Angewandte Chemie,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 27, 2024
Abstract
Propargylic
ethers
serve
as
useful
intermediates
for
the
synthesis
of
a
variety
complex
targets.
However,
propargylic
substitution
prefunctionalized
alkyne
starting
materials
remains
dominant
method
propargyl
ethers,
while
direct
etherification
simple
alkynes
via
C−H
functionalization
largely
underreported.
Herein,
we
report
an
organometallic
umpolung
approach
iron‐mediated
etherification.
A
telescopic
protocol
deprotonation
followed
by
mild
oxidative
coupling
with
alcohols
enabled
use
or
functionalized
expedient
excellent
functional
group
compatibility,
chemoselectivity
and
regioselectivity.
Russian Chemical Reviews,
Journal Year:
2024,
Volume and Issue:
93(7), P. RCR5125 - RCR5125
Published: July 1, 2024
The
chemistry
of
heterocyclic
compounds
has
traditionally
been
and
remains
a
bright
area
chemical
science
in
Russia.
This
is
due
to
the
fact
that
many
heterocycles
find
widest
application.
These
are
key
structural
fragments
most
drugs,
plant
protection
agents.
Many
natural
also
derivatives
heterocycles.
At
present,
more
than
half
hundreds
millions
known
collective
review
devoted
achievements
Russian
chemists
this
field
over
last
15–20
years.
presents
leading
heterocyclists
representing
both
RAS
institutes
university
science.
It
worth
noting
wide
scope
review,
terms
geography
author
teams,
covering
whole
our
large
country,
diversity
research
areas.
Practically
all
major
types
represented
review.
special
attention
focused
on
practical
applications
design
new
drugs
biologically
active
compounds,
high-energy
molecules,
materials
for
organic
electronics
photovoltaics,
ligands
coordination
chemistry,
other
rapidly
developing
advances
would
not
be
possible
without
development
fundamental
transformations
chemistry.<br>
Bibliography
—
2237
references.
Russian Chemical Reviews,
Journal Year:
2023,
Volume and Issue:
92(12), P. RCR5104 - RCR5104
Published: Dec. 1, 2023
After
the
appearance
of
green
chemistry
concept,
which
was
introduced
in
vocabulary
early
1990s,
its
main
statements
have
been
continuously
developed
and
modified.
Currently,
there
are
10–12
cornerstones
that
should
form
basis
for
an
ideal
chemical
process.
This
review
analyzes
accumulated
experience
achievements
towards
design
products
processes
reduce
or
eliminate
use
generation
hazardous
substances.
The
presents
views
leading
Russian
scientists
specializing
various
fields
this
subject,
including
homogeneous
heterogeneous
catalysis,
fine
basic
organic
synthesis,
electrochemistry,
polymer
chemistry,
based
on
bio-renewable
feedstocks
energetic
compounds
materials.
A
new
approach
to
quantitative
evaluation
environmental
friendliness
by
authors
is
described.
<br>
bibliography
includes
1761.
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(8), P. 2306 - 2312
Published: Jan. 1, 2024
Regioselective
electrochemical
C–H
sulfonylation–bromination
between
indolizines,
sodium
sulfinates,
and
KBr
has
been
established
in
an
undivided
cell,
which
serves
as
both
the
brominating
agent
electrolyte.
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
89(7), P. 4840 - 4850
Published: March 19, 2024
Here,
we
report
controlled
and
site-selective
C–H
alkenylation
dialkenylation
of
indolizines
pyrrolo[1,2-a]quinolines
with
β-alkoxyvinyl
trifluoromethylketones
under
simple
practical
conditions.
Moreover,
this
direct
strategy
can
also
be
extended
to
imidazo[1,2-a]pyridines.
Notably,
without
a
transition
metal
external
oxidant,
efficient
dehydrogenative
β-alkenylation
tertiary
amines
is
presented.
Beilstein Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
20, P. 2959 - 3006
Published: Nov. 18, 2024
Organic
peroxides
have
become
sought-after
functionalities,
particularly
following
the
multi-tone
consumption
in
polymer
production
and
success
medicinal
chemistry.
The
selective
introduction
of
a
peroxide
fragment
at
different
positions
on
target
molecule
is
priority
modern
reaction
design.
pioneering
Kharasch-Sosnovsky
peroxidation
became
basic
universal
platform
for
development
methods,
with
its
great
potential
rapid
generation
complexity
due
to
ability
couple
resulting
free
radicals
wide
range
partners.
This
review
discusses
recent
advances
radical
Kharasch-type
functionalization
organic
molecules
OOR
including
free-component
couplings.
discussion
has
been
structured
by
type
substrate
peroxidation:
C(sp
Journal of Heterocyclic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 20, 2024
ABSTRACT
A
straightforward
and
efficient
method
has
been
developed
to
access
a
variety
of
benzothiazole
derivatives
via
cascade
reductive
annulation.
Iodine
mediated,
one‐pot
three‐component
reaction
o
‐chloronitroarenes,
aryl
aldehydes,
elemental
sulfur
effectively
produce
benzothiazoles.
Moreover,
the
metal‐free
strategy
allows
facile
synthesis
diverse
2‐substituted
benzothiazoles
through
multiple
carbon–heteroatom
bonds
in
good
yields.
The
present
protocol
features
greener
approach,
readily
accessible
reagents,
broad
substrate
scope,
high
product
yields,
operational
simplicity.
ChemistrySelect,
Journal Year:
2024,
Volume and Issue:
9(36)
Published: Sept. 1, 2024
Abstract
β‐Ketosulfones
were
synthesized
from
enol
acetates
and
sodium
sulfinates
under
electrochemical
conditions.
The
starting
can
act
both
as
the
supporting
electrolyte
source
of
S‐centered
radicals,
allowing
electrolysis
to
proceed
without
external
salt.
Side
reactions
acetates’
oxidation
are
not
observed,
developed
process
is
quite
selective.
proposed
sulfonylation
compatible
with
a
wide
range
initial
sulfinates.
On
basis
literature
data,
control
experiments,
CV
studies,
presumable
reaction
pathway
suggested.
key
intermediates
sulfonyl
radical,
C‐centered
benzylic
β‐acetoxy‐β‐hydroxysulfone.
