The association between weekend warrior physical activity pattern and anxiety: evidence from a U.S. population-based study DOI Creative Commons
Zihao Chen, Xin Jian,

Junqiang Jia

et al.

BMC Psychiatry, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 25, 2025

This study investigates the association between Weekend Warrior (WW) pattern and risk of anxiety among American adults, offering insights into a more flexible exercise strategy for individuals with limited time regular during weekdays. We analyzed data from 2007–2012 National Health Nutrition Examination Survey (NHANES) to examine relationship different physical activity (PA) patterns anxiety. Multivariate logistic regression, subgroup interaction, restricted cubic spline analysis (RCS), sensitivity analyses were conducted assess this association. Compared inactive individuals, those engaging in WW (OR = 0.65, 95% CI: 0.48–0.90, p 0.010), insufficiently active 0.71, 0.62–0.82, < 0.001), or regularly 0.75, 0.65–0.87, 0.001) showed significantly lower Subgroup interaction revealed significant effect modification poverty income ratio (PIR) diabetes subgroups (P 0.05), while no interactions observed other variables. RCS nonlinear recreational moderate vigorous intensity 0.001). Sensitivity further confirmed stability findings. The was associated For unable consistently throughout week, offers practical alternative reducing anxiety, particularly levels diabetes.

Language: Английский

Neurological mechanism-based analysis of the role and characteristics of physical activity in the improvement of depressive symptoms DOI
Nan Wang, Shanshan Zhu, Shuyang Chen

et al.

Reviews in the Neurosciences, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 20, 2025

Abstract Depression is a common mental disorder characterized by high prevalence and significant adverse effects, making the searching for effective interventions an urgent priority. In recent years, physical activity (PA) has increasingly been recognized as standard adjunctive treatment disorders owing to its low cost, easy application, efficiency. Epidemiological data shows positive preventive therapeutic effects of PA on illnesses such depression. This article systematically describes prophylactic depression biological basis. A comprehensive literature analysis reveals that significantly improves depressive symptoms upregulating expression “exerkines” irisin, adiponectin, BDNF positively impacting neuropsychiatric conditions. particular, lactate could also play critical role in ameliorating due findings about protein lactylation novel post-transcriptional modification. The suggests terms brain structure, may improve hippocampal volume, basal ganglia (neostriatum, caudate-crustal nucleus) PFC density patients with MDD. summary, this study elucidates multifaceted potential mechanisms particular emphasis roles various exerkines. Future research further investigate different types, intensities, durations depression, well how better integrate into existing strategies achieve optimal outcomes health interventions.

Language: Английский

Citations

1
Wheel‐Running Exercise Alleviates Anxiety‐Like Behavior via Down‐Regulating S‐Nitrosylation of Gephyrin in the Basolateral Amygdala of Male Rats DOI Creative Commons

Ping‐Fen Yang,

Tai‐Lei Nie,

Xia‐Nan Sun

et al.

Advanced Science, Journal Year: 2024, Volume and Issue: unknown

Published: July 4, 2024

Physical exercise has beneficial effect on anxiety disorders, but the underlying molecular mechanism remains largely unknown. Here, it is demonstrated that physical can downregulate S-nitrosylation of gephyrin (SNO-gephyrin) in basolateral amygdala (BLA) to exert anxiolytic effects. It found level SNO-gephyrin significantly increased BLA high-anxiety rats and a downregulation at cysteines 212 284 produced effect. Mechanistically, inhibition by either Cys212 or Cys284 mutations surface expression GABA

Language: Английский

Citations

4
S-nitrosylation of peroxiredoxin 2 exacerbates hyperuricemia-induced renal injury through regulation of mitochondrial homeostasis DOI Creative Commons
Fei Han,

Ya Dong,

Qiaoyan Liu

et al.

Free Radical Biology and Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0
The association between weekend warrior physical activity pattern and anxiety: evidence from a U.S. population-based study DOI Creative Commons
Zihao Chen, Xin Jian,

Junqiang Jia

et al.

BMC Psychiatry, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 25, 2025

This study investigates the association between Weekend Warrior (WW) pattern and risk of anxiety among American adults, offering insights into a more flexible exercise strategy for individuals with limited time regular during weekdays. We analyzed data from 2007–2012 National Health Nutrition Examination Survey (NHANES) to examine relationship different physical activity (PA) patterns anxiety. Multivariate logistic regression, subgroup interaction, restricted cubic spline analysis (RCS), sensitivity analyses were conducted assess this association. Compared inactive individuals, those engaging in WW (OR = 0.65, 95% CI: 0.48–0.90, p 0.010), insufficiently active 0.71, 0.62–0.82, < 0.001), or regularly 0.75, 0.65–0.87, 0.001) showed significantly lower Subgroup interaction revealed significant effect modification poverty income ratio (PIR) diabetes subgroups (P 0.05), while no interactions observed other variables. RCS nonlinear recreational moderate vigorous intensity 0.001). Sensitivity further confirmed stability findings. The was associated For unable consistently throughout week, offers practical alternative reducing anxiety, particularly levels diabetes.

Language: Английский

Citations

0