Visible-light-induced dehydrogenation of dihydroquinolinones via the combination of energy transfer and hydrogen atom transfers DOI
Feng Jin, Huayang Tang, Hao Guo

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 19, 2024

A visible-light-induced dehydrogenation of dihydroquinolinones was developed using photocatalyst thioxanthone (TX) and oxidant tert -butyl benzoperoxoate.

Language: Английский

A Highly Dispersed Heterogeneous Cobalt Catalyst for Efficient Domino Hydroformylation Reductive Amination of Olefins DOI Creative Commons
Kangkang Sun, Tianyue Su, Guoping Lu

et al.

Angewandte Chemie International Edition, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 29, 2025

Abstract The hydroaminomethylation of alkenes using CO and H 2 proceeds efficiently in the presence a heterogeneous Co−N/C catalyst with highly dispersed metal centers. Various secondary tertiary amines can be effectively synthesized from cyclic linear aliphatic this specific material. active sites optimal result synergistic effect atomically Co their surrounding N atoms, high surface area as well structural defects NC support. broad applicability (>54 examples), including pharmaceutically relevant molecules, together activity reusability, underline general catalytic system.

Language: Английский

Citations

0
A Highly Dispersed Heterogeneous Cobalt Catalyst for Efficient Domino Hydroformylation Reductive Amination of Olefins DOI Creative Commons
Kangkang Sun, Tianyue Su, Guoping Lu

et al.

Angewandte Chemie, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 29, 2025

Abstract The hydroaminomethylation of alkenes using CO and H 2 proceeds efficiently in the presence a heterogeneous Co−N/C catalyst with highly dispersed metal centers. Various secondary tertiary amines can be effectively synthesized from cyclic linear aliphatic this specific material. active sites optimal result synergistic effect atomically Co their surrounding N atoms, high surface area as well structural defects NC support. broad applicability (>54 examples), including pharmaceutically relevant molecules, together activity reusability, underline general catalytic system.

Language: Английский

Citations

0
Transition Metal‐Catalyzed Aminocarbonylation Reactions DOI
Fatemeh Doraghi, Mohammad Hossein Morshedsolouk,

Niki Raisi

et al.

The Chemical Record, Journal Year: 2025, Volume and Issue: unknown

Published: May 8, 2025

Abstract Transition‐metal‐catalyzed aminocarbonylation reactions using low‐cost and accessible CO gas as a C1 building block amine nucleophile have been widely used to prepare amides, which are broadly exist in bioactive drugs, natural products, polymers. This type of reaction has also applied construct various biologically active heterocycles. In this review, we highlight involving under transition metal catalysis systems (palladium, rhodium, ruthenium, iridium, iron, copper, cobalt) over the past decade.

Language: Английский

Citations

0
Synthesis and Photochemical Characterization of Indolizine Fluorophores Obtained by a Multicomponent Palladium Iodide−Catalyzed Oxidative Aminocarbonylation Approach DOI Creative Commons
Ida Ziccarelli, Roberta Amuso, Raffaella Mancuso

et al.

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(12)

Published: Jan. 19, 2024

Abstract A catalytic carbonylative method for the direct, multicomponent synthesis of indolizine fluorophores has been developed. The process is based on PdI 2 /KI‐catalyzed oxidative aminocarbonylation 2‐(pyridin‐2‐yl)pent‐4‐yn‐1‐carbonyl compounds leading to corresponding 2‐ynamide intermediates, followed in situ by 5‐ exo ‐ dig cyclization (by amine‐promoted conjugate addition pyridine ring nitrogen) and aromatization, give finally isolated N , ‐disubstituted 2‐(indolizin‐3‐yl)acetamides. Reactions are carried out under relatively mild conditions (100 °C 20 atm a 4 : 1 mixture CO−air 6–15 h) MeCN as solvent with low catalyst loading (0.33 mol% ), presence 0.5 equiv. KI 3 secondary amine. optical properties representative 2‐(indolizin‐3‐yl)acetamide products have also investigated.

