Interface‐Engineered CuxO@Bi2MoO6 Heterojunctions to Inhibit Piezoelectric Screening Effect and Promote Double‐Nanozyme Catalysis for Antibacterial Treatment DOI
Guiyuan Zhang, Shan He,

Junwu Wei

et al.

Small, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 12, 2024

Sonodynamic therapy is confronted with the low acoustic efficiency of sonosensitizers, and nanozymes are accompanied by intrinsic catalytic activity. Herein, to increase piezopotential N-type piezoelectric semiconductors, P-N heterojunction designed inhibit screening effect (PSE) electron utilization enhance nanozyme P-type Cu

Language: Английский

Novel Spatially Asymmetric Copper Bismuthate‐Mediated Augmentation of Energy Conversion to Realize “Three‐Step” Tumor Suppression DOI Creative Commons
Jiarui Wang,

Haoqin Zheng,

Guangyao Hu

et al.

Advanced Science, Journal Year: 2024, Volume and Issue: 11(25)

Published: April 23, 2024

The generally undesirable bandgap and electron-hole complexation of inorganic sonosensitizers limit the efficiency reactive oxygen species (ROS) generation, affecting effectiveness sonodynamic therapy (SDT). Comparatively, novel polyvinylpyrrolidone-modified copper bismuthate (PCBO) are manufactured for a "three-step" SDT promotion. In brief, first, strong hybridization between Bi 6s O 2p orbitals in PCBO narrows (1.83 eV), facilitating rapid transfer charge carriers. Additionally, nonequivalent [CuO

Language: Английский

Citations

6
Emerging Piezoelectric Sonosensitizer for ROS-Driven Sonodynamic Cancer Therapy DOI Creative Commons
Guiyun Wang,

Yanxia Qi,

Zhuang Liu

et al.

Inorganics, Journal Year: 2025, Volume and Issue: 13(3), P. 71 - 71

Published: Feb. 26, 2025

As a non-invasive modality, sonodynamic therapy (SDT) offers several advantages in cancer treatment, including deep tissue penetration and precise spatiotemporal control, resulting from the interplay between low-intensity ultrasound sonosensitizers. Piezoelectric materials, known for their remarkable capacity of interconversion mechanical electrical energy, have garnered considerable attention biomedical applications, which can serve as pivotal sonosensitizers SDT. These materials generate internal electric fields via ultrasound-induced deformation, modulates alteration charge carriers, thereby initiating surface redox reactions to reactive oxygen species (ROS) realizing therapeutic efficacy This review provides an in-depth exploration piezoelectric utilized SDT, with particular emphasis on recent innovations, elucidation underlying mechanisms, optimization strategies advanced materials. Furthermore, incorporation immunotherapy, photodynamic, chemodynamic, chemotherapy is explored, emphasizing potential enhance outcomes. By examining basic principles effect its contributions this sheds light promising applications oncology. It also highlights future directions improving these expanding clinical utility tumor therapy.

Language: Английский

Citations

0
Pt–PtTe2 Nanoparticles with Heterojunction-Based Accelerated Electron Transfer for Efficient Tumor Therapy DOI

Haoqin Zheng,

Jun Chen, Jia Shi

et al.

ACS Applied Nano Materials, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Language: Английский

Citations

0
Sono-blasting Triggered Cascading-Amplification of Oxidative Stress for Enhanced Interventional Therapy of Hepatocellular Carcinoma DOI
Dong Li, Kexin Zhang, Kaiyang Wang

et al.

Nano Letters, Journal Year: 2024, Volume and Issue: 24(29), P. 8996 - 9003

Published: July 12, 2024

Interventional therapy is widely regarded as a highly promising treatment approach for nonsurgical liver cancer. However, the development of drug resistance and tolerance to hypoxic environments after embolization can lead increased angiogenesis, enhanced tumor cell stemness, greater invasiveness, resulting in metastasis recurrence. To address these challenges, novel involving use lecithin DSPE-PEG comodified Ca

Language: Английский

Citations

3
Ag-Doped SnSe Nanosheets for Enhanced NIR-II Light-Induced Apoptosis DOI
Dequan Xiao, Yan Gong, Jing Zhang

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 22, 2024

Triple-negative breast cancer (TNBC) is one of the most aggressive and challenging subtypes with limited treatment options poor prognosis. To overcome these obstacles, Ag-doped SnSe (ASS) nanosheets were used as photonic hyperthermia agents for treating TNBC. ASS featured a high photothermal-conversion efficiency photon effect. Additionally, biosafety assessments, including hemolysis assays histopathological analysis, confirmed that was biosafety. These findings suggest ASS, in synergy second near-infrared biowindow (NIR-II) light irradiation, offers noninvasive, effective, safe therapeutic strategy This innovative approach exemplifies evolving landscape TNBC treatment, where technology biology converge to offer more precise personalized therapies.

Language: Английский

Citations

1
Interface‐Engineered CuxO@Bi2MoO6 Heterojunctions to Inhibit Piezoelectric Screening Effect and Promote Double‐Nanozyme Catalysis for Antibacterial Treatment DOI
Guiyuan Zhang, Shan He,

Junwu Wei

et al.

Small, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 12, 2024

Sonodynamic therapy is confronted with the low acoustic efficiency of sonosensitizers, and nanozymes are accompanied by intrinsic catalytic activity. Herein, to increase piezopotential N-type piezoelectric semiconductors, P-N heterojunction designed inhibit screening effect (PSE) electron utilization enhance nanozyme P-type Cu

Language: Английский

Citations

0