Multi-hydroxyl POSS supported iridium complexes as a recyclable catalyst for selective synthesis of N-/C-substituted indoles and the total synthesis of HIV-1 fusion inhibitor

Journal of Catalysis, Journal Year: 2023, Volume and Issue: 429, P. 115205 - 115205

Published: Nov. 24, 2023

Language: Английский

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Pd(0)/TPPMS‐catalyzed Tsuji‐Trost type cross‐coupling of allylic alcohols with organoboron compounds in water

Asian Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 21, 2024

Abstract We demonstrated that the combination of a Pd(0) catalyst and water‐soluble TPPMS ligand has high activity for direct arylation readily available allylic alcohols in Tsuji–Trost type cross‐coupling. Various organoboron reagents can be applied, enabling rapid access to corresponding arylated products with wide range functional group tolerance. Kinetic studies revealed first‐order rate dependence alcohol, boronic acid, CsF Pd(0)/TPPMS concentrations. A Hammett study found slightly positive ρ value 0.79, suggesting partial negative charge is generated on aromatic ring aryl boronate rate‐determining transmetalation step. Based several control experiments, we concluded employing would proceed via oxo‐palladium mechanism.

Language: Английский

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Fabricating Effective and Recyclable Cadmium‐based Coordination Polymer for Selective Synthesis of 1,5‐Benzodiazepines

Asian Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 12(12)

Published: Oct. 9, 2023

Abstract Metal coordination polymers are widely applied in the synthesis of heterocyclic compounds due to advantages highly dispersed metal active sites, low cost and strong designability. Herein, employing 9‐benzyl‐3,6‐di( 1H ‐pyrazol‐1‐yl)‐ 9H ‐carbazole (BPC) as a ligand, cadmium‐coordinated polymer compound (Cd‐BPC) was facilely prepared by solvothermal method characterized energy dispersive spectrometer (EDS), flourier‐transform infrared spectroscopy (FT‐IR), scanning electron microscope (SEM), transmission microscopy (TEM) X‐ray photoelectron spectrometry (XPS). Employing Cd‐BPC catalyst, 1,5‐benzodiazepine derivatives were produced with relatively high yields through reaction o ‐phenylenediamine ketones, alcohols. Additionally, could be reused for at least 5 times without significant decrease.

Language: Английский

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Porous Cross-Linked Polymer PPBI@Mn Catalyzed the Selective Synthesis of Bisindolylmethane Derivatives

Catalysis Letters, Journal Year: 2024, Volume and Issue: 154(10), P. 5669 - 5682

Published: July 2, 2024

Language: Английский

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Recyclable Ni-Containing Coordination Polymer as an Efficient Catalyst for the Synthesis of Oxindole and Quinoline Derivatives through the Borrowing Hydrogen Strategy

Catalysts, Journal Year: 2023, Volume and Issue: 13(8), P. 1195 - 1195

Published: Aug. 9, 2023

A coordination polymer Ni-CIA has been designed, synthesized, and characterized via Fourier transform infrared spectroscopy (FT-IR), powder X-ray diffraction (XRD), scanning electron microscopy (SEM), photoelectron spectrometry (XPS), energy-dispersive (EDS), thermal gravimetric analysis (TGA). The resulting reveals a slice layer stacked combination structure good stability. Importantly, this exhibited high catalytic activity for the synthesis of oxindole quinoline derivatives borrowing hydrogen dehydrogenation reactions. Meanwhile, several control reactions were carried out to investigate possible mechanisms transformation. Finally, results recycling experiment indicate that could be recovered reused at least five times.

Language: Английский

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Six-membered ring systems: pyridines and benzo derivatives

Progress in heterocyclic chemistry, Journal Year: 2023, Volume and Issue: unknown, P. 383 - 425

Published: Jan. 1, 2023

Language: Английский

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Five-membered ring systems: with more than one N atom

Progress in heterocyclic chemistry, Journal Year: 2023, Volume and Issue: unknown, P. 281 - 332

Published: Jan. 1, 2023

Language: Английский

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