International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138793 - 138793
Published: Dec. 1, 2024
Language: Английский
Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 35, P. 101894 - 101894
Published: Jan. 1, 2024
Language: Английский
Citations
36
European Polymer Journal, Journal Year: 2024, Volume and Issue: 206, P. 112800 - 112800
Published: Jan. 26, 2024
Language: Английский
Citations
24
Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)
Published: July 19, 2024
Abstract Colorectal cancer, the third most prevalent cancer globally, contributes significantly to mortality rates, with over 1.9 million reported cases and nearly 935,000 fatalities annually. Surgical resection is a primary approach for localized colorectal tumors, adjunct therapies like chemotherapy, radiotherapy, targeted/immunotherapy considered depending on tumor stage. However, despite preferences targeted immunotherapy post-surgery, chemotherapy remains commonly chosen due its lower cost high cancer-killing efficiency. Yet, faces issues such as resistance severe side effects. Nanotechnology has emerged in therapy by alleviating drawbacks of current treatment approaches. In past few decades, inorganic nanoparticles have shown promise combating offering advantages conventional chemotherapy. Compared organic nanoparticles, exhibit properties photosensitivity, conductivity, magnetic allure, thermal proficiency, allowing them function both drug carriers therapeutic agents. Derived primarily from carbon, silica, metals, metal oxides, they offer superior drug-loading capacity, heightened quantum yield, participation advanced photothermal photodynamic therapies. This review provides brief overview pathophysiology pivotal role therapy, delivery. Additionally, it discusses numerous based recent literature. Graphical abstract
Language: Английский
Citations
24
Current Pharmaceutical Design, Journal Year: 2024, Volume and Issue: 30(31), P. 2445 - 2467
Published: May 10, 2024
In recent years, the field of nanotechnology has brought about significant advancements that have transformed landscape disease diagnosis, prevention, and treatment, particularly in realm medical science. Among various approaches to nanoparticle synthesis, green synthesis method garnered increasing attention. Silver nanoparticles (AgNPs) emerged as noteworthy nanomaterials within spectrum metallic employed for biomedical applications. AgNPs possess several key attributes make them highly valuable field. They are biocompatible, cost-effective, environmentally friendly, rendering suitable bioengineering Notably, found a prominent role domain cancer diagnosis. Research investigations provided evidence AgNPs' anticancer activity, which involves mechanisms such DNA damage, cell cycle arrest, induction apoptosis, regulation specific cytokine genes. The primarily reduction silver ions by reducing agents. Interestingly, natural products living organisms proven be effective sources generation precursor materials used AgNP synthesis. This comprehensive review aims summarize aspects AgNPs, including their characterization, properties, biogenic Furthermore, highlights potential applications these combating cancer.
Language: Английский
Citations
8
International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 652, P. 123808 - 123808
Published: Jan. 14, 2024
Language: Английский
Citations
7
Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 97, P. 105755 - 105755
Published: May 30, 2024
Language: Английский
Citations
7
Artificial Cells Nanomedicine and Biotechnology, Journal Year: 2024, Volume and Issue: 52(1), P. 564 - 586
Published: Dec. 5, 2024
Cancer has a high rate of incidence and mortality throughout the world. Although several conventional approaches have been developed for treatment cancer, such as surgery, chemotherapy, radiotherapy thermal therapy, they remarkable disadvantages which result in inefficient cancer. For example, immunogenicity, prolonged treatment, non-specificity, metastasis cost are considered major drawbacks chemotherapy. Therefore, there is fundamental requirement development breakthrough technologies cancer suppression. Polysaccharide-based drug delivery systems (DDSs) most reliable carriers therapy. Polysaccharides, kind practical biomaterials, divided into types, including chitosan, alginates, dextran, hyaluronic acid, cyclodextrin, pectin, etc. Polysaccharides extracted from different natural resources (like herbal, marine, microorganisms, etc.). The potential features polysaccharides made them candidates therapeutics to sites; simple purification, ease modification functionalization, hydrophilicity, serum stability, appropriate loading capacity, biocompatibility, bioavailability, biodegradability stimuli-responsive sustained release manner considerable aspects these biopolymers. This review highlights applications polysaccharides-based DDSs pharmaceutical science
Language: Английский
Citations
7
CNS & Neurological Disorders - Drug Targets, Journal Year: 2024, Volume and Issue: 23(10), P. 1251 - 1262
Published: Feb. 14, 2024
Abstract: The potential of nanotechnology in advancing the diagnosis and treatment neurodegenerative diseases is explored this comprehensive literature review. findings these studies suggest that has capacity to improve existing therapeutic approaches, create novel safe compounds, develop more precise imaging techniques diagnostic methods for diseases. With emergence nanomedicine era, a new innovative approach diagnosing treating conditions been introduced. Notably, researchers' development nanocarrier drug delivery tool demonstrates immense compared conventional therapy, as it maximizes efficacy minimizes undesirable side effects.
Language: Английский
Citations
5
European Polymer Journal, Journal Year: 2024, Volume and Issue: 209, P. 112924 - 112924
Published: March 11, 2024
Language: Английский
Citations
4
Current Pharmaceutical Design, Journal Year: 2024, Volume and Issue: 31(4), P. 244 - 260
Published: April 30, 2024
In recent years, advancements in chemistry have allowed the tailoring of materials at nanoscopic level as needed. There are mainly four main types nanomaterials used drug carriers:metal-based nanomaterials, organic inorganic and polymer nanomaterials. The a carrier showed advantages for decreased side effects with higher therapeutic index. stability compounds increased by encapsulation within nano-drug carriers, leading to systemic toxicity. Nano-drug carriers also controlled release system-made solubility characteristics nanoparticles surface coating surfactants. review focuses on different nanoparticle synthesis process, techniques purposes, applications prospects biomedical applications.
Language: Английский
Citations
4