Unmet supportive care needs of breast cancer survivors: a systematic scoping review

BMC Cancer, Journal Year: 2023, Volume and Issue: 23(1)

Published: June 26, 2023

Abstract Background Breast cancer is the most common type of in women worldwide. Though improved treatments and prolonged overall survival, breast survivors (BCSs) persistently suffer from various unmet supportive care needs (USCNs) throughout disease. This scoping review aims to synthesize current literature regarding USCNs among BCSs. Methods study followed a framework. Articles were retrieved Cochrane Library, PubMed, Embase, Web Science, Medline inception through June 2023, as well reference lists relevant literature. Peer-reviewed journal articles included if BCSs reported. Inclusion/exclusion criteria adopted screen articles’ titles abstracts entirely assess any potentially pertinent records by two independent researchers. Methodological quality was independently appraised following Joanna Briggs Institute (JBI) critical appraisal tools. Content analytic approach meta-analysis performed for qualitative quantitative studies respectively. Results reported according PRISMA extension reviews. A total 10,574 77 finally. The risk bias low moderate. self-made questionnaire used instrument, Short-form Supportive Care Needs Survey (SCNS-SF34). 16 domains finally identified. Social support (74%), daily activity (54%), sexual/intimacy (52%), fear recurrence/ spreading (50%), information (45%) top needs. Information psychological/emotional appeared frequently. found be significantly associated with demographic factors, disease psychological factors. Conclusion are experiencing large number fearing recurrence, activity, sexual/intimacy, psychology information, proportions ranging 45% 74%. Substantial heterogeneity populations assessment tools observed. There need further research identify standard evaluation tool targeted on Effective interventions based guidelines should formulated conducted decrease future.

Language: Английский

---

Are breast cancer patients with low distress at diagnosis at risk of psychological symptoms later in their disease trajectory? Considerations for when to screen for distress

Acta Oncologica, Journal Year: 2025, Volume and Issue: 64, P. 105 - 113

Published: Jan. 25, 2025

To target psychological support to cancer patients most in need of support, screening for distress has been advocated and, some settings, also implemented. Still, no prior studies have examined the appropriate 'dosage' and whether before treatment may be sufficient or if further screenings during are necessary. We development symptom trajectories breast with low surgery explored potential risk factors developing burdensome symptoms at a later point time. In total, 299 newly diagnosed who scored < 7 on thermometer were included between August 2017 October 2019 Department Breast Surgery, Rigshospitalet, Copenhagen. Patients followed through electronic questionnaires baseline after 6, 12, 18 months. used latent class mixed models identify sub-groups similar distress, anxiety, depression, cancer-specific health-related quality life, self-efficacy, fear recurrence over Logistic multinomial regression analyses applied examine clinical sociodemographic associated specific trajectories. did not any women diagnosis developed disabling up months diagnosis. However, we sub-group 52% experienced persistent mild anxiety (Generalised Anxiety Disorder [GAD]-7 score 5-9). Adjusted modalities characteristics, having social (odds ratio [OR]: 2.90; 95% confidence interval [CI]: 1.07-7.87) living partner (OR: 3.18; CI: 1.38-7.34) more likely experience anxiety. The results show that majority do an increase Screening essential step professional symptoms.

Language: Английский

---

Cognitive impairment following breast cancer treatments: an umbrella review

The Oncologist, Journal Year: 2024, Volume and Issue: 29(7), P. e848 - e863

Published: May 9, 2024

Cancer-related cognitive impairment (CRCI) refers to a decline associated with cancer or its treatments. While research into CRCI is expanding, evidence remains scattered due differences in study designs, methodologies, and definitions. The present umbrella review aims provide comprehensive overview of the current regarding impact different breast therapies on functioning, particular focus interplay among objective deficits (ie, measured standardized tests), subjective concerns, self-reported), other mediating psycho-physical factors.

