A review of biomaterial degradation assessment approaches employed in the biomedical field DOI Creative Commons
Hillary Mndlovu, Pradeep Kumar,

Lisa C. du Toit

et al.

npj Materials Degradation, Journal Year: 2024, Volume and Issue: 8(1)

Published: July 6, 2024

Abstract The biological response to biomaterials plays a crucial role in selecting suitable materials for the formulation and development of tissue engineering platforms. Biodegradation is one properties that considered appropriate biomedical applications. process breaking down large molecules into smaller with/without aid catalytic enzymes. biodegradation chemical absorption, distribution, metabolism, excretion, toxicity (ADMET) small body. Degradation can be followed by assessing physical, mechanical, attributes biomaterials. There are several techniques/parameters targeted when studying degradation biomaterials, with gravimetric analysis, surface erosion, morphological changes being largely employed techniques. However, techniques present few limitations, such as technical errors material solubility mistaken degradation, these infer but not confirm they do provide composition fragmenting/fragmented molecules. American Society Testing Materials (ASTM) guidelines parameters biodegradation. ASTM assessment approaches need updated sufficient evidence draw conclusive decisions regarding In this review, critically reviewed about their advantages disadvantages, suggestions on how still play This review could assist researchers employ cost-effective, efficient, multiple evaluate information Suggested future should include measuring (such chemical, or physical biomaterials) real-time, employing non-invasive, continuous, automated processes.

Language: Английский

Multifunctional Flexible Humidity Sensor Systems Towards Noncontact Wearable Electronics DOI Creative Commons
Yuyao Lu, Geng Yang, Yajing Shen

et al.

Nano-Micro Letters, Journal Year: 2022, Volume and Issue: 14(1)

Published: July 22, 2022

In the past decade, global industry and research attentions on intelligent skin-like electronics have boosted their applications in diverse fields including human healthcare, Internet of Things, human-machine interfaces, artificial intelligence soft robotics. Among them, flexible humidity sensors play a vital role noncontact measurements relying unique property rapid response to change. This work presents an overview recent advances using various active functional materials for contactless monitoring. Four categories are highlighted based resistive, capacitive, impedance-type voltage-type working mechanisms. Furthermore, typical strategies chemical doping, structural design Joule heating introduced enhance performance sensors. Drawing perception capability, human/plant healthcare management, interactions as well integrated sensor-based feedback systems presented. The burgeoning innovations this field will benefit society, especially during COVID-19 epidemic, where cross-infection should be averted sensation is highly desired.

Language: Английский

Citations

216
Bone Tissue Engineering Scaffolds: Function of Multi‐Material Hierarchically Structured Scaffolds DOI Creative Commons

Tejas M. Koushik,

Catherine Miller, Elsa Antunes

et al.

Advanced Healthcare Materials, Journal Year: 2022, Volume and Issue: 12(9)

Published: Dec. 13, 2022

Bone tissue engineering (BTE) is a topic of interest for the last decade, and advances in materials, processing techniques, understanding bone healing pathways have opened new avenues research. The dual responsibility BTE scaffolds providing load-bearing capability interaction with local extracellular matrix to promote challenge synthetic scaffolds. This article describes usage multi-materials hierarchical structures mimic structure natural tissues function as bioactive first part this literature review physiology responses interactions at different stages repair. following section reviews available on biomaterials used followed by some multi-material approaches. next discusses impact scaffold's structural features necessity distribution scaffold structure. Finally, highlights emerging trends developments that can inspire strategies truly develop generation

Language: Английский

Citations

148
Recent advances in biodegradable polymers – Properties, applications and future prospects DOI
Chandrapaul Mukherjee,

Dissa Varghese,

J.S. Krishna

et al.

European Polymer Journal, Journal Year: 2023, Volume and Issue: 192, P. 112068 - 112068

Published: April 10, 2023

Language: Английский

Citations

143
New perspectives: In-situ tissue engineering for bone repair scaffold DOI

Shujun Cao,

Yao Zhao, Yimin Hu

et al.

Composites Part B Engineering, Journal Year: 2020, Volume and Issue: 202, P. 108445 - 108445

Published: Oct. 1, 2020

Language: Английский

Citations

140
Biodegradable electrospinning superhydrophilic nanofiber membranes for ultrafast oil-water separation DOI Creative Commons
Xiquan Cheng, Tongyu Li, Linlin Yan

et al.

