Advanced Functional Materials,
Journal Year:
2021,
Volume and Issue:
31(42)
Published: July 23, 2021
Abstract
Excessive
and
unwarranted
administration
of
antibiotics
has
invigorated
the
evolution
multidrug‐resistant
microbes.
There
is,
therefore,
an
urgent
need
for
advanced
active
compounds.
Ionic
liquids
with
short‐lived
ion‐pair
structures
are
highly
tunable
have
diverse
applications.
Apart
from
their
unique
physicochemical
features,
newly
discovered
biological
activities
ionic
fascinated
biochemists,
microbiologists,
medical
scientists.
In
particular,
antimicrobial
properties
opened
new
vistas
in
overcoming
current
challenges
associated
combating
antibiotic‐resistant
pathogens.
Discussions
regarding
liquid
derivatives
monomeric
polymeric
forms
presented
here.
The
mechanism
parameters
that
affect
activities,
such
as
chain
length,
cation/anion
type,
cation
density,
polymerization,
considered.
potential
applications
biomedical
arena,
including
regenerative
medicine,
biosensing,
drug/biomolecule
delivery,
to
stimulate
scientific
community
further
improve
efficacy
liquids.
Advanced Science,
Journal Year:
2018,
Volume and Issue:
5(5)
Published: Feb. 22, 2018
Antibacterial
materials
are
recognized
as
important
biomaterials
due
to
their
effective
inhibition
of
bacterial
infections.
Hydrogels
3D
polymer
networks
crosslinked
by
either
physical
interactions
or
covalent
bonds.
Currently,
hydrogels
with
an
antibacterial
function
a
main
focus
in
biomedical
research.
Many
advanced
developed,
each
possessing
unique
qualities,
namely
high
water
swellability,
oxygen
permeability,
improved
biocompatibility,
ease
loading
and
releasing
drugs,
structural
diversity.
Here,
overview
the
structures,
performances,
mechanisms
action,
release
behaviors,
applications
various
hydrogel
formulations
is
provided.
Furthermore,
prospects
research
clinical
predicted.
Chemical Society Reviews,
Journal Year:
2020,
Volume and Issue:
49(11), P. 3605 - 3637
Published: Jan. 1, 2020
This
review
presents
the
recent
progress
of
mussel-inspired
hydrogels
from
fundamental
interaction
mechanisms
and
design
principles
to
promising
applications.
ACS Nano,
Journal Year:
2019,
Volume and Issue:
13(9), P. 10279 - 10293
Published: Sept. 4, 2019
Diabetic
wound
healing
and
angiogenesis
remain
a
worldwide
challenge
for
both
clinic
research.
The
use
of
adipose
stromal
cell
derived
exosomes
delivered
by
bioactive
dressing
provides
potential
strategy
repairing
diabetic
wounds
with
less
scar
formation
fast
healing.
In
this
study,
we
fabricated
an
injectable
adhesive
thermosensitive
multifunctional
polysaccharide-based
(FEP)
sustained
pH-responsive
exosome
release
promoting
FEP
possessed
properties
including
efficient
antibacterial
activity/multidrug-resistant
bacteria,
hemostatic
ability,
self-healing
behavior,
tissue-adhesive
good
UV-shielding
performance.
FEP@exosomes
(FEP@exo)
can
significantly
enhance
the
proliferation,
migration,
tube
endothelial
cells
in
vitro.
vivo
results
from
full-thickness
cutaneous
model
showed
that
FEP@exo
accelerated
stimulating
process
tissue.
enhanced
granulation
tissue
formation,
collagen
deposition,
remodeling,
re-epithelialization
probably
lead
to
skin
appendage
regeneration.
This
study
combining
molecules
into
should
have
great
achieving
satisfactory
other
vascular-impaired
related
wounds.
Chemical Society Reviews,
Journal Year:
2022,
Volume and Issue:
52(2), P. 473 - 509
Published: Dec. 9, 2022
Hydrogel-based
conductive
materials
for
smart
wearable
devices
have
attracted
increasing
attention
due
to
their
excellent
flexibility,
versatility,
and
outstanding
biocompatibility.
This
review
presents
the
recent
advances
in
multifunctional
hydrogels
electronic
devices.
First,
with
different
components
are
discussed,
including
pure
single
network
based
on
polymers,
additional
additives
(i.e.,
nanoparticles,
nanowires,
nanosheets),
double
additives.
Second,
a
variety
of
functionalities,
self-healing,
super
toughness,
self-growing,
adhesive,
anti-swelling,
antibacterial,
structural
color,
hydrophobic,
anti-freezing,
shape
memory
external
stimulus
responsiveness
introduced
detail.
Third,
applications
flexible
illustrated
strain
sensors,
supercapacitors,
touch
panels,
triboelectric
nanogenerator,
bioelectronic
devices,
robot).
Next,
current
challenges
facing
summarized.
Finally,
an
imaginative
but
reasonable
outlook
is
given,
which
aims
drive
further
development
future.
Advanced Functional Materials,
Journal Year:
2018,
Volume and Issue:
29(1)
Published: Nov. 13, 2018
Abstract
Antibacterial
hydrogel
has
received
extensive
attention
in
soft
tissue
repair,
especially
preventing
infections
those
associated
with
impaired
wound
healing.
