Lab on a Chip, Journal Year: 2023, Volume and Issue: 23(6), P. 1432 - 1466
Published: Jan. 1, 2023
Representation of the influence biological and nanoscale factors on protein corona conformation function in a healthy versus pathogenic environment.
Language: Английский
Chemical Society Reviews, Journal Year: 2023, Volume and Issue: 52(6), P. 2031 - 2081
Published: Jan. 1, 2023
Bioactive materials are a special class of biomaterials that can react in vivo to induce biological response or regulate functions, thus achieving better curative effect than traditional inert biomaterials. For cancer theranostics, compared with organic polymer nanomaterials, inorganic nanomaterials possess unique physical and chemical properties, have stronger mechanical stability on the basis maintaining certain bioactivity, easy be compounded various carriers (polymer carriers, etc.), so as achieve specific antitumor efficacy. After entering nanoscale, due nano-size effect, high surface area nanostructures, exhibit effects, which significantly influence interaction organisms. Therefore, research applications bioactive theranostics attracted wide attention. In this review, we mainly summarize recent progress also introduce definition, synthesis modification strategies nanomaterials. Thereafter, tumor imaging therapy, including microenvironment (TME) regulation, catalytic gas regulatory cell death immunotherapy, discussed. Finally, biosafety challenges mentioned, their future development opportunities prospected. This review highlights bioapplication
Language: Английский
Citations
125
Advanced Drug Delivery Reviews, Journal Year: 2022, Volume and Issue: 190, P. 114536 - 114536
Published: Sept. 13, 2022
Language: Английский
Citations
108
Advanced Science, Journal Year: 2021, Volume and Issue: 9(2)
Published: Nov. 19, 2021
Cancer is one of the top life-threatening dangers to human survival, accounting for over 10 million deaths per year. Bioactive glasses have developed dramatically since their discovery 50 years ago, with applications that include therapeutics as well diagnostics. A new system within bioactive glass family, mesoporous (MBGs), has evolved into a multifunctional platform, thanks MBGs easy-to-functionalize nature and tailorable textural properties-surface area, pore size, volume. Although yet meet potential in tumor treatment imaging practice, recently research shed light on distinguished capabilities promising theranostic systems cancer therapy. This review presents progress field MBG diagnosis therapy, including synthesis MBGs, mechanistic overview application drug monitoring, therapy ( particularly, targeted delivery stimuli-responsive nanoplatforms), immunological profile MBG-based nanodevices reference development novel therapeutics.
Language: Английский
Citations
105
ACS Nano, Journal Year: 2022, Volume and Issue: 16(7), P. 10066 - 10087
Published: July 1, 2022
Antibiotic resistance has become a serious threat to human health due the overuse of antibiotics. Different antibiotics are being developed treat resistant bacteria, but development cycle is hard keep up with high incidence antibiotic resistance. Recent advances in antimicrobial nanomaterials have made nanotechnology powerful solution this dilemma. Among these nanomaterials, gold excellent antibacterial efficacy and biosafety, making them alternatives This review presents strategies that use combat drug-resistant bacteria. We focus on influence physicochemical factors such as surface chemistry, size, shape their properties describe applications medical devices. Finally, existing challenges future directions discussed.
Language: Английский
Citations
105
Lab on a Chip, Journal Year: 2023, Volume and Issue: 23(6), P. 1432 - 1466
Published: Jan. 1, 2023
Representation of the influence biological and nanoscale factors on protein corona conformation function in a healthy versus pathogenic environment.
Language: Английский
Citations
101