Language: Английский

---

Investigating fear of cancer recurrence among female breast cancer survivors and their spouses in southwest China: a cross-sectional study

BMJ Open, Journal Year: 2024, Volume and Issue: 14(2), P. e077964 - e077964

Published: Feb. 1, 2024

Objectives Examining fear of cancer recurrence (FCR) among breast survivors and their spouses, the protective effect family resilience on FCR couples affected by cancer. Design Cross-sectional survey design. Setting Ten general grade IIIa (>500 beds) hospitals in southwest China. Participants Overall, 392 early spousal caregivers (N=392) were recruited from centres hospitals. Primary secondary outcome measures Spouses’ survivors’ primary measures. Family perceived stress Using a convenience sampling method, we collected data on-site using paper questionnaires. The Chinese version Resilience Assessment Scale, Perceived Stress Fear Progression Questionnaire Short Form Questionnaire-Short for spouses used to evaluate outcomes. Results model accounted 66.3% 53.6% variance spouses’ FCR, respectively. directly negatively (β=−0.22; β=−0.13; β=−0.19). was partial mediator association between (β=−0.070; 95% CI :−0.151 –0.022). partially mediated (β=−0.048; CI= −0.092 –0.015). played significant chain-mediated role (β=−0.061; CI: −0.119 Conclusions Family-centred approaches reducing can improve psychological well-being ultimately reduce FCR. Medical staff should consider feelings when devising intervention plan, which address families’ potential mobilise community resources increasing resilience.

Language: Английский

---

The trajectories of psychosocial adjustment among young to middle-aged women with breast cancer: A prospective longitudinal study

European Journal of Oncology Nursing, Journal Year: 2024, Volume and Issue: 71, P. 102617 - 102617

Published: May 22, 2024

Language: Английский

---

Social Support and Fear of Cancer Recurrence Among Chinese Breast Cancer Survivors: The Mediation Role of Illness Uncertainty

Frontiers in Psychology, Journal Year: 2022, Volume and Issue: 13

Published: March 16, 2022

To examine the relations between social support, illness uncertainty (IU), and fear of cancer recurrence (FCR).Using data from a convenience sample 231 breast survivors in China to perform structural equation modeling with bootstrapping estimation. Participants were recruited general hospital Shenyang, China. completed Perceived Social Support Scale, Mishel Uncertainty Illness Fear Cancer Recurrence Inventory- Shorter Form.The majority have FCR (67.5%). was significantly negatively associated positively IU (both P < 0.01). Moreover, found mediate relationship support (standardized indirect effect = -0.18; bias-corrected 95% confidence interval: -0.255, -0.123).The findings final model. Good can directly mitigate FCR, while play mediation role FCR. Further studies should be conducted explore effective interventions for ultimately survivors.

Language: Английский

---

Recent advancement in breast cancer treatment using CAR T cell therapy:- A review

Advances in Cancer Biology - Metastasis, Journal Year: 2023, Volume and Issue: 7, P. 100090 - 100090

Published: Feb. 6, 2023

Breast Cancer arises to be the most diagnosed cancer type in recent decades. It ranks vulnerable among women terms of incidence and mortality. In 2020, 2.3 million were with breast cancer, 6.85 lacs death reported globally. Here, we will focus mainly on TNBC, complicated subtype. Therefore, novel treatment modalities are urgently required. Treatments like chemotherapy radiotherapy limit efficacy therapeutic outcomes. Thus, new specific ideas coming up find a way out. For triple-negative (TNBC), which is currently complex challenging subtype treat, still standard care. There has been lot study into treatments for people TNBC because its poor prognosis high chance clinical recurrence. Chimeric antigen receptor (CAR) T cell-based immunotherapy directs patient's immune system recognize eradicate tumor cells that express tumor-associated antigens (TAAs). opens area research. Antigen Receptor (CAR-T) cell therapy an derived from adoptive relocation. CAR-T well equipped antibodies identify self-tumor cells, thus bringing out cytotoxic CARs modified receptors improved specificity responsiveness intensify recognition cells. The effects treatment, including have not lived expectations solid tumors despite triumphs treating hematologic malignancies. this review, discuss some developments field cancer-specific using CAR-T.