Language: Английский

Citations

2
Low‐valent Tungsten Catalyzed Carbonylative Sonogashira Coupling Reactions of Aryl Iodides with Alkynes DOI
Chunsheng Li,

Yaoyang Chen,

Xin Huang

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(30)

Published: Aug. 7, 2024

Abstract A low‐valent tungsten catalyzed carbonylative Sonogashira coupling reactions has been established. The present protocol utilizes inexpensive and readily available W(CO) 6 as precatalyst proceeds in the presence of atmospheric CO, providing a practical method to series functionalized alkynones indoxyls compounds under mild reaction conditions. Moreover, simple system, good functional group tolerance broad substrate scope enable application this transformation synthesis carbonyl‐containing molecules.

Language: Английский

Citations

1
Direct Access to α,β‐Unsaturated γ‐Lactams via Palladium‐Catalysed Carbonylation of Propargylic Ureas DOI Creative Commons

Debora Schiroli,

Aleksandr Voronov, Francesco Pancrazzi

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 4, 2024

Abstract Additive carbonylations typically necessitate strong nucleophiles, such as alcohols or amines. In this study, we carbonylated a poorly nucleophilic urea, under oxidant‐free conditions. Our straightforward carbonylative strategy enables access to versatile α,β‐unsaturated γ‐lactams featuring an aminocarbonyl fragment, utilizing readily available propargylic ureas starting materials. The employment of the PdI 2 /KI catalytic system allowed complete regioselectivity ( 5‐endo‐dig ), high functional group tolerance, broad substrate scope well operational simplicity (oxidant‐free, organic ligand‐free and base‐free protocol). synthetic utility these is showcased through late‐stage functionalizations, Giese reactions peptide couplings.

Language: Английский

Citations

1
Synthesis of benzothienofuranones and dihydrobenzothienopyranones by palladium iodide-catalyzed carbonylative double cyclization DOI Creative Commons
Ida Ziccarelli, Raffaella Mancuso,

Domenico Santandrea

et al.

Journal of Catalysis, Journal Year: 2023, Volume and Issue: 427, P. 115101 - 115101

Published: Aug. 22, 2023

3-(2-(Methylthio)phenyl)prop-2-yn-1-ols have been successfully converted in one synthetic step into benzo[4,5]thieno[2,3-c]furan-1-ones by a PdI2/KI-catalyzed oxidative carbonylative double cyclization process, performed MeCN under relative mild conditions (1-10 mol % PdI2, 7 equiv of KI, 80 °C, 60 atm 4:1 mixture CO–air). The process takes place through an ordered sequence steps, involving 5-endo-dig S-cyclization, iodide-promoted demethylation the ensuing sulfonium salt, CO insertion, second (possibly, formation palladacycle intermediate followed reductive elimination), and Pd(0) reoxidation oxygen (from air) used as external benign oxidant. Under similar conditions, 4-(2-(methylthio)phenyl)but-3-yn-1-ols, bearing butynol moiety ortho to methylthio group, led dicarbonylation products, however, slightly tuning reaction dihydrobenzo[4,5]thieno[3,2-c]pyran-1-ones could be selectively obtained with no dicarbonylated byproduct. structures four representative including two tetracyclic derivatives, confirmed XRD analysis.

Language: Английский

Citations

3
Enhanced Hydrazine Electrooxidation Activities on Novel Benzofused Tricyclic Heterocyclic Derivatives DOI Creative Commons

Omrüye Ozok Arıcı,

Raffaella Mancuso, Bartolo Gabriele

et al.

ACS Omega, Journal Year: 2024, Volume and Issue: 9(39), P. 40644 - 40649

Published: Sept. 17, 2024

In this study, some benzofused tricyclic heterocyclic derivatives have been tested as possible new catalysts for anode hydrazine electrooxidation in a direct fuel cell (DHFC). Electrochemical studies were carried out solution media containing 1 M KOH and + 0.5 N

Language: Английский

Citations

0
Palladium Iodide Catalyzed Oxidative Carbonylations DOI Creative Commons
Bartolo Gabriele

Tetrahedron Chem, Journal Year: 2024, Volume and Issue: 12, P. 100107 - 100107

Published: Nov. 1, 2024

Language: Английский

Citations

0
Visible-light-induced dehydrogenation of dihydroquinolinones via the combination of energy transfer and hydrogen atom transfers DOI
Feng Jin, Huayang Tang, Hao Guo

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 19, 2024

A visible-light-induced dehydrogenation of dihydroquinolinones was developed using photocatalyst thioxanthone (TX) and oxidant tert -butyl benzoperoxoate.

Language: Английский

Citations

0