Biomaterials, Journal Year: 2024, Volume and Issue: 311, P. 122698 - 122698
Published: July 2, 2024
Language: Английский
Gels, Journal Year: 2023, Volume and Issue: 9(7), P. 523 - 523
Published: June 27, 2023
Polymer-based hydrogels are hydrophilic polymer networks with crosslinks widely applied for drug delivery applications because of their ability to hold large amounts water and biological fluids control release based on unique physicochemical properties biocompatibility. Current trends in the development hydrogel systems involve drugs response specific triggers such as pH, temperature, or enzymes targeted reduce potential systemic toxicity. In addition, developing injectable formulations that easily used sustain during this extended time is a growing interest. Another emerging trend synthesis nano other functional substances improving loading efficacy. Following these trends, advanced possessing mechanically improved properties, controlled rates, biocompatibility focus field. More complex multi-drug combination therapies will be developed advancements. polymer-based gaining increasing attention personalized medicine tailored patient, example, combinations, target-specific delivery, improvement disease treatment effectiveness, healthcare cost reduction. Overall, application advancing rapidly, towards more efficient effective future.
Language: Английский
Citations
289
Materials Today Bio, Journal Year: 2024, Volume and Issue: 25, P. 101014 - 101014
Published: Feb. 29, 2024
Traditional hydrogel design and optimization methods usually rely on repeated experiments, which is time-consuming expensive, resulting in a slow-moving of advanced development. With the rapid development artificial intelligence (AI) technology increasing material data, AI-energized hydrogels for biomedical applications has emerged as revolutionary breakthrough materials science. This review begins by outlining history AI potential advantages using hydrogels, such prediction properties, multi-attribute optimization, high-throughput screening, automated discovery, optimizing experimental design, etc. Then, we focus various supported biomedicine, including drug delivery, bio-inks manufacturing, tissue repair, biosensors, so to provide clear comprehensive understanding researchers this field. Finally, discuss future directions prospects, new perspective research novel applications.
Language: Английский
Citations
38
Advanced Composites and Hybrid Materials, Journal Year: 2024, Volume and Issue: 7(2)
Published: March 12, 2024
Abstract Carbon materials have emerged as a rapidly advancing category of high-performance that garnered significant attention across various scientific and technological disciplines. Their exceptional biochemical properties render them highly suitable for diverse biomedical applications, including implantation, artificial joints, bioimaging, tissue bone engineering, scaffold fabrication. However, more systematic approach is required to fully exploit the potential carbon-based in realm, necessitating extensive collaborative research address existing challenges, which comprehensive long-term stability studies, surface investigate toxicity materials. This review paper aims provide overview carbon materials, elucidating their inherent advantages highlighting increasingly prominent role applications. After brief introduction carbonaceous we discuss innovative deposition strategies can be utilized artificially replicate desired properties, such biocompatibility toxicology, within complex structures. Further, this serves valuable resource harness realm Last, conclude with discussion on significance continuous exploration propelling further advancements captivating field.
Language: Английский
Citations
21
Gels, Journal Year: 2023, Volume and Issue: 9(2), P. 132 - 132
Published: Feb. 4, 2023
Hydrogels are fascinating biomaterials that can act as a support for cells, i.e., scaffold, in which they organize themselves spatially similar way to what occurs vivo. Hydrogel use is therefore essential the development of 3D systems and allows recreate cellular microenvironment physiological pathological conditions. This makes them ideal candidates biological tissue analogues application field both engineering vitro models, have ability closely mimic extracellular matrix (ECM) specific organ or tissue. Polysaccharide-based hydrogels, because their remarkable biocompatibility related polymeric constituents, interact beneficially with components. Although growing interest polysaccharide-based hydrogels biomedical evidenced by conspicuous number reviews on topic, none focused combined two important polysaccharides, chitosan pectin. Therefore, present review will discuss applications containing aforementioned natural polymers, pectin, fields modeling.
Language: Английский
Citations
36
Small, Journal Year: 2023, Volume and Issue: 20(22)
Published: Dec. 15, 2023
Hemorrhage remains a critical challenge in various medical settings, necessitating the development of advanced hemostatic materials. Hemostatic hydrogels have emerged as promising solutions to address uncontrolled bleeding due their unique properties, including biocompatibility, tunable physical characteristics, and exceptional capabilities. In this review, comprehensive overview preparation biomedical applications is provided. Particularly, with materials forms are introduced. Additionally, trauma management, surgical procedures, wound care, etc. summarized. Finally, limitations future prospects discussed evaluated. This review aims highlight hemorrhage management offer insights into clinically relevant
Language: Английский
Citations
27
ACS Materials Letters, Journal Year: 2024, Volume and Issue: 6(2), P. 627 - 639
Published: Jan. 19, 2024
Marine composites with antimicrobial fouling and fireproofing are indispensable for ocean facilities that resist extremely harsh environments. life has excited various inspirations to withstand environments, in which sandcastle worms secrete unique adhesives gluing sand shell fragments together build robust protective habitats. Herein, we design an adherable macromolecule interface containing tyramine ammonium phosphate motifs create superhighly flame-retardant excellent antibacterial functional composites. The results demonstrate the phenolic hydroxyl groups improve chemical affinity among polyphosphate, vinyl ester resin, carbon fibers due great adhesion, while also exhibiting broad-spectrum properties bacteria, mold, algae. synergistically achieve superhigh fire-safety performance beyond current levels powerfully defend human maritime confined spaces. This sandcastle-worm-inspired strategy emerges as attractive candidate super fireproof protection
Language: Английский
Citations
12
European Polymer Journal, Journal Year: 2024, Volume and Issue: 210, P. 112949 - 112949
Published: March 15, 2024
Language: Английский
Citations
10
Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 334, P. 122028 - 122028
Published: March 6, 2024
Language: Английский
Citations
9
Journal of Pharmaceutical Sciences, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
1
Smart Medicine, Journal Year: 2023, Volume and Issue: 2(3)
Published: July 5, 2023
The proper organization of cells and tissues is essential for their functionalization in living organisms. To create materials that mimic natural structures, researchers have developed techniques such as patterning, templating, printing. Although these own several advantages, processes still involve complexity, are time-consuming, high cost. better simulate with micro/nanostructures evolved millions years, the use ice templates has emerged a promising method producing biomimetic more efficiently. This article explores historical approaches taken to produce traditional structural biomaterials delves into principles underlying ice-template various applications creation materials. It also discusses most recent biomedical uses created via templates, including porous microcarriers, tissue engineering scaffolds, smart Finally, challenges potential current technology analyzed.
Language: Английский
Citations
19