Journal of Materials Chemistry B, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
A new class of ultrasound-induced piezoionic hydrogels with antibacterial and antioxidant properties are developed to accelerate infected diabetic wound healing.
Language: Английский
Signal Transduction and Targeted Therapy, Journal Year: 2024, Volume and Issue: 9(1)
Published: July 1, 2024
The applications of hydrogels have expanded significantly due to their versatile, highly tunable properties and breakthroughs in biomaterial technologies. In this review, we cover the major achievements potential therapeutic applications, focusing primarily on two areas: emerging cell-based therapies promising non-cell modalities. Within context cell therapy, discuss capacity overcome existing translational challenges faced by mainstream therapy paradigms, provide a detailed discussion advantages principal design considerations for boosting efficacy as well list specific examples different disease scenarios. We then explore drug delivery, physical intervention therapies, other areas (e.g., bioadhesives, artificial tissues, biosensors), emphasizing utility beyond mere delivery vehicles. Additionally, complement our latest progress clinical application outline future research directions, particularly terms integration with advanced biomanufacturing This review aims present comprehensive view critical insights into selection both tailored meet requirements diverse diseases situations.
Language: Английский
Citations
83
Advanced Materials Technologies, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 22, 2025
Abstract Development of an antiadhesion polypropylene (PP) mesh in hernia repair is a recognized need because its efficacy limited by severe abdominal adhesions. The porous structure PP can facilitate the integration between prosthetic material and tissue promote wall defect. Herein, composite hydrogel coating composed polyvinyl alcohol (PVA) hyaluronic acid methacrylate (HAMA) fabricated on surface through ultraviolet photopolymerization combined with freezing–thawing method. resulted coated retain 43.33% pore this way. In vitro tests proved as‐prepared exhibit excellent hydrophilicity biocompatibility. Meanwhile, shows good stability phosphate buffered saline medium. After implantation rat defect model, modified effectively prevents formation adhesion reducing inflammatory response suppressing excessive deposition collagen fiber. Immunohistochemical staining results demonstrate that not only decrease expression IL‐6, TNF‐α, CD68 but also CD31. Thus, type preventing postoperative adhesions improving angiogenesis may be promising clinical material.
Language: Английский
Citations
2
Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 29, 2025
Abstract With the increasing demand in fields such as wearable sensors, soft robotics, tissue engineering, and wound dressings, development of hydrogels with strong adhesion wet environments has become a critical focus research. However, most existing adhesive materials lack ability to transition rapidly reversibly between nonadhesive states, their is often limited single environment. In this study, smart interfacial hydrogel tunable properties across diverse liquid presented. By tailoring interchain interactions leveraging electrostatically induced traction hydrophilic hydrophobic chain segments, achieves reversible modulation response temperature changes while maintaining adhesion. Notably, its strength at elevated temperatures (45 °C) approximately three times greater than lower (5 °C). The exhibits an 227 kPa aqueous 213 oil‐containing environments. This innovative design strategy enables exhibit broad switchable, dynamic capabilities, unlocking significant potential for wide range applications.
Language: Английский
Citations
2
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 498, P. 155195 - 155195
Published: Aug. 27, 2024
Language: Английский
Citations
14
Advanced Science, Journal Year: 2024, Volume and Issue: 11(45)
Published: Oct. 11, 2024
Abstract Oral ulcers can be addressed using various biomaterials designed to deliver medications or cytokines. Nevertheless, the effectiveness of these substances is frequently limited in many patients due poor adherence, short retention time mouth, and less‐than‐optimal drug efficacy. In this study, a new hydrogel patch (FSH3) made silk fibroin/hyaluronic acid matrix with light‐sensitive adhesive qualities infused ferric iron/shikonin nanoparticles enhance healing effects presented. Initially, forms an barrier over mucosal lesions through straightforward local injection, solidifying when exposed UV light. Subsequently, FSH3 demonstrates superior reactive oxygen species elimination near‐infrared photothermal bactericidal activity. These characteristics support bacterial regulate oxidative levels, promoting wound's progression from inflammation tissue regeneration. diabetic rat model mimicking oral ulcers, significantly speeds up by adjusting inflammatory environment injured tissue, maintaining balance microbiota, faster re‐epithelialization. Overall, shows potential for rapid wound recovery may transform therapeutic methods managing diabetes.
Language: Английский
Citations
12
Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 34(46)
Published: June 28, 2024
Abstract Hydrogels hold great promise in the field of flexible electronics. Attempts this area tend to microstructure design hydrogels, giving them specific adhesion and multi‐sensing functions. Here, a novel phase separation‐derived anisotropic adhesive structural color hydrogel film is presented for visually The generated by template replicating colloidal crystal using separation emulsions hydrophilic monomer (acrylic acid, AA), hydrophobic (lauryl methacrylate, LMA), co‐monomer ([2‐(methacryloyloxy) ethyl] dimethyl‐(3‐sulfopropyl) ammonium hydroxide (SBMA)), surfactants (hexadecyl trimethyl bromide, CTAB) initiator (ammonium persulphate (APS)). appearance results asymmetric morphologies film, imparting with performance. Attributed formation inverse opal scaffold structure, featured vivid color, showing superior capability self‐reporting mechanical behavior. Additionally, benefitting from presence abundant ions, exhibits conductivity. Thus, resultant demonstrated stable dual‐signal sensing properties involving color‐changing conductivity feedback ability respond human activities. These features make proposed highly potential electronic field.
Language: Английский
Citations
10
Advanced Materials, Journal Year: 2024, Volume and Issue: 36(41)
Published: Aug. 12, 2024
Abstract Hydrogel electrode interfaces have shown tremendous promise in the acquisition of surface electromyography (EMG) signals. However, perspiration or moisture environments will trigger deadhesion between hydrogel electrodes and human skin. Despite hydrophobic/hydrophilic surfaces can perform anti‐moisture adhesion respectively, it remains a challenge to integrally form Janus with homogeneous mechanical elasticity electronic performance. Herein, induction strategy is proposed approach surfaces. The hydrophobic interaction surfactants molds regulates distribution monomers on surface. induce hydrophilic surface, while It presents new phenomenon reversal wettability inducing optional integral be easily obtained by molds. Balance adhesion, elasticity, conductivity endows patch durable conformal high‐fidelity EMG signals even sweaty epidermis due asymmetric This performs quantitative description muscle strength accurate fatigue assessment. offers reliable candidate for future practical applications continuous digital healthcare intelligent human–machine interaction, Metaverse.
Language: Английский
Citations
10
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159608 - 159608
Published: Jan. 1, 2025
Language: Английский
Citations
1
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159540 - 159540
Published: Jan. 1, 2025
Language: Английский
Citations
1
Composites Part B Engineering, Journal Year: 2024, Volume and Issue: 279, P. 111456 - 111456
Published: April 16, 2024
Language: Английский
Citations
8