Neuroendocrine mechanisms involved in the physiological effects caused by skin-to-skin contact – With a particular focus on the oxytocinergic system

Infant Behavior and Development, Journal Year: 2020, Volume and Issue: 61, P. 101482 - 101482

Published: Sept. 9, 2020

Language: Английский

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Family integrated care: Supporting parents as primary caregivers in the neonatal intensive care unit

Pediatric Investigation, Journal Year: 2021, Volume and Issue: 5(2), P. 148 - 154

Published: June 1, 2021

ABSTRACT Family integrated care (FICare) is a collaborative model of neonatal which aims to address the negative impacts intensive unit (NICU) environment by involving parents as equal partners, minimizing separation, and supporting parent‐infant closeness. FICare incorporates psychological, educational, communication, environmental strategies support cope with NICU prepare them be able emotionally, cognitively, physically for their infant. has been associated improved infant feeding, growth, parent wellbeing self‐efficacy; important mediators long‐term neurodevelopmental behavioural outcomes. implementation requires multi‐disciplinary commitment, staff motivation, sufficient time preparation readiness change professionals relinquish power control instead develop partnerships parents. Successful culture have applied teams internationally, using practical approaches suited local environments. Strategies such meetings relational communication help break down barriers providing space co‐creation knowledge, negotiation caregiving roles development trusting relationships. The COVID‐19 pandemic highlighted vulnerability within programs parental presence in units profound separation. New technologies digital innovations can mitigate these challenges, renewed efforts embed philosophy practice during recovery beyond.

Language: Английский

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Parent–Infant Skin-to-Skin Contact and Stress Regulation: A Systematic Review of the Literature

International Journal of Environmental Research and Public Health, Journal Year: 2021, Volume and Issue: 18(9), P. 4695 - 4695

Published: April 28, 2021

Several studies have focused on neonatal maternal separation (MS) to investigate behavioural and neuroendocrine reactions lack of contact, but only a few early in the first days or weeks after birth. This literature review investigates vital importance contact touch by exploring how skin-to-skin (SSC) regulates stress mother-infant relationship. Various databases such as PubMed, Scopus, ScienceDirect were searched for published between 2015 2020. From 1141 articles, 22 declared eligible. The reviewed articles showed SSC child biological indicators autonomic nervous system (ANS), heart rate variability (HRV), cortisol, oxytocin. research concludes regulation, especially during COVID-19 pandemic. With no date indicating possible risk transmission following SSC, should continue be practiced all women, recommended WHO.

Language: Английский

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Systematic review confirmed the benefits of early skin‐to‐skin contact but highlighted lack of studies on very and extremely preterm infants

Acta Paediatrica, Journal Year: 2021, Volume and Issue: 110(8), P. 2310 - 2315

Published: May 11, 2021

We systematically reviewed the literature to identify benefits of early skin-to-skin contact (SSC) for all gestational ages.The MEDLINE, Embase and CINAHL databases were searched papers published in English from 1 January 1975 31 March 2020. Early SSC was defined as when infant placed directly onto mother's chest within 180 min birth. Two authors independently databases, appraised study quality extracted design outcome data. The primary outcomes infants' physiological stability after birth: thermoregulation stabilisation. secondary exclusive breastfeeding mother-infant interaction.We 30 studies that assessed SSC: 22 comprised term-born healthy infants eight focused on preterm or ill infants. These included various ages, birth methods cultural backgrounds. demonstrated stabilised neonatal parameters, promoted supported bonding. Most data term late births.This systematic review showed could be beneficial. Further focus providing very extremely with SSC, parental experiences, are needed enable adopted routine practice.

Language: Английский

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Supporting parents as essential care partners in neonatal units during the SARS‐CoV‐2 pandemic

Acta Paediatrica, Journal Year: 2021, Volume and Issue: 110(7), P. 2008 - 2022

Published: March 26, 2021

ABSTRACT Aim To review the evidence on safety of maintaining family integrated care practices and effects restricting parental participation in neonatal during SARS‐CoV‐2 pandemic. Methods MEDLINE, EMBASE, PsycINFO CINAHL databases were searched from inception to 14th October 2020. Records included if they reported scientific, empirical research (qualitative, quantitative or mixed methods) promoting for parents hospitalised neonates Two authors independently screened abstracts, appraised study quality extracted outcome data. Results We retrieved 803 publications assessed 75 full‐text articles. Seven studies included, reporting data 854 healthcare professionals, 442 parents, 364 26 other members, within 286 units globally. The pandemic response resulted significant changes unit policies parents' access care. Breastfeeding, bonding, caregiving, mental health staff stress negatively impacted. Conclusion This highlights that pandemic‐related hospital restrictions had adverse delivery outcomes neonates, families staff. Recommendations restoring essential are discussed.

Language: Английский

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Immediate skin‐to‐skin contact may have beneficial effects on the cardiorespiratory stabilisation in very preterm infants

Acta Paediatrica, Journal Year: 2022, Volume and Issue: 111(8), P. 1507 - 1514

Published: April 25, 2022

Abstract Aim Our aim was to investigate what effect immediate skin‐to‐skin contact with a parent had on the cardiorespiratory stabilisation of very preterm infants. Methods This randomised clinical trial conducted during 2018–2021 at two university hospitals three neonatal intensive care units in Norway and Sweden. Infants born from 28+0 32+6 weeks gestation were for first six postnatal hours or standard incubator care. The outcome composite stability score, based serial measures heart respiratory rate, support, fraction inspired oxygen saturation. Results We recruited 91 newborn infants mean gestational age 31+1 (range 28+4–32+6) birth weight 1534 555–2440) g: 46 received 45 group who an adjusted score 0.52 higher (95% confidence interval 0.38–0.67, p < 0.001) scale zero when compared control group. Conclusion Immediate beneficial effects

