Recent Advances in Transparent Electrodes and Their Multimodal Sensing Applications DOI Creative Commons
Majed Althumayri, Ritu Das, Ramu Banavath

et al.

Advanced Science, Journal Year: 2024, Volume and Issue: 11(38)

Published: Aug. 9, 2024

This review examines the recent advancements in transparent electrodes and their crucial role multimodal sensing technologies. Transparent electrodes, notable for optical transparency electrical conductivity, are revolutionizing sensors by enabling simultaneous detection of diverse physical, chemical, biological signals. Materials like graphene, carbon nanotubes, conductive polymers, which offer a balance between transparency, mechanical flexibility, at forefront this development. These integral various applications, from healthcare to solar cell technologies, enhancing sensor performance complex environments. The paper addresses challenges applying these such as need high optoelectronic performance, biocompatibility. It explores new materials innovative techniques overcome hurdles, aiming broaden capabilities devices. provides comparative analysis different electrode materials, discussing applications ongoing development novel systems sensing. exploration offers insights into future highlighting transformative potential bioelectronics

Language: Английский

Technology Roadmap for Flexible Sensors DOI Creative Commons
Yifei Luo, Mohammad Reza Abidian, Jong‐Hyun Ahn

et al.

ACS Nano, Journal Year: 2023, Volume and Issue: 17(6), P. 5211 - 5295

Published: March 9, 2023

Humans rely increasingly on sensors to address grand challenges and improve quality of life in the era digitalization big data. For ubiquitous sensing, flexible are developed overcome limitations conventional rigid counterparts. Despite rapid advancement bench-side research over last decade, market adoption remains limited. To ease expedite their deployment, here, we identify bottlenecks hindering maturation propose promising solutions. We first analyze achieving satisfactory sensing performance for real-world applications then summarize issues compatible sensor-biology interfaces, followed by brief discussions powering connecting sensor networks. Issues en route commercialization sustainable growth sector also analyzed, highlighting environmental concerns emphasizing nontechnical such as business, regulatory, ethical considerations. Additionally, look at future intelligent sensors. In proposing a comprehensive roadmap, hope steer efforts towards common goals guide coordinated development strategies from disparate communities. Through collaborative efforts, scientific breakthroughs can be made sooner capitalized betterment humanity.

Language: Английский

Citations

710

Perspectives on recent advancements in energy harvesting, sensing and bio-medical applications of piezoelectric gels DOI Creative Commons
Thangavel Vijayakanth, Sudha Shankar, Gal Finkelstein-Zuta

et al.

Chemical Society Reviews, Journal Year: 2023, Volume and Issue: 52(17), P. 6191 - 6220

Published: Jan. 1, 2023

This review highlights the recent progress in piezoelectric gels (also known as PiezoGels) comprised of polymers, ceramic oxides and supramolecular materials used for energy harvesting, sensing wound dressing.

Language: Английский

Citations

66

Smart Contact Lenses for Healthcare Monitoring and Therapy DOI
Xiaohu Liu, Ying Ye, Yuancai Ge

et al.

ACS Nano, Journal Year: 2024, Volume and Issue: 18(9), P. 6817 - 6844

Published: Feb. 26, 2024

The eye contains a wealth of physiological information and offers suitable environment for noninvasive monitoring diseases via smart contact lens sensors. Although extensive research efforts recently have been undertaken to develop sensors, they are still in an early stage being utilized as intelligent wearable sensing platform various biophysical/chemical conditions. In this review, we provide general introduction lenses that developed disease therapy. First, different biomarkers available from the ocular summarized, including both physical chemical biomarkers, followed by commonly used materials, manufacturing processes, characteristics lenses. Smart eye-drug delivery with advancing technologies achieve more efficient treatments then introduced well latest developments diagnosis. Finally, sensor communication antimicrobial other emerging bioapplications also discussed challenges prospects future development

Language: Английский

Citations

33

Wireless Battery-free and Fully Implantable Organ Interfaces DOI
A. K. Bhatia, Jessica Hanna, Tucker Stuart

et al.

Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(5), P. 2205 - 2280

Published: Feb. 21, 2024

Advances in soft materials, miniaturized electronics, sensors, stimulators, radios, and battery-free power supplies are resulting a new generation of fully implantable organ interfaces that leverage volumetric reduction mechanics by eliminating electrochemical storage. This device class offers the ability to provide high-fidelity readouts physiological processes, enables stimulation, allows control over organs realize therapeutic diagnostic paradigms. Driven seamless integration with connected infrastructure, these devices enable personalized digital medicine. Key advances carefully designed material, electrophysical, electrochemical, electromagnetic systems form implantables mechanical properties closely matched target deliver functionality supports sensors stimulators. The elimination operation, anywhere from acute, lifetimes matching subject physical dimensions imperceptible operation. review provides comprehensive overview basic building blocks related topics such as implantation, delivery, sterilization, user acceptance. State art examples categorized system an outlook interconnection advanced strategies for computation leveraging consistent influx elevate this current battery-powered is highlighted.

