Bioprinted Symbiotic Dressings: A Lichen‐Inspired Approach to Diabetic Wound Healing with Enhanced Bioactivity and Structural Integrity DOI
Hai Liu, Hongxiang Mei, Hejin Jiang

et al.

Small, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 11, 2024

Abstract Providing oxygen and preventing infection at wound sites are effective ways to heal diabetic chronic wounds. Inspired by natural lichens, a bioprinted biogenic hydrogel (BBH) containing microalgae probiotics is developed for therapeutics, which offers prolonged biogenetic supply inhibition probiotics. The rational design of symbiotic BBH with customizable structure microorganism composition enhances resilience against elevated glucose levels hypoxia, leading the increased migration ability fibroblasts angiogenic potential human umbilical vein endothelial cells. Notably, BBH‐treated wounds exhibit dense vascular distribution, reduced hypoxia inflammatory responses, enhanced epithelial differentiation keratinization abilities. Consequently, achieves rapid tissue repairing within 3 d restores approximately 90% whole skin 12 d. This work presents an engineered platform regulating biological microenvironment provides insights developing hybrid systems.

Language: Английский

Metal–phenolic network composites: from fundamentals to applications DOI Creative Commons
Zhixing Lin, Hai Liu, Joseph J. Richardson

et al.

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(22), P. 10800 - 10826

Published: Jan. 1, 2024

This review provides a guideline for the rational design of metal–phenolic network (MPN) composites—which are fabricated from MPN and one or more functional components ( e.g. , drugs, proteins)—for various applications across diverse disciplines.

Language: Английский

Citations

22

Bioinspired Nanochitin‐Based Porous Constructs for Light‐Driven Whole‐Cell Biotransformations DOI Open Access
Vishnu Arumughan, Hitesh Medipally, Arun Torris

et al.

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 3, 2025

Abstract Solid‐state photosynthetic cell factories (SSPCFs) are a new production concept that leverages the innate abilities of microbes to drive valuable chemicals. It addresses practical challenges such as high energy and water demand improper light distribution associated with suspension‐based culturing; however, these systems often face significant related mass transfer. The approach focuses on overcoming limitations by carefully engineering microstructure immobilization matrix through freeze‐induced assembly nanochitin building blocks. use nanochitins optimized size enabled formation macropores lamellar spatial organization, which significantly improves transmittance distribution, crucial for maximizing efficiency reactions. biomimetic crosslinking strategy, leveraging specific interactions between polyphosphate anions primary amine groups featured chitin fibers, produced mechanically robust wet‐resilient cryogels maintained their functionality under operational conditions. Various model biotransformation reactions leading value‐added chemicals performed in chitin‐based matrix. demonstrates superior or comparable performance existing state‐of‐the‐art matrices systems. findings suggest cryogel holds promise advancing development solid‐state factories, offering scalable solution improve productivity light‐driven biotransformation.

Language: Английский

Citations

2

Retrievable hydrogel networks with confined microalgae for efficient antibiotic degradation and enhanced stress tolerance DOI Creative Commons
Minwen Jiang, Jie Zheng, Yi Tang

et al.

Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)

Published: April 2, 2025

Language: Английский

Citations

2

Occurrence and health risk assessment of toxic metals and rare earth elements in microalgae: Insight into potential risk factors in new sustainable food resources DOI Creative Commons

Xiaopan Wu,

Xiaole Zhao,

Jiayong Hu

et al.

Food Chemistry X, Journal Year: 2024, Volume and Issue: 23, P. 101697 - 101697

Published: July 26, 2024

Microalgae are a promising sustainable food source with high nutritional value and environmental benefits. This study investigated the presence of toxic metals rare earth elements (REEs) in 68 microalgal-based products conducted probabilistic risk assessment to evaluate potential health risks. The findings revealed detection rates REEs (80.96% 100%) heavy (83.82% 100%), REE concentrations ranging from 0.0055 0.5207 mg/kg. Heavy were detected at following average concentrations: As (2.80 mg/kg) > Cr (1.27 Pb (0.30 Cd (0.20 Hg (0.01 mg/kg). Carcinogenic analysis for (3.004 × 10

Language: Английский

Citations

5

Unlocking 3D printing technology for microalgal production and application DOI Creative Commons

Han Sun,

Qian Gong,

Yuwei Fan

et al.

