BMC Pediatrics, Journal Year: 2024, Volume and Issue: 24(1)
Published: Nov. 30, 2024
Language: Английский
Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(5), P. 1361 - 1361
Published: Feb. 27, 2024
Inflammatory bowel diseases (IBDs) have seen an exponential increase in incidence, particularly among pediatric patients. Psychological stress is a significant risk factor influencing the disease course. This review assesses interaction between and progression, focusing on articles that quantified inflammatory markers IBD patients exposed to varying degrees of psychological stress.
Language: Английский
Citations
8
Nursing Open, Journal Year: 2024, Volume and Issue: 11(1)
Published: Jan. 1, 2024
Abstract Aim To critically assess the effects of white noise on pain level, weight gain and vital signs (heart rate, respiratory rate oxygen saturation) preterm infants in neonatal intensive care units (NICUs). Design A systematic review meta‐analysis randomised controlled trials (RCTs). Methods Ten databases (PubMed, Cochrane Library, Embase, Web Science, CINAHL, PsycINFO, SinoMed, China National Knowledge Infrastructure, VIP Wanfang Data) were systematically reviewed from inception to July 2022. Two reviewers evaluated risk bias separately using Collaboration criteria extracted data a predesigned information form. Results The included eight eligible RCTs. According statistical analysis, significantly affected gain, heart saturation infants. Regardless outcome measurement timing, gestational age birth infants, subgroup analysis demonstrated that reduced promoted NICUs. Conclusion White is practical potentially useful therapy for premature neonates No Patient or Public Contribution.
Language: Английский
Citations
5
International Journal of Nursing Studies, Journal Year: 2024, Volume and Issue: 155, P. 104773 - 104773
Published: April 17, 2024
Exposure to repetitive pain during the neonatal period has been shown have important short and long-term effects on neurodevelopment of premature neonate can contribute experienced prolonged pain. A uniform taxonomy is still lacking this day which contributes suboptimal management in intensive care units. Accordingly, a scoping review exploring state knowledge about preterm neonates hospitalized unit will developing field provide recommendations for clinical management. To determine scope, extent, nature available literature Scoping review. An electronic search was conducted from inception November 2023 databases CINAHL, PubMed, Medline, Web Science, GeryLit.org Gray Source Index. Included studies discussed concepts related such as definitions pain, indicators contexts that result evaluation tools, consequences interventions Key were identified 86 included articles (n = 26), 39), 49), scales 56), 30) possible 22). While consensus definition yet be achieved, no proximate event cause time criterion by authors being relevant defining Interestingly, context hospitalization most indicative should guide its management, while only limited discussed. The findings foundation growing shed light ambiguity currently exists topic scientific literature. This summarizes key necessary better understanding stresses importance considering units, with objective improving developmental outcomes neonates. reveals are essential guiding
Language: Английский
Citations
5
Revista Eletrônica Acervo Saúde, Journal Year: 2025, Volume and Issue: 25, P. e17429 - e17429
Published: Jan. 11, 2025
Objetivo: Avaliar a associação entre consequências no desenvolvimento neuropsicomotor de acordo com o tempo permanência e procedimentos realizados em neonatos nas Unidades Terapia Intensiva Neonatal. Métodos: Trata-se uma revisão sistemática, tendo como público-alvo que foram admitidos Unidade Neonatal (UTIN). As buscas feitas 3 bases dados (BVS, Pubmed Cochrane Library) partir descritores: neonatos, UTIN neuropsicomotor. Os artigos encontrados filtrados pelo Software Rayyan avaliação da sua qualidade metodológica foi feita pela Newcastle-Ottawa Scale (NOS). Resultados: Foram identificados 8049 artigos, dos quais 23 considerados elegíveis para íntegra avaliação, sendo 11 desses incluídos na revisão. Verificou-se internados baixo peso ao nascer e/ou baixa idade gestacional, morbidades sujeitos cirúrgicos apresentaram maiores riscos comprometimento neurodesenvolvimento. Considerações finais: estudos demonstraram recém-nascidos períodos internação podem ter seu
Citations
0
Pain Management Nursing, Journal Year: 2025, Volume and Issue: unknown
Published: March 1, 2025
Language: Английский
Citations
0
Frontiers in Pediatrics, Journal Year: 2025, Volume and Issue: 13
Published: March 28, 2025
To identify sex-specific feeding patterns and associations with growth neurodevelopment in preterm infants during NICU through 2 years of corrected age (CA). A cohort study was conducted 216 (gestational 28 0/7 to 32 weeks). Daily regimens, including mother's own milk (MOM), human donor milk, formula; daily growth; acute chronic pain/stress were documented NICU. Network Neurobehavioral Scale (NNNS) (36 38 postmenstrual age), Bayley Scales Infant Toddler Development (Bayley) Edition III (1 CA) measured. Between week 9 16 after birth, only females showed a positive association between z-score proportion MOM intake before 8 (p < 0.05). Sex-differentiated stress observed positively correlated language or cognitive scores at CA = 0.01), this correlation not evident males. We discovered "window opportunity" for feeding, risk predictors up CA. These insights may inform development tailored potentially mitigating differences males females.