Language: Английский

---

Psychological distress in adult women of reproductive age at different stages after breast cancer diagnosis: A qualitative study

Journal of Clinical Nursing, Journal Year: 2024, Volume and Issue: 33(5), P. 1921 - 1932

Published: Jan. 29, 2024

Abstract Aim To explore the actual experience of psychological distress adult women reproductive age at different stages after breast cancer diagnosis. Design Qualitative. Methods Eighty‐one patients with cancer‐related thermometer scores >4 were selected using a purposive sampling method. Patients divided into newly diagnosed and 1‐, 3‐, 6‐, 9‐ 12‐month groups according to time since diagnosis then interviewed. A phenomenological approach was adopted analyse interview content, themes extracted. Results Women exhibited levels depending on diagnosis, showing highest distress. Within 1 year post‐diagnosis, events caused Themes extracted new 12 months post‐diagnosis included sadness disbelief, loss control, optimistic but concerned, physical mental exhaustion, difficulties returning society limited sexual intimacy, respectively; all expressed concerns. Conclusion Clinical nurses should focus psychologically distressing provide targeted interventions distinct phases. For childbearing age, clinical pay particular attention patients' marriage Implications for Profession and/or Patient Care During that cause differ Nurses core stressful perform specific nursing interventions. Impact holistic care, consider emotional changes may undergo. fertility concerns, be able evidence‐based professional guidance preservation techniques. Reporting Method The study reported consolidated criteria reporting qualitative research guidelines. or Public Contribution contributed data collection through interviews.

Language: Английский

---

Fear of Recurrence in Young Adult Cancer Patients—A Network Analysis

Cancers, Journal Year: 2022, Volume and Issue: 14(9), P. 2092 - 2092

Published: April 22, 2022

Due to the high survival rates of many young cancer patients and a risk second tumors, fear recurrence (FCR) can cause serious impairment for adolescent adult (AYA) patients. The aim this study is analyze structure Fear Disease Progression Questionnaire (FoP-Q-12) better understand construct FCR. We performed cross-sectional survey on sample AYA aged 15-39 years with different tumor entities. FCR was measured using FoP-Q-12, network analysis conducted examine relationship symptoms. importance individual items in determined centrality analyses. A total 247 (81.8% female, median age 31.0 years) participated study. mean score 35.9 (SD = 9.9). majority reported having (59.5%), according established cut-off. two questionnaire strongest association related fears about work, most central symptom medical interventions. emotional issues indicates that these symptoms should be prioritized development interventions targeting Further research address topic larger samples other groups longitudinal studies.

Language: Английский

---

Exploring fear of cancer recurrence and related factors among breast cancer patients: A cross‐sectional study

Journal of Advanced Nursing, Journal Year: 2023, Volume and Issue: 80(6), P. 2403 - 2414

Published: Dec. 2, 2023

Abstract Aims Fear of cancer recurrence (FCR) is a multifaceted concept influenced by individual characteristics, social support, psychological factors. This study aims to identify distinct FCR profiles among breast patients and explore the associated variables with these patterns. Design A cross‐sectional was conducted from April 2022 March 2023. Methods convenience sample 339 completed questionnaire that assessed general disease‐related data, including Progression Questionnaire‐Short Form, Social Support Rating Scale, Medical Coping Modes Questionnaire. Statistical analysis involved latent profile (LPA) multinomial logistic regression. Results Three patterns were found: low fear (28.9%), moderate (51.3%), high (18.0%). The identified family monthly income, employment status, utilization confrontation coping mode avoidance mode, as factors impacted FCR. Conclusions medical modes have been found impact newly diagnosed patients. Healthcare professionals should focus on addressing at diagnosis implement effective interventions, such promoting support encouraging adaptive coping, alleviate this concern. Impact Urgently in Chinese imperative due its profound influence their holistic health. Through advanced LPA, we categorized progression, highlighting risks. These findings implications for healthcare strategies, offering new insights manage improve patient well‐being. Our adds fresh perspective underlying patients, contributing broader comprehension management complex survivorship issue. Patient or Public Contribution No public contribution.

Language: Английский

---