Science Advances, Journal Year: 2023, Volume and Issue: 9(34)

Published: Aug. 23, 2023

Although membrane technology has attracted considerable attention for oily wastewater treatment, the plastic waste generated from discarded membranes presents an immediate challenge achieving eco-friendly separation. We designed on-demand biodegradable superhydrophilic composed of polylactic acid nanofibers in conjunction with polyethylene oxide hydrogels using electrospinning ultrafast purification water. Our results showed that use increased number hydrogen bonds formed between surface and water molecules by 357.6%. This converted hydrophobic into ones, which prevented fouling accelerated emulsion penetration through membranes. The oil-in-water permeance our newly nanofiber 61.9 times (2.1 × 104 liters per square meter hour bar) separation efficiency >99.6%, was superior to state-of-the-art Moreover, formation found accelerate biodegradation lactic over 30%, offering a promising approach treatment.

Language: Английский

Citations

91
Into the Tissues: Extracellular Matrix and Its Artificial Substitutes: Cell Signalling Mechanisms DOI Creative Commons
Aleksandra Bandzerewicz, Agnieszka Gadomska‐Gajadhur

Cells, Journal Year: 2022, Volume and Issue: 11(5), P. 914 - 914

Published: March 7, 2022

The existence of orderly structures, such as tissues and organs is made possible by cell adhesion, i.e., the process which cells attach to neighbouring a supporting substance in form extracellular matrix. matrix three-dimensional structure composed collagens, elastin, various proteoglycans glycoproteins. It storehouse for multiple signalling factors. Cells are informed their correct connection via receptors. Tissue disruption often prevents natural reconstitution use appropriate implants then required. This review compilation crucial information on structural functional features complex mechanisms cell–cell connectivity. possibilities regenerating damaged using an artificial substitute described, detailing host response implant. An important issue surface properties implant modification.

Language: Английский

Citations

72
Multimaterial 3D printing of self-assembling smart thermo-responsive polymers into 4D printed objects: A review DOI Creative Commons
Mahdiyar Shahbazi,

Henry Jäger,

Rammile Ettelaie

et al.

Additive manufacturing, Journal Year: 2023, Volume and Issue: 71, P. 103598 - 103598

Published: May 9, 2023

The three-dimensional (3D) printing and its extension four-dimensional (4D) technique show great promise for advanced additive manufacturing of functional architected materials with engineered micro- nanoscale features. actual usage to produce 3D/4D structures is primarily dependent on the improvement printable polymeric inks. Thermoresponsive polymers (TRPs) broad application prospects in since they enable changing physicochemical properties system at a specific temperature. Continuing progress understanding TRP phenomena design new feedstocks their compatibility fabrication processes. Therefore, increasing overlap between fields fundamental TRPs application-based research efforts can be important emerging technology. In this review, we provide an overview TRPs, different classes 3D printing, ranging from biosensors via self-assembly variety biofabrication, biomedical, biotechnology, food applications. Basic knowledge imperative processes like gelation mechanisms bio-based adsorption surfaces adhesion, strategies using also provided. For diverse synthesis basic physical chemical features are described mechanism behavior highlighted. Fabrication methods have been discussed describing several detail.

Language: Английский

Citations

70
Inorganic/organic combination: Inorganic particles/polymer composites for tissue engineering applications DOI Creative Commons
Astha Sharma, Ganesh R. Kokil, Yan He

et al.

Bioactive Materials, Journal Year: 2023, Volume and Issue: 24, P. 535 - 550

Published: Jan. 11, 2023

Biomaterials have ushered the field of tissue engineering and regeneration into a new era with development advanced composites. Among these, composites inorganic materials organic polymers present unique structural biochemical properties equivalent to naturally occurring hybrid systems such as bones, thus are highly desired. The last decade has witnessed steady increase in research on focus being mimicking peculiar inorganic/organic combination nature. In this review, we discuss recent progress use particle/polymer for regenerative medicine. We elaborated advantages over their particle-based composite counterparts. As particles play crucial role defining features capacity composites, review puts special emphasis various types used that covered categorised two broad (1) solid (e.g

Language: Английский

Citations

55
Degradable biomedical elastomers: paving the future of tissue repair and regenerative medicine DOI
Ben Jia,

Heyuan Huang,

Zhicheng Dong

et al.

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(8), P. 4086 - 4153

Published: Jan. 1, 2024

This review critically analyzes degradable biomedical elastomers, focusing on their degradation, synthesis, microstructure, and role in tissue repair. It guides experts balancing degradation with repair for improved applications.

Language: Английский

Citations

49
Designing biomimetic scaffolds for skin tissue engineering DOI

Jiatian Chen,

Yingwei Fan,

Guozhao Dong

et al.

Biomaterials Science, Journal Year: 2023, Volume and Issue: 11(9), P. 3051 - 3076

Published: Jan. 1, 2023

This review offers systematic considerations of material design principles and fabrication techniques for biomimetic skin tissue engineering scaffolds.

Language: Английский

Citations

45