and Issue: 33(49)

Published: July 26, 2023

Abstract Chronic refractory wounds have become a severe threat to public health and are characterized by repeated bacterial infections, persistent hypoxia, abnormal immune regulation, obstruction of angiogenesis. However, current treatment strategies usually perform only one or two therapeutic functions cannot satisfy the dynamic complex demands chronic wound healing. Herein, versatile Schiff base borate ester cross‐linked glycopeptide hydrogel is prepared from phenylboronic acid‐grafted ε‐polylysine (EPBA), epigallocatechin‐3‐gallate (EGCG), oxidized alginate. Customized polydopamine‐coated honeycomb MnO 2 nanoparticles loaded with herb‐derived salvianolic acid B (PHMS) embedded into before gelation. Under distinct acidic oxidative microenvironment wounds, gradually dissociates, released EPBA effectively eliminates bacteria, while EGCG PHMS eradicates reactive oxygen nitrogen species, promotes M2 polarization macrophages, continuously generates oxygen. Then further disintegrates, angiogenesis through PI3K/Akt pathway. The accelerates Staphylococcus aureus ‐infected diabetic cutaneous repair in vivo promising candidate dressing for

Language: Английский

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Facile fabrication of self-healing, injectable and antimicrobial cationic guar gum hydrogel dressings driven by hydrogen bonds

Carbohydrate Polymers, Journal Year: 2023, Volume and Issue: 310, P. 120723 - 120723

Published: Feb. 20, 2023

Language: Английский

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Chitosan-based self-healing hydrogel dressing for wound healing

Advances in Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 332, P. 103267 - 103267

Published: Aug. 3, 2024

Language: Английский

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Multifunctional cinnamaldehyde-tannic acid nano-emulsion/chitosan composite film for mushroom preservation

Food Hydrocolloids, Journal Year: 2023, Volume and Issue: 145, P. 109111 - 109111

Published: July 26, 2023

Language: Английский

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Chitosan Hydrogel as Tissue Engineering Scaffolds for Vascular Regeneration Applications

Gels, Journal Year: 2023, Volume and Issue: 9(5), P. 373 - 373

Published: May 1, 2023

Chitosan hydrogels have a wide range of applications in tissue engineering scaffolds, mainly due to the advantages their chemical and physical properties. This review focuses on application chitosan scaffolds for vascular regeneration. We introduced these following aspects: progress regeneration modification improve Finally, this paper discusses prospects

Language: Английский

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Natural Products from Herbal Medicine Self‐Assemble into Advanced Bioactive Materials

Advanced Science, Journal Year: 2024, Volume and Issue: unknown

Published: July 21, 2024

Novel biomaterials are becoming more crucial in treating human diseases. However, many materials require complex artificial modifications and synthesis, leading to potential difficulties preparation, side effects, clinical translation. Recently, significant progress has been achieved terms of direct self-assembly natural products from herbal medicine (NPHM), an important source for novel medications, resulting a wide range bioactive supramolecular including gels, nanoparticles. The NPHM-based produced renewable resources, simple prepare, have demonstrated multi-functionality slow-release, smart-responsive release, especially possess powerful biological effects treat various In this review, revealed as emerging, revolutionary, promising strategy. development, advantages, limitations NPHM, well the advantageous position materials, first reviewed. Subsequently, systematic comprehensive analysis strategies specific seven major classes NPHM is highlighted. Insights into influence structural features on formation also provided. Finally, drivers preparations summarized, emphasizing biomedical applications, future scientific challenges, opportunities, with hope igniting inspiration research applications.

Language: Английский

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Design of Fatigue‐Resistant Hydrogels

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 34(21)

Published: Jan. 4, 2024

Abstract Hydrogels are made tough to resist crack propagation. However, for seamless integration into devices and machines, it necessitates robustness against cyclic loads. Central this objective is enhancing fatigue resistance, an indispensable attribute facilitating the optimal performance of hydrogels within a multitude biological contexts, spanning various plant animal tissues, as well diverse biomedical engineering areas. In review, recent research concerning behavior hydrogels, presenting comprehensive consolidation inherent mechanisms that underpin strategies aimed at fortifying summarized. A critical facet in architectural blueprint fatigue‐resistant emphasized, involving imposition spatial constraints upon main chains tips, thereby effectuating protracted delay their fracture initiation during prolonged loading. The multiscale encompassing networks, interactions, media, structures stands pivotal factor design hydrogels. It hoped review will considerably propel pragmatic deployment across array applications, thus catalyzing advancements multiple fields.

Language: Английский

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