A Biomimetic One‐Stone‐Two‐Birds Hydrogel with Electroconductive, Photothermally Antibacterial and Bioadhesive Properties for Skin Tissue Regeneration and Mechanosensation Restoration DOI Open Access
Hua Wei, Houchao Jing, Can Cheng

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 13, 2024

Abstract Severe skin wounds arising from burns, cancers, and accidents can damage the entire tissue structure, resulting in permanent somatosensory dysfunction patients. Although emerging hydrogel dressings have shown clinical potential for accelerating wound repair, use of an individual material to synchronously restore structure sensory function defective remains a challenge. Herein, multifunctional that combines electroconductive polydopamine‐capped graphene nanosheets (PrGOs) embedded dynamically crosslinked dual‐polysaccharide (xyloglucan chitosan) matrix network is presented. The fabricated hydrogels adjustable modulus be matched at site, owing dynamic Schiff‐based crosslinking as well facile photo‐triggered secondary crosslinking. Furthermore, photothermal activity PrGO elevate local temperature up ≈50 °C, significantly restraining bacterial growth. These two factors jointly promote regeneration tissue. Tissue adhesion also reported offers conformable robust interface detect quantify human movement physiological signals mimic system. This effective one‐stone‐for‐two‐birds simultaneously achieves multi‐signal sensing, promoting restoration and/or replacement damaged skins.

Language: Английский

Intrinsic immunomodulatory hydrogels for chronic inflammation DOI

Yuna Qian,

Jiayi Ding,

Rui Zhao

et al.

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

This tutorial review presents the development of advanced immunomodulatory hydrogels strategically designed to address chronic inflammation through their intrinsic properties.

Language: Английский

Citations

9

Sandwich‐Structured Organogel with Asymmetric‐Adhesion and Adaptive Optical Regulation for Simultaneous Sensing of Human Motion and Temperature Without Interference DOI Open Access

Sijia Ge,

Shinian Liu,

Ying Kong

et al.

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 3, 2025

Abstract The application of these NIPAm‐based temperature‐sensitive hydrogels in wearable sensing is limited by the inability to achieve a long‐lasting temperature response and adaptive optical regulation due water loss hydrogel, avoid phenomenon detachment external touch, mutual interference between stress signals. Here, sandwich‐structured organogel sensors (SOGS) are prepared based on solvent modulation interfacial fusion cross‐linking strategies asymmetric‐adhesion, regulation, simultaneous human motion without Modulation properties through hydrogen bonding glycol amide groups for long‐term (10–30 °C) infrared ultraviolet regulation. Adhesive conductive introduced under an strategy unilateral adhesion (67.28 kPa pig skin) sensing. intermediate layer prevents In conclusion, provides new idea developing novel responsive gels, facile method unilaterally adherent, interference‐resistant, multifunctional sensors.

Language: Английский

Citations

1

A review of recent advances in drug loading, mathematical modeling and applications of hydrogel drug delivery systems DOI
Xiaohan Hu,

Chenyun Zhang,

Yingshuo Xiong

et al.

Journal of Materials Science, Journal Year: 2024, Volume and Issue: 59(32), P. 15077 - 15116

Published: Aug. 1, 2024

Language: Английский

Citations

7

Macromolecular Poly(N‐isopropylacrylamide) (PNIPAM) in Cancer Treatment and Beyond DOI Creative Commons

Siddhi Throat,

Sankha Bhattacharya

Advances in Polymer Technology, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

Poly(N‐isopropylacrylamide) (PNIPAM) is a versatile polymer known for its phase transition properties, exhibiting lower critical solution temperature (LCST) of approximately 32°C. Below this temperature, PNIPAM hydrophilic, while above it, the becomes hydrophobic, making it ideal thermosensitive drug delivery systems (DDSs). In tissue engineering, provides biocompatible, nontoxic and stimuli‐responsive surface cell culture. Its nature ensures safety in medical applications. enhances biosensing diagnostics through affinity biomolecules, improving accuracy. Widely used hydrogels, smart textiles, soft robotics various applications, adapts to environmental changes. straightforward synthesis allows creation diverse copolymers composites, applicable selective reactions conjugations with fluorescent tags or chemical modifications. PNIPAM’s versatility extends pH‐responsive alternatives, broadening application spectrum. Practical examples include separation water treatment cleaning processes. This discussion explores biomedical particularly cancer treatment, photothermal therapy (PTT) photodynamic (PDT), gene imaging. Additionally, highlights noncancerous such as small interfering RNA (siRNA) targeting oncogenes detailed imaging deep tumour tissues.

Language: Английский

Citations

7

Nanomedicines as a cutting-edge solution to combat antimicrobial resistance DOI Creative Commons
Raghu Solanki, Nilesh Makwana, Rahul Kumar

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(45), P. 33568 - 33586

Published: Jan. 1, 2024

Antimicrobial mechanism of nanomaterials to combat AMR.

Language: Английский

Citations

5

A universal strategy to prepare reversible bacteria-killing and bacteria-releasing textiles with nice antifouling ability for long-term service via LBL assembly of modified CMC DOI Creative Commons
Xue Yang,

Yunhui Xu,

Lu Cai

et al.

Industrial Crops and Products, Journal Year: 2025, Volume and Issue: 225, P. 120463 - 120463

Published: Jan. 11, 2025

Language: Английский

Citations

0

External Stimuli-Driven Catalytic Hydrogels for Biomedical Applications DOI
Jing Liao,

Jing-Xi Sun,

Wencong Jia

et al.

Chemical Communications, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

This review discusses design strategies for external stimuli-driven hydrogels with in situ catalytic processes. It highlights precise control over the properties, elucidating regulatory mechanisms and deepening understanding of applications.

Language: Английский

Citations

0

Material Design, Fabrication Strategies, and the Development of Multifunctional Hydrogel Composites Dressings for Skin Wound Management DOI
Zhibin Wu, Dongdong Lu, Shuo Sun

et al.

Biomacromolecules, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 17, 2025

The skin is fragile, making it very vulnerable to damage and injury. Untreated wounds can pose a serious threat human health. Three-dimensional polymer network hydrogels have broad application prospects in wound dressings due their unique properties structure. therapeutic effect of traditional limited, while multifunctional composite show greater potential. Multifunctional regulate moisture through formula adjustment. Moreover, be combined with bioactive ingredients improve performance healing applications. Stimulus-responsive respond specifically the environment meet needs different stages. This review summarizes material types, structure, properties, design considerations, formulation strategies for hydrogel used healing. We discuss various types recently developed dressings, highlights importance tailoring physicochemical addresses potential challenges preparing dressings.

Language: Английский

Citations

0

PhotoChem Interplays: Lighting the Way for drug delivery and diagnosis DOI
Asmita Banstola, Zuan‐Tao Lin, Yongli Li

et al.

Advanced Drug Delivery Reviews, Journal Year: 2025, Volume and Issue: 219, P. 115549 - 115549

Published: Feb. 20, 2025

Language: Английский

Citations

0

Preparation schemes and applications of multifunctional PVA composite hydrogels DOI
Yunge Liu, Jing Zhang, Dianyu Wang

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160946 - 160946

Published: Feb. 1, 2025

Language: Английский

Citations

0