Investigation of the Antibacterial Properties of Janus Micromotors Catalytic Propelled by Manganese Dioxide and Hydrogen Peroxide to Reduce Bacterial Density DOI

Yangfang Cheng,

Xiaolan Liu, Sven Rutkowski

et al.

ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 2, 2024

Between 2015 and 2017, 90% of Chinese adults were reported to have periodontitis varying degrees, highlighting the importance novel, inexpensive, affordable treatments for public. The fact that more pathogens are becoming resistant antibiotics further highlights this prevalence. This article addresses a novel micromotor capable generating reactive oxygen species, as proven by Fenton-like reaction. Such reactions allow targeting Gram-negative bacteria such

Language: Английский

Facilitating Layered Oxide Cathodes Based on Orbital Hybridization for Sodium‐Ion Batteries: Marvelous Air Stability, Controllable High Voltage, and Anion Redox Chemistry DOI

Xin‐Bei Jia,

Jingqiang Wang, Yi‐Feng Liu

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: 36(15)

Published: Nov. 1, 2023

Layered oxides have become the research focus of cathode materials for sodium-ion batteries (SIBs) due to low cost, simple synthesis process, and high specific capacity. However, poor air stability, unstable phase structure under voltage, slow anionic redox kinetics hinder their commercial application. In recent years, concept manipulating orbital hybridization has been proposed simultaneously regulate microelectronic modify surface chemistry environment intrinsically. this review, modes between atoms in 3d/4d transition metal (TM) orbitals O 2p near region Fermi energy level (E

Language: Английский

Citations

62

Metareview: a survey of active matter reviews DOI Creative Commons
Michael te Vrugt, Raphael Wittkowski

The European Physical Journal E, Journal Year: 2025, Volume and Issue: 48(2)

Published: Feb. 1, 2025

In the past years, amount of research on active matter has grown extremely rapidly, a fact that is reflected in particular by existence more than 1000 reviews this topic. Moreover, field become very diverse, ranging from theoretical studies statistical mechanics particles to applied work medical applications microrobots and biological systems artificial swimmers. This makes it difficult get an overview over as whole. Here, we provide such form metareview article surveys existing review articles books matter. Thereby, provides useful starting point for finding literature about specific

Language: Английский

Citations

2

Covalent Organic Framework‐Based Nanomotor for Multimodal Cancer Photo‐Theranostics DOI
Jie Feng,

Shi‐Peng Yang,

Yu‐Qing Shao

et al.

Advanced Healthcare Materials, Journal Year: 2023, Volume and Issue: 12(30)

Published: Aug. 9, 2023

Developing efficient integrated diagnosis and treatment agents based on fuel-free self-movement nanomotors remains challenging in antitumor therapy. In this study, a covalent organic framework (COF)-based biomimetic nanomotor composed of polypyrrole (PPy) core, porphyrin-COF shell, HCT116 cancer cell membrane coating is reported. Under near-infrared (NIR) light irradiation, the obtained mPPy@COF-Por can overcome Brownian motion achieves directional through self-thermophoretic force generated from PPy core. The enables to selectively recognize source lines reduces bio-adhesion biological medium, endowing with NIR light-powered good mobility. More importantly, such multifunctional integration allows COF-based be powerful nanoagent for treatment, high infrared thermal imaging/photoacoustic imaging/fluorescence trimodal imaging-guided combined photothermal/photodynamic therapeutic effect tumor successfully achieved. results offer considerable promise development COF imaging/therapy modalities biomedical applications.

Language: Английский

Citations

27

Recent progress of micro/nanomotors to overcome physiological barriers in the gastrointestinal tract DOI
Shuhao Zhang,

Chaoran Zhu,

Wanting Huang

et al.

Journal of Controlled Release, Journal Year: 2023, Volume and Issue: 360, P. 514 - 527

Published: July 12, 2023

Language: Английский

Citations

26

Swarming Multifunctional Heater–Thermometer Nanorobots for Precise Feedback Hyperthermia Delivery DOI
Jianfeng Liu,

Luolin Li,

Chuan Cao

et al.

ACS Nano, Journal Year: 2023, Volume and Issue: 17(17), P. 16731 - 16742

Published: Aug. 31, 2023

Micro-/nanorobots (MNRs) are envisioned to act as "motile-targeting" platforms for biomedical tasks due their ability propel and navigate in challenging, hard-to-reach biological environments. However, it remains a great challenge current swarming MNRs accurately report regulate therapeutic doses during disease treatment. Here we present the development of multifunctional heater-thermometer nanorobots (HT-NRs) application precise feedback photothermal hyperthermia delivery. The HT-NRs designed photothermal-responsive photonic nanochains consisting magnetic Fe3O4 nanoparticles arranged periodically one dimension encapsulated temperature-responsive hydrogel shell. exhibit energetic controllable motions under rotating field, while simultaneously functioning motile nanoheaters nanothermometers, utilizing conversion (photo)thermal-responsive structural color changes (photothermochromism). Consequently, can be quickly deployed remote target area (e.g., superficial tumor lesion) using collective motion selectively eliminate diseased cells specific targeted region by self-reporting photothermochromism visual precisely regulating external light irradiation. This work may inspire intelligent theranostic micro-/nanorobots practical applications

Language: Английский

Citations

18

Targeting biofilm infections in humans using small scale robotics DOI Creative Commons
Hong‐Huy Tran, Amanda Watkins, Min Jun Oh

et al.

