Legal and Criminological Psychology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 28, 2025
Abstract
Dissociative
amnesia
or
psychogenic
are
established
diseases
in
psychiatry,
but
their
existence
and
aetiology
sometimes
questioned
by
researchers
working
primarily
experimental
fields
of
psychology.
The
validity
the
diagnoses
is
defended
(a)
pointing
to
for
centuries
existing
tradition
disease
conditions,
(b)
likely
context
(repeated)
situations
learned
helplessness,
stress,
trauma,
(c)
a
downregulation
emotional
reactivity.
defined
as
memory
blockade,
usually
induced
an
adverse
environment
which
appropriate
coping
strategies
lacking.
influence
lack
psychic
wellbeing
on
brain
worked
out
results
from
structural
functional
imaging
using
examples
Takotsubo‐cardiomyopathy
transient
global
amnesia.
Concomitant
psychiatric
conditions
specific
personality
traits
patients
with
dissociative
discussed.
It
concluded
that
valid
concept
distinct
neural
correlates
withstands
criticisms
few
psychologists.
Biological Psychiatry Global Open Science,
Journal Year:
2021,
Volume and Issue:
1(4), P. 272 - 282
Published: June 12, 2021
Adolescence
is
a
period
of
increased
vulnerability
for
internalizing
problems,
particularly
following
stressful
life
events.
We
examined
how
emotion
regulation
and
brain
structure
function
were
associated
with
problems
during
the
COVID-19
pandemic
moderated
association
between
pandemic-related
stressors
problems.Data
are
from
longitudinal
sample
(N
=
145,
age
range,
10-15
years)
strategically
assessed
at
3
crucial
time
points:
before
pandemic,
early
stay-at-home
order
period,
again
6
months
later.
associations
amygdala
hippocampal
volume
activation
an
emotional
processing
task
use
strategies
problems.Greater
exposure
to
was
higher
both
later
in
pandemic.
Youths
who
reported
more
frequent
rumination
expressive
suppression
lower
cognitive
reappraisal
had
Higher
left
neutral
relative
fearful
faces
greater
stronger
link
pandemic.Stressors
related
strongly
adolescent
as
individual
differences
reactivity
their
underlying
neural
mechanisms.
Interventions
that
reduce
foster
adaptive
skills
may
protect
against
psychopathology
this
heightened
stress.
Frontiers in Human Neuroscience,
Journal Year:
2021,
Volume and Issue:
15
Published: June 1, 2021
Early
life
adversity
(ELA),
such
as
child
maltreatment
or
poverty,
engenders
problems
with
emotional
and
behavioral
regulation.
In
the
quest
to
understand
neurobiological
sequelae
mechanisms
of
risk,
amygdala
has
been
major
focus.
While
basic
functions
this
region
make
it
a
strong
candidate
for
understanding
multiple
mental
health
issues
common
after
ELA,
extant
literature
is
marked
by
profound
inconsistencies,
reports
larger,
smaller,
no
differences
in
regional
volumes
area.
We
believe
integrative
models
stress
neurodevelopment,
grounded
“
allostatic
load
,”
will
help
resolve
inconsistencies
impact
ELA
on
amygdala.
review,
we
attempt
connect
past
research
studies
new
findings
animal
cellular
neurotransmitter
mediators
buffering
extreme
fear
generalization
onto
testable
clinical
concepts.
Drawing
greater
inescapability
over
unpredictability
models,
propose
mechanism
which
aggravates
an
exhaustive
cycle
expansion
subsequent
toxic-metabolic
damage.
sequela
psychosocial
mal/adaptation
bridging
attachment,
emotion
processing,
social
functioning.
Lastly,
conclude
review
proposing
multitude
future
directions
preclinical
work
humans
that
suffered
ELA.
Frontiers in Psychiatry,
Journal Year:
2024,
Volume and Issue:
15
Published: March 4, 2024
Objectives
Major
Depressive
Disorder
(MDD)
is
significantly
influenced
by
childhood
trauma
(CT),
affecting
brain
anatomy
and
functionality.