Language: Английский

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Resveratrol ameliorates maternal separation-induced anxiety- and depression-like behaviors and reduces Sirt1-NF-kB signaling-mediated neuroinflammation

Frontiers in Behavioral Neuroscience, Journal Year: 2023, Volume and Issue: 17

Published: May 18, 2023

Maternal separation in early life has a detrimental effect on the physiological and biochemical functions of brains offspring can lead to anxiety- depression-like behaviors later life. Resveratrol possesses variety pharmacological properties, including anti-inflammatory, anxiolytic, anti-depressive effects. In rodents, resveratrol attenuate induced by chronic unpredictable mild stress, estrogen deficiency, lipopolysaccharide. However, whether administration during adolescence counteract these when they result from maternal is unknown. this study, male C57BL/6J mice were separated their mothers for 4 h per day postnatal 2 (PND 2) PND 21; starting 61, was administered intraperitoneally at 40 mg/(kg/day –1 ) weeks. At 3 months age, anxiety assessed using series tasks consisting an open field test, elevated plus maze forced swimming tail suspension test. The hippocampal levels interleukin (IL)-1β, IL-6, tumor necrosis factor-alpha (TNF-α) measured ELISA, while those sirtuin 1 (Sirt1) nuclear factor kappa B (NF-κB) p65 determined western blotting PCR. results showed that led increased behaviors, enhanced pro-inflammatory cytokines, downregulated Sirt1/NF-κB signaling pathway offspring; however, effects could be reversed treatment with resveratrol. Our findings suggested ameliorate inflammation via activation pathway.

Language: Английский

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Parent psychological wellbeing in a single-family room versus an open bay neonatal intensive care unit

PLoS ONE, Journal Year: 2019, Volume and Issue: 14(11), P. e0224488 - e0224488

Published: Nov. 5, 2019

Background Studies of parents' psychological well-being in single-family rooms neonatal intensive care units have shown conflicting results. Aims To compare emotional distress the form depression, anxiety, stress and attachment scores among parents very preterm infants cared for a unit vs an open bay unit. Study design Prospective survey design. Subject Parents (132) 77 born at 28 0/7–32 0/7 weeks gestation two units. Outcome measures Duration parental presence was recorded. Scores depression (The Edinburgh Postnatal Depression Scale), anxiety State–Trait–Anxiety Inventory, Short Form Y), Parent Stressor Scale: questionnaire The Parenting Stress Index—short form) (Maternal Attachment Scale) measured 14 days after delivery, discharge, expected term date four months post-term. Results were present 21 hours/day room 7 Open Ninety-three percent fathers more than 12 hours per day during first week. Mothers had significantly lower score -1.9 (95% CI: -3.6, -0.1) points from birth to corrected age compared mothers unit, 14% 52% scored above cut-off point considered being high risk (p<0.005). Both reported levels hospitalization. There no differences between groups or discharge. Conclusion by hospitalization both supports that contribute wellbeing.

Language: Английский

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Association of a Zero-Separation Neonatal Care Model With Stress in Mothers of Preterm Infants

JAMA Network Open, Journal Year: 2022, Volume and Issue: 5(3), P. e224514 - e224514

Published: March 28, 2022

Importance

Active participation in care by parents and zero separation between their newborns is highly recommended during infant hospitalization the neonatal intensive unit (NICU).

Objective

To study association of a family integrated (FICare) model with maternal mental health at hospital discharge preterm newborn compared standard (SNC).

Design, Setting, Participants

This prospective, multicenter cohort included mothers infants born treated level-2 units Netherlands (1 single rooms [the FICare model] 2 control sites open bay units) May 2017 January 2020 as part AMICA (fAMily Integrated CAre ward). Participants admitted to participating units. Data analysis was performed from April 2021.

Exposures

complete couplet-care for mother-newborn dyad maternity and/or care.

Main Outcomes Measures

Maternal health, measured using Parental Stress Scale: NICU (PSS-NICU). Secondary outcomes survey scores on Hospital Anxiety Depression Scale, Postpartum Bonding Questionnaire, Perceived Parenting Self-efficacy satisfaction (using EMPATHIC-N). Parent CO-PARTNER tool) assessed potential mediator mediation analyses.

Results

A total 296 were included; 124 141 (87.9%) 115 155 (74.2%) SNC responded questionnaires (mean [SD] age: FICare, 33.3 [4.0] years; SNC, [4.1] years). Mothers had lower PSS-NICU stress (adjusted mean difference, −12.24; 95% CI, −18.44 −6.04) than specifically −1.273; −1.835 −0.712). present more (>8 hours per day: 105 125 [84.0%] vs 42 [36.5%]; adjusted odds ratio, 19.35; 8.13 46.08) participated score: 46.7 [6.9] 40.8 [6.7]; 5.618; 3.705 7.532). parent significant less depression anxiety indirect effect, −0.133; −0.226 −0.055), higher self-efficacy 1.855; 0.693 3.348), better bonding −0.169; −0.292 −0.068).

Conclusions Relevance

The our associated discharge; which improved outcomes. Future intervention strategies should aim reducing intensifying active

Trial Registration

Trial Register identifierNL6175

Language: Английский

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Early-life factors associated with neurobehavioral outcomes in preterm infants during NICU hospitalization

Pediatric Research, Journal Year: 2022, Volume and Issue: 92(6), P. 1695 - 1704

Published: March 25, 2022

Language: Английский

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