Trends in biotechnology, Journal Year: 2023, Volume and Issue: 42(4), P. 479 - 495

Published: Nov. 13, 2023

The eradication of drug-resistant microbial biofilms remains an unresolved global health challenge. Small-scale robotics are providing innovative therapeutic and diagnostic approaches with high precision efficacy. These rapidly moving from proof-of-concept studies to translational biomedical applications using ex vivo, animal, clinical models. Here, we discuss the fundamental aspects how microrobots target infection sites disrupt structural functional traits their antimicrobial resistance mechanisms. We emphasize current mechanochemical disruption on-site drug delivery that supported by in vivo models preclinical testing, while also highlighting diagnostics potential. translation challenges provide perspectives for development microrobotics combat biofilm infections biofouling humans.

Language: Английский

Citations

17

Buoyancy‐Driven Micro/‐Nanomotors: From Fundamentals to Applications DOI
Ashish Kumar Shukla, Satyapriya Bhandari, Shirsendu Mitra

et al.

Small, Journal Year: 2024, Volume and Issue: 20(25)

Published: Jan. 15, 2024

Abstract The progression of self‐powered micro/‐nanomotors (MNMs) has rapidly evolved over the past few decades, showing applications in various fields such as nanotechnology, biomedical engineering, microfluidics, environmental science, and energy harvesting. Miniaturized MNMs transduce chemical/biochemical energies into mechanical motion for navigating through complex fluidic environments with directional control via external forces magnetic, photonic, electric stimuli. Among propulsion mechanisms, buoyancy‐driven have received noteworthy recognition due to their simplicity, efficiency, versatility. Buoyancy force‐driven motors harness principles density variation‐mediated force overcome resistance navigate environments. Restricting one direction helps movement, making it more efficient isotropic solutions. changes pH, ionic strength, chemical concentration, solute gradients, or presence specific molecules can influence evidenced by earlier reports. This review aims provide a fundamental detailed analysis current state‐of‐the‐art MNMs, aiming inspire further research innovation this promising field.

Language: Английский

Citations

7

Unlocking the Potential and Versatility of Quantum Dots: from Biomedical to Environmental Applications and Smart Micro/Nanorobots DOI Creative Commons
Martina Ussia, V. Privitera, Silvia Scalese

et al.

Advanced Materials Interfaces, Journal Year: 2024, Volume and Issue: 11(17)

Published: May 15, 2024

Abstract Quantum dots (QDs) are recognized as the most promising functional nanotechnology, for which its discoverers awarded Nobel Prize in 2023. Their remarkable tunability of optoelectronic properties has attracted significant interest from both researchers and industries, placing QDs at forefront developing cutting‐edge technologies. This comprehensive review aims to explore exciting results terms fundamental science, present forthcoming applications. Beyond their contributions biomedicine, energy, environmental quantum sensing, information processing, have brought important due integration into micro/nanorobotic systems, self‐propelled materials representing state art research micro nanoscale. These hybrid systems demonstrated noteworthy outcomes, unlocking novel possibilities accurately reviewed this article. In conclusion, addresses current challenges, offering insights facilitate further research, stimulate new developments, enhance comprehension full potential QDs.

Language: Английский

Citations

7

Temperature‐Sensitive Polymer‐Driven Nanomotors for Enhanced Tumor Penetration and Photothermal Therapy DOI

Beng Ma,

Ying Yu, Jiayi Li

et al.

Small, Journal Year: 2024, Volume and Issue: 20(46)

Published: Aug. 20, 2024

Abstract Self‐propelled nanomotors possess strong propulsion and penetration abilities, which can increase the efficiency of cellular uptake nanoparticles enhance their cytotoxicity against tumor cells, opening a new path for treating major diseases. In this study, concept driving by alternately stretching contracting temperature‐sensitive polymer (TS‐P) chain is proposed. The TS‐Ps are successfully linked to one side Cu 2‐x Se@Au (CS@Au) form Janus structure, designated as Se@Au‐polymer (CS@Au‐P) nanomotors. Under near‐infrared (NIR) light irradiation, Se generate photothermal effects that change system temperature, triggering alternation TS‐P structure mechanical force propels motion CS@Au‐P nanomotor significantly improved enhanced accumulation in tumor. Furthermore, exceptional conversion suggests potential nanomaterials therapy (PTT). prepared material exhibited good biocompatibility anti‐tumor both vivo vitro, providing research insights into design application therapy.

Language: Английский

Citations

5

Light-driven micro/nanomotors in biomedical applications DOI
Xuejiao Zeng, Mingzhu Yang, Hua Liu

et al.

Nanoscale, Journal Year: 2023, Volume and Issue: 15(46), P. 18550 - 18570

Published: Jan. 1, 2023

This review provides inspiration and promotes the clinical application of light-driven micro/nanomotors in biomedical field.

Language: Английский

Citations

12