Despite
the
unique
disease
trajectory
in
MDD
patients
with
CT,
underlying
neurobiological
mechanisms
remain
unclear.
Our
objective
to
investigate
CT’s
impact
on
white
matter
structure
of
MDD.
Methods
This
research
employed
tract-based
spatial
statistics
(TBSS)
detect
variations
between
groups
Fractional
Anisotropy
(FA)
throughout
whole
71
medication-free
97
HCs.
Participants
filled
out
Childhood
Trauma
Questionnaire
(CTQ)
assessments
for
depression
anxiety
symptoms.
The
relationship
FA
CTQ
scores
was
explored
partial
correlation
analysis,
adjusting
factors
such
as
age,
gender,
educational
background,
length
illness.
Results
Compared
HCs,
group
showed
decreased
values
right
posterior
limb
internal
capsule
(PLIC),
inferior
fronto-occipital
fasciculus
(IFOF),
bilateral
superior
longitudinal
(SLF).
Simple
effects
analysis
revealed
that
compared
HC-CT,
MDD-CT
demonstrated
PLIC,
IFOF,
SLF.
MDD-nCT
PLIC
IFOF
HC-nCT.
total
subscale
were
negatively
correlated
Conclusion
SLF
may
potentially
be
CT
during
development
individuals
These
results
enhance
our
knowledge
role
pathophysiology
which
influences
PLoS ONE,
Journal Year:
2025,
Volume and Issue:
20(1), P. e0317573 - e0317573
Published: Jan. 16, 2025
Post-traumatic
Stress
Disorder
(PTSD),
Major
Depressive
(MDD),
and
Adjustment
(AdjD)
are
highly
prevalent
among
military
personnel,
often
presenting
diagnostic
challenges
due
to
overlapping
symptoms
reliance
on
self-reporting.
The
amygdala,
particularly
the
basolateral
complex
involved
in
fear-related
memory
formation
extinction
recall,
plays
a
crucial
role
emotional
processing.
Abnormalities
these
amygdala
nuclei
implicated
PTSD
may
distinguish
it
from
other
disorders
like
MDD
AdjD,
where
mechanisms
less
central.
Investigating
structural
differences
specific
could
enhance
precision
inform
targeted
interventions.
This
study
aimed
explore
volumetric
patients
with
PTSD,
MDD,
comorbid
(PTSD+MDD),
AdjD
using
routine
clinical
MRI
data.
We
hypothesized
that
would
exhibit
distinct
volumes
compared
those
or
AdjD.
Additionally,
we
examined
influence
of
symptom
duration,
prior
medication,
psychotherapeutic
experience
volumes.
conducted
retrospective
cross-sectional
185
personnel
(162
men,
23
women)
diagnosed
(n
=
50),
70),
PTSD+MDD
38),
27).
High-resolution
T1-weighted
scans
were
obtained
3T
Siemens
Skyra
scanner.
Amygdala
subfields
automatically
segmented
volumetrized
FreeSurfer
software.
Analysis
covariance
(ANCOVA)
models
across
groups,
controlling
for
estimated
total
intracranial
volume
(eTIV),
age,
gender.
Exploratory
analyses
included
medication
use,
psychotherapy
as
additional
covariates.
Sensitivity
further
impact
depressive
episode
type
(first
vs.
recurrent),
severity
(mild,
moderate,
severe),
duration.
main
revealed
no
significant
medial
PTSD+MDD,
groups.
did
not
identify
associations
between
psychotherapy.
also
showed
related
type,
severity,
Our
findings
suggest
that,
within
this
population,
measured
data
do
significantly
differ
indicates
volumetry
alone
suffice
stress-related
settings.
highlights
complexity
diagnosing
mental
health
conditions
underscores
need
comprehensive
approaches
integrate
neuroimaging
assessments.
Future
research
should
include
healthy
control
consider
brain
regions
functional
connectivity,
employ
longitudinal
designs
better
understand
temporal
dynamics
changes
their
relation
symptomatology.