Language: Английский

Citations

19

Self‐Lubricating, Living Contact Lenses DOI Creative Commons
María Puertas‐Bartolomé,

Izabook Gutiérrez‐Urrutia,

Lara Luana Teruel‐Enrico

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(27)

Published: April 7, 2024

Abstract The increasing prevalence of dry eye syndrome in aging and digital societies compromises long‐term contact lens (CL) wear forces users to regular drop instillation alleviate discomfort. Here a novel approach with the potential improve extend lubrication properties CLs is presented. This achieved by embedding lubricant‐secreting biofactories within CL material. self‐replenishable reservoirs autonomously produce release hyaluronic acid (HA), natural wetting agent, long term. hydrogel matrix regulates growth HA production, allows diffusion nutrients for at least 3 weeks. continuous sustainably reduces friction coefficient surface. A self‐lubricating prototype presented, where functional are contained ring periphery, outside vision area. device cytocompatible fulfils physicochemical requirements commercial CLs. fabrication process compatible current manufacturing processes correction. It envisioned that durable‐by‐design living could enable comfort minimize need lubricating drops.

Language: Английский

Citations

17

Photonic Nanomaterials for Wearable Health Solutions DOI Creative Commons
Taewoong Park, Jung Woo Leem, Young L. Kim

et al.

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 3, 2025

Abstract This review underscores the transformative potential of photonic nanomaterials in wearable health technologies, driven by increasing demands for personalized monitoring. Their unique optical and physical properties enable rapid, precise, sensitive real‐time monitoring, outperforming conventional electrical‐based sensors. Integrated into ultra‐thin, flexible, stretchable formats, these materials enhance compatibility with human body, enabling prolonged wear, improved efficiency, reduced power consumption. A comprehensive exploration is provided integration devices, addressing material selection, light‐matter interaction principles, device assembly strategies. The highlights critical elements such as form factors, sensing modalities, data communication, representative examples skin patches contact lenses. These devices precise monitoring management biomarkers diseases or biological responses. Furthermore, advancements approaches have paved way continuum care systems combining multifunctional sensors therapeutic drug delivery mechanisms. To overcome existing barriers, this outlines strategies design, engineering, system integration, machine learning to inspire innovation accelerate adoption next‐generation health, showcasing their versatility digital applications.

Language: Английский

Citations

3

Wireless Non‐Invasive Monitoring of Cholesterol Using a Smart Contact Lens DOI Creative Commons
Hayoung Song, Haein Shin, Hunkyu Seo

et al.

Advanced Science, Journal Year: 2022, Volume and Issue: 9(28)

Published: Aug. 17, 2022

Abstract Herein, a wireless and soft smart contact lens that enables real‐time quantitative recording of cholesterol in tear fluids for the monitoring patients with hyperlipidemia using smartphone is reported. This incorporates an electrochemical biosensor continuous detection concentrations, stretchable antenna, integrated circuits communication, which makes only device required to operate this remotely without obstructing wearer's vision. The rabbit model utilized confirm correlation between levels fluid blood feasibility diagnostic application cholesterol‐related diseases. Further vivo tests human subjects demonstrated its good biocompatibility, wearability, reliability as non‐invasive healthcare device.

Language: Английский

Citations

66

A CRISPR-Cas12a integrated SERS nanoplatform with chimeric DNA/RNA hairpin guide for ultrasensitive nucleic acid detection DOI Creative Commons
Bohan Yin, Qin Zhang,

Xinyue Xia

et al.

Theranostics, Journal Year: 2022, Volume and Issue: 12(13), P. 5914 - 5930

Published: Jan. 1, 2022

CRISPR-Cas12a has been integrated with nanomaterial-based optical techniques, such as surface-enhanced Raman scattering (SERS), to formulate a powerful amplification-free nucleic acid detection system. However, nanomaterials impose steric hindrance limit the accessibility of narrow gaps (SERS hot spots) among nanoparticles (NPs) for producing significant change in signals after detection.

Language: Английский

Citations

56

Soft Bioelectronics for Therapeutics DOI
Zongman Zhang,

Zhongtai Zhu,

Pengcheng Zhou

et al.

ACS Nano, Journal Year: 2023, Volume and Issue: 17(18), P. 17634 - 17667

Published: Sept. 7, 2023

Soft bioelectronics play an increasingly crucial role in high-precision therapeutics due to their softness, biocompatibility, clinical accuracy, long-term stability, and patient-friendliness. In this review, we provide a comprehensive overview of the latest representative therapeutic applications advanced soft bioelectronics, ranging from wearable for skin wounds, diabetes, ophthalmic diseases, muscle disorders, other diseases implantable against complex such as cardiac arrhythmias, cancer, neurological others. We also highlight key challenges opportunities future translation commercialization toward personalized medicine.

Language: Английский

Citations

39

TFOS Lifestyle: Impact of contact lenses on the ocular surface DOI Open Access
Lyndon Jones, Nathan Efron, Kalika Bandamwar

et al.

The Ocular Surface, Journal Year: 2023, Volume and Issue: 29, P. 175 - 219

Published: May 4, 2023

Language: Английский

Citations

38