Advanced Biotechnology, Journal Year: 2024, Volume and Issue: 2(4)

Published: Oct. 8, 2024

Microalgae offer a promising alternative for sustainable nutritional supplements and functional food ingredients hold potential to meet the growing demand nutritious eco-friendly alternatives. With escalating impacts of global climate change increasing human activities, microalgal production must be enhanced by reducing freshwater land use minimizing carbon emissions. The advent 3D printing offers novel opportunities optimizing microalgae production, though it faces challenges such as high costs scalability concerns. This work aims provide comprehensive overview recent advancements in 3D-printed bioreactors focusing on techniques, bio-ink types, their applications across environmental, food, medical fields. review highlights benefits bioreactors, including improved mass transfer, optimized light exposure, biomass yield, augmented photosynthesis. Current future directions are also discussed new insights into boosting cultivation efficiency expanded applications.

Language: Английский

Citations

4

Harnessing photosynthesis for materials, devices, and environmental technologies DOI Creative Commons
Fan Jiang, Friedrich H. Kleiner,

Marie‐Eve Aubin‐Tam

et al.

Current Opinion in Biotechnology, Journal Year: 2025, Volume and Issue: 92, P. 103265 - 103265

Published: Feb. 6, 2025

Photosynthetic organisms convert solar light into chemical energy through the process of photosynthesis. The employment photosynthetic in novel materials and devices provides them with a solar-powered sustainable functionality. In general, photosynthesis utilizes light, water, CO2 to generate various organic compounds while releasing secondary valuable products such as O2, extracellular electrons, carbohydrates, or H2. light-dependent inputs outputs are harnessed for environmental purification, biomedical applications, production biofuel, electricity, nanomaterials, bioplastics. this review, we summarize photosynthesis-assisted engineering applications based on substrates processes, highlight key challenges that remain be addressed.

Language: Английский

Citations

0

Solving Challenges in Microalgae-Based Living Materials DOI Creative Commons
Friedrich H. Kleiner, Jeong‐Joo Oh,

Marie‐Eve Aubin‐Tam

et al.

ACS Synthetic Biology, Journal Year: 2025, Volume and Issue: 14(2), P. 307 - 315

Published: Feb. 21, 2025

Engineered living materials (ELMs) integrate aspects of material science and biology into a unique platform, leading to devices with features life. Among those, ELMs containing microalgae have received increased attention due the many benefits photosynthetic organisms provide. Due their relatively recent occurrence, still face challenges related reliability, lifetime, scalability, more, often based on complicated crosstalk cellular, material-based, environmental variables in time. This Viewpoint aims summarize potential avenues for improving ELMs, beginning an emphasis understanding cell's perspective stresses imposed them recurring flaws current ELMs. Potential solutions ease implementation will be discussed, ranging from choice organism, adjustments ELM design, various genetic modification tools, so as achieve longer lifetime improved functionality.

Language: Английский

Citations

0

Enhancing mixed-species microalgal biofilms for wastewater treatment: Design, construction, evaluation and optimisation DOI

Zhinan Liang,

Hang Zhong,

Quanyu Zhao

et al.

Bioresource Technology, Journal Year: 2025, Volume and Issue: 430, P. 132600 - 132600

Published: April 28, 2025

Language: Английский

Citations

0

Bioprinting of microalgae laden scaffold for tissue regeneration DOI Creative Commons

Davut Yerlikaya,

Benan İnan, Didem Özçimen

et al.

Journal of Applied Phycology, Journal Year: 2025, Volume and Issue: unknown

Published: May 2, 2025

Abstract In recent years, microalgae that can be a continuous source of oxygen for cells and rich in bioactive compounds, have been used as an innovative approach to prevent hypoxia after implantation biomaterials. Oxygen provided photosynthetically by the polar microalga ( Chlorella variabilis ) combination with human cells, even without external source. this study, 3D bioprinting laden scaffolds was investigated characterized before use wound healing. Prepared bioink consisted alginate different ratios collagen (5, 10 15%) C. cells. Printing carried out at mm s −1 pressure 50 kPa. Each sample had 0.6–0.7 mL volume 6–7 × 5 After process, were crosslinked 100 mM calcium chloride min incubated. It observed grew well over 6 days scaffold. Also, increase from 12 mg L determined. demonstrated that, development microalgae-laden is promising on delivery or compounds therapeutic agents.

Language: Английский

Citations

0

Evaluation of cultivation conditions in hydrogel systems to enhance Chlorella vulgaris growth DOI
Guangtao Yang, Mingyang Li, Jinglin Zhang

et al.

International Microbiology, Journal Year: 2025, Volume and Issue: unknown

Published: May 8, 2025

Language: Английский

Citations

0