Polymer, Journal Year: 2024, Volume and Issue: unknown, P. 127720 - 127720
Published: Oct. 1, 2024
Language: Английский
Advanced Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 2, 2025
High transductive loss at tissue injury sites impedes repair. The high dissipation characteristics in the electromechanical conversion of piezoelectric biomaterials pose a challenge. Therefore, supramolecular engineering and microfluidic technology is utilized to introduce slide-ring polyrotaxane conductive polypyrrole construct stress-electric coupling hydrogel microspheres. molecular slippage mechanism structure stores releases mechanical energy, reducing loss, barium titanate enables stress-electricity conversion, conjugated π-electron movement network improves internal electron transfer efficiency microspheres, thereby for first time. Compared traditional low-dissipation microspheres increased by 2.3 times, energy decreased 43%. At cellular level, electrical signals generated triggered Ca
Language: Английский
Citations
1
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160726 - 160726
Published: Feb. 1, 2025
Language: Английский
Citations
1
Science China Materials, Journal Year: 2025, Volume and Issue: unknown
Published: March 10, 2025
Language: Английский
Citations
1
ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(10), P. 11037 - 11052
Published: May 15, 2024
Diabetic wound infection has always been a huge threat to human's healthcare, and most of the existing therapies have reduced efficacy, drug resistance toxic side effects. Therefore, there is an urgent need develop innovative therapeutic strategies for diabetic management. At present, intelligence stimulus-responsive bioactive hydrogels in healing received extensive attention. This mainly reflected on-demand release active substances response physical, chemical or biological stimuli. paper focuses on potential various their applications healing, briefly discusses factors slow preparation methods smart hydrogels. Finally, future development further management wounds presented.
Language: Английский
Citations
7
Journal of Bioresources and Bioproducts, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
0
Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 13, 2025
Abstract Senescent bone tissue displays a pathological imbalance characterized by decreased angiogenesis, disrupted bioelectric signaling, ion dysregulation, and reduced stem cell differentiation. Once defects occur, this makes them difficult to repair. An innovative synergistic therapeutic strategy is utilized reverse these imbalances via conductive hydrogel doped with magnesium (Mg 2+ )‐modified black phosphorus (BP). The reprograms electrical signals, restores Mg homeostasis, reconstructs physiological promotes blood vessel regeneration in senile defects. synergistically both the chemical signals within microenvironment. This increases expression of vascular endothelial growth factor (VEGF) VEGF receptor‐2 (VEGFR2), activates PI3K‐AKT‐eNOS pathway, significantly angiogenic ability cells aged state. In addition, normalizes calcium (Ca ) influx, accumulation osteogenic transcription factors nucleus, differentiation senescent cells. treatment bone‐vascular coupling areas defects, achieves effective vascularized regeneration, has good potential for
Language: Английский
Citations
0
Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 99 - 108
Published: Jan. 1, 2025
Language: Английский
Citations
0
Light Science & Applications, Journal Year: 2025, Volume and Issue: 14(1)
Published: May 14, 2025
Abstract By introducing piezoelectric materials into hydrogel oral dressings, a microelectric field could be generated under stress stimulation, thus facilitating wound healing. However, to adapt the moist and dynamic environment of cavity, traditional “step-by-step” synthesis often requires combination with different functionalities. Given property differences between these materials, this strategy typically involves complex experimental procedures unnecessary energy consumption. In study, concept “integrated construction”, we innovatively proposed dual-step photo-induced method successfully fabricated composite hydrogels excellent performance. We introduced abundant oxygen vacancies ZnO, leveraging enhanced interface dynamics achieve sustained effect. With double-network polymer framework as template, spontaneous in-situ polydopamine (PDA) within without any extra special conditions operation procedures. conducted thorough analysis mechanism underlying applied as-prepared for treatment wounds, which significantly accelerated healing process due outstanding comprehensive performance hydrogel. These results suggest novel ideas theoretical support facile construction high-performance based on photodynamic principles, demonstrating immense potential future applications in dressings.
Language: Английский
Citations
0
Materials Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 8(18), P. 2944 - 2977
Published: Jan. 1, 2024
Conductive hydrogels, with their electrical stimulation effects and properties, are potential candidates for treating diabetic wounds.
Language: Английский
Citations
3
Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
In this work, we proposed a mechanism for hydrogel-based dressings to respond endogenous electric fields through exudate absorption and conducted verification study using polyacrylamide sodium alginate (PAM–SA) hydrogels.
Language: Английский
Citations
3