However,
it
is
challenging
developing
an
inherent
antibacterial
integrating
excellent
cell
affinity
and
superior
mechanical
properties.
Inspired
by
the
mussel
adhesion
chemistry,
a
contact‐active
proposed
copolymerization
of
methacrylamide
dopamine
(MADA)
2‐(dimethylamino)ethyl
methacrylate
forming
interpenetrated
network
quaternized
chitosan.
The
reactive
catechol
groups
MADA
endow
contact
intensified
bactericidal
activity,
because
increases
exposure
bacterial
cells
to
positively
charged
strengthens
effect.
also
maintains
good
fibroblasts
hydrogel.
Moreover,
hybrid
chemical
physical
cross‐links
inner
makes
strong
tough
recoverability.
In
vitro
vivo
tests
demonstrate
that
this
promising
material
fulfill
dual
functions
promoting
regeneration
infection
for
wound‐healing
applications.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2020,
Volume and Issue:
8
Published: March 19, 2020
There
are
many
factors
involved
in
wound
healing,
and
the
healing
process
is
not
static.
The
therapeutic
effect
of
modern
dressings
clinical
management
wounds
documented.
However,
there
few
reports
regarding
reasonable
selection
for
certain
types
clinic.
In
this
article,
we
retrospect
history
dressing
development
classification
dressings.
addition,
pros
cons
mainstream
different
wounds,
such
as
diabetic
foot
ulcers,
pressure
burns
scalds,
chronic
leg
well
physiological
mechanisms
summarized.
This
article
provides
a
guideline
selecting
suitable
according
to
wounds.
ACS Nano,
Journal Year:
2022,
Volume and Issue:
16(2), P. 1708 - 1733
Published: Jan. 20, 2022
Wound
dressings
based
on
nanomaterials
play
a
crucial
role
in
wound
treatment
and
are
widely
used
whole
range
of
medical
settings,
from
minor
to
life-threatening
tissue
injuries.
This
article
presents
an
educational
review
the
accumulating
knowledge
this
multidisciplinary
area
lay
out
challenges
opportunities
that
lie
ahead
ignite
further
faster
development
clinically
valuable
technologies.
The
analyzes
functional
advantages
nanomaterial-based
gauzes
hydrogels
as
well
hybrid
structures
thereof.
On
basis,
state-of-the-art
advances
transfer
(semi)blind
approaches
evaluation
state
smart
enable
real-time
monitoring
diagnostic
functions
could
help
during
healing.
explores
translation
related
aspects
into
real-world
use.
ongoing
future
associated
with
clinical
decisions
presented
reviewed.
Asian Journal of Pharmaceutical Sciences,
Journal Year:
2022,
Volume and Issue:
17(3), P. 353 - 384
Published: Jan. 24, 2022
Bacterial
infection
and
the
ever-increasing
bacterial
resistance
have
imposed
severe
threat
to
human
health.
And
contamination
could
significantly
menace
wound
healing
process.
Considering
sophisticated
process,
novel
strategies
for
skin
tissue
engineering
are
focused
on
integration
of
bioactive
ingredients,
antibacterial
agents
included,
into
biomaterials
with
different
morphologies
improve
cell
behaviors
promote
healing.
However,
a
comprehensive
review
anti-bacterial
dressing
enhance
has
not
been
reported.
In
this
review,
various
as
dressings
will
be
discussed.
Different
kinds
agents,
including
antibiotics,
nanoparticles
(metal
metallic
oxides,
light-induced
agents),
cationic
organic
others,
their
recent
advances
summarized.
Biomaterial
selection
fabrication
structures
forms,
films,
hydrogel,
electrospun
nanofibers,
sponge,
foam
three-dimension
(3D)
printed
scaffold
regeneration,
elaborated
Current
challenges
future
perspectives
presented
in
multidisciplinary
field.
We
envision
that
provide
general
insight
elegant
design
further
refinement
dressing.
Advanced Functional Materials,
Journal Year:
2019,
Volume and Issue:
29(35)
Published: July 15, 2019
Abstract
A
growth
in
the
use
of
antibiotics
and
related
evolution
patients'
drug
resistance
calls
for
an
urgent
response
development
novel
curing
approaches
without
using
synthetic
antibiotics.
Here,
fabrication
a
low‐cost
cryogel
wound
dressing
applications
is
demonstrated.
The
composed
only
naturally
derived
components,
including
chitosan/silk
fibroin
as
scaffold
tannic
acid/ferric
ion
(TA/Fe
3+
)
stimuli‐responsive
agent
photothermal
therapy.
Based
on
multiple
weak
hydrogen
bonds
metal
ligand
coordination,
exhibits
good
flexibility
recoverability.
Its
highly
porous
structure
renders
to
be
strongly
hygroscopic
absorb
blood
hemostasis.
excellent
antibacterial
activity
both
Gram‐negative
positive
bacteria,
benefiting
from
high
transition
TA/Fe
complex.
Furthermore,
can
efficiently
promote
cell
proliferation
vitro.
Significantly,
animal
experiments
also
reveal
that
effectively
eradicate
microbes
at
accelerate
healing
process.
In
summary,
this
biorenewable
demonstrates
hemostatic
performance,
antimicrobial
activity,
accelerates
skin
regeneration,
which
has
great
application
potential
promising
material
clinical
use.