Language: Английский
Citations
0
Jornal de Pediatria, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Language: Английский
Citations
0
Microorganisms, Journal Year: 2023, Volume and Issue: 11(3), P. 814 - 814
Published: March 22, 2023
The objective of this study is to investigate the impact early life experiences and gut microbiota on neurobehavioral development in preterm infants during neonatal intensive care unit (NICU) hospitalization. Preterm were followed from NICU admission until their 28th postnatal day or discharge. Daily stool samples, painful/stressful experiences, feeding patterns, other clinical demographic data collected. Gut was profiled using 16S rRNA sequencing, operational taxonomic units (OTUs) selected predict neurobehaviors. assessed by Neonatal Neurobehavioral Scale (NNNS) at 36 38 weeks post-menstrual age (PMA). Fifty-five who had NNNS measurements included sparse log-contrast regression analysis. experienced a high level pain/stress hospitalization higher stress/abstinence scores. Eight identified be associated with subscales after controlling features, experiences. These OTUs taxa belonging seven genera, i.e., Enterobacteriaceae_unclassified, Escherichia-Shigella, Incertae_Sedis, Veillonella, Enterococcus, Clostridium_sensu_stricto_1, Streptococcus five Firmicutes two Proteobacteria phylum. enriched abundance Enterobacteriaceae_unclassified (OTU17) (OTU28) consistently less optimal outcomes. six also infant responses depending days stay. This explored dynamic specific for acute chronic NICU. pain/stressful dynamically
Language: Английский
Citations
9
Developmental Neuroscience, Journal Year: 2024, Volume and Issue: 46(5), P. 341 - 352
Published: Jan. 29, 2024
Introduction: Preterm infants experience tremendous early life pain/stress during their neonatal intensive care unit (NICU) hospitalization, which impacts neurodevelopmental outcomes. Mitochondrial function/dysfunction may interface between perinatal stress events and neurodevelopment. Nevertheless, the specific proteins or pathways linking mitochondrial functions to pain-induced outcomes in remain unidentified. Our study aims investigate associations among pain/stress, associated with function/dysfunction, neurobehavioral responses preterm infants. Methods: We conducted a prospective cohort study, enrolling 33 September 2017 July 2022 at two affiliated NICUs located Hartford Farmington, CT. NICU Network Neurobehavioral Scale (NNNS) datasets were evaluated explore potential association The daily experienced by infant’s stay was documented. At 36–38 weeks post-menstrual age (PMA), using NNNS buccal swabs collected for further analysis. Mass spectrometry-based proteomics on epithelial cells obtained from evaluate protein expression level. Lasso statistical methods abundance infants’ summary scores. Multiple linear regression Gene Ontology (GO) enrichment analyses performed examine how clinical characteristics be levels underlying molecular pathways. Results: During premature rupture of membrane (PPROM) negatively including leptin receptor binding activity, glutathione disulfide oxidoreductase activity response oxidative stress, lipid metabolism, phosphate proton transmembrane transporter outcomes; contrast, cytoskeletal regulation, barrier, protection function found optimal In addition, function-associated SPRR2A, PAIP1, S100A3, MT-CO2, PiC, GLRX, PHB2, BNIPL-2 demonstrated positive favorable outcomes, while ABLIM1, UNC45A, keratins, MUC1, CYB5B showed adverse Conclusion: function-related observed Large-scale studies longitudinal are warranted. Buccal could used predict
Language: Английский
Citations
3
Translational Pediatrics, Journal Year: 2024, Volume and Issue: 13(6), P. 946 - 962
Published: June 1, 2024
Sleep influences the interaction between infants and their environment, as well achievement of crucial milestones in motor language development. This is particularly significant for preterm vulnerable positions. However, prematurely born neonatal intensive care unit (NICU) are exposed to various stimuli such noise light, which disrupt normal sleep patterns. study assesses consolidates existing evidence on non-pharmacological strategies protecting promoting infants. By providing an evidence-based data repository, it offers a valuable reference clinical interventions.
Language: Английский
Citations
2