Health benefits, mechanisms of interaction with food components, and delivery of tea polyphenols: a review

Critical Reviews in Food Science and Nutrition, Journal Year: 2023, Volume and Issue: 64(33), P. 12487 - 12499

Published: Sept. 4, 2023

Tea polyphenols (TPs) are the most important active component of tea and have become a research focus among natural products, thanks to their antioxidant, lipid-lowering, liver-protecting, anti-tumor, other biological activities. Polyphenols can interact with food components, such as protein, polysaccharides, lipids, metal ions further improve texture, flavor, sensory quality food, widely used in fields, preservatives, antibacterial agents packaging. However, instability TPs under conditions light or heat low bioavailability gastrointestinal environment also hinder application food. In this review, we summarized health benefits TPs. order better use analyzed form mechanism interaction between main polysaccharides proteins. Moreover, reviewed into optimizing applications by bio-based delivery systems, liposomes, nanoemulsions, nanoparticles, so stability bioactivity application. As an effective ingredient, great potential be applied functional produce for human health.

Language: Английский

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Sleep Deprivation and Gut Microbiota Dysbiosis: Current Understandings and Implications

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(11), P. 9603 - 9603

Published: May 31, 2023

Gut microbiota comprises the microbial communities inhabiting our gastrointestinal (GI) tracts. Accordingly, these complex play a fundamental role in many host processes and are closely implicated human health diseases. Sleep deprivation (SD) has become increasingly common modern society, partly owing to rising pressure of work diversification entertainment. It is well documented that sleep loss significant cause various adverse outcomes on including immune-related metabolic Furthermore, accumulating evidence suggests gut dysbiosis associated with SD-induced In this review, we summarize caused by SD succedent diseases ranging from immune system organs highlight critical roles The implications possible strategies alleviate SD-related also provided.

Language: Английский

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The evaluation of catechins reducing heterocyclic aromatic amine formation: Structure-activity relationship and mechanism speculation

Current Research in Food Science, Journal Year: 2024, Volume and Issue: 8, P. 100727 - 100727

Published: Jan. 1, 2024

The favorable inhibitory effect of tea polyphenols on heterocyclic aromatic amines (HAAs) has been confirmed in many past studies. objective this study was to investigate the structure-activity relationship catechins that act as inhibitors HAA formation chemical models. Two kinds quantitative models for catechin-inhibiting-HAA were established. We chose two HAAs including 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), five epigallocatechin gallate (EGCG), epicatechin (ECG), (EGC), (EC), catechin (C). following order: EGCG > ECG EGC C EC. Thereinto, showed dramatically better inhibition PhIP MeIQx, especially EGCG. Further, mechanisms speculated by correlation analysis. free radical-scavenging ability predicted be most relevant ECG, EGC, EC HAAs. Differently, phenylacetaldehyde-trapping might more important mechanism inhibiting model system. This may bring a broader idea controlling according structure catechins.

Language: Английский

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Exploring the mechanism of flavonoids modification by dimerization strategies and their potential to enhance biological activity

Food Chemistry, Journal Year: 2024, Volume and Issue: 467, P. 142266 - 142266

Published: Nov. 27, 2024

Language: Английский

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Regulation of Hazelnut Leaf Polyphenols on Oxidative Stress in Chronic Alcoholic Liver Injury

eFood, Journal Year: 2025, Volume and Issue: 6(3)

Published: April 14, 2025

ABSTRACT This study aims to investigate the role of hazelnut leaf polyphenols (HLP) in regulating chronic alcoholic liver damage (CALD) and explore its possible molecular mechanisms. By measuring scavenging rates DPPH·, ABTS + , ·OH, as well reducing power total antioxidant capacity, activity HLP was evaluated. Both vivo vitro experiments were conducted examine effects on CALD. The results showed that exhibits strong within a certain concentration range, can regulate ethanol‐induced oxidative stress levels LO2 cells. Additionally, improves function by modulating Nrf2/Keap1 pathway, ALT AST mice, correcting body's redox imbalance. protective effect helps shield from damage, revealing possess potent properties significantly improve

Language: Английский

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Intergenerational inheritance of quercetin-induced abnormal immunity in mice

Critical Reviews in Food Science and Nutrition, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 12

Published: March 9, 2025

Quercetin, a dietary flavonol enriched in food, regulates immune-related models through epigenetic modifications. However, few studies have explored the transmission of regulatory effects across generations to progeny. Here, we selected Escherichia coli, conditional pathogen capable causing gastrointestinal infections or various localized tissue and organ under specific conditions, as pathogenic strain infect mice. We provide evidence that quercetin can not only induce responsiveness changes against systemic E. coli infection directly exposed organisms, but also subsequent transgenerational inheritance traits. Both parental male mice their progeny exhibited cellular phenotypic associated with metabolic alterations. Surprisingly, female treated (200 mg/kg) for six weeks negatively enhanced survival rate (1 × 108 CFU/mL) infection, concurrent an increase bacterial loads liver spleen. Serum TNF-α IL-1β levels significantly increased post-infection Our results first immunity driven by mammals attenuation protection infection.

Language: Английский

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Stability and degradation mechanism of (−)-epicatechin in thermal processing

Food Chemistry, Journal Year: 2024, Volume and Issue: 465, P. 142038 - 142038

Published: Nov. 13, 2024

(-)-Epicatechin (EC) is a commonly dietary phytochemical that presents multi-physiological activities on human health. Thermal processing common method to extract EC, albeit likely degrade EC considering its thermal instability. In this study, an 85-min non-durable bathing incubation assay was designed simulate the state of in boiling water while cooking. Monitoring degradation products performed using ultra-performance liquid chromatography combined with electrospray ionization quadrupole tandem mass spectrometric detection (UPLC-ESI-TSQ-MS/MS). The results revealed ca. 65.2 % loss detected first 10 min, and over 99.5 degraded within 30 min. A total 22 were identified based retention time, full MS data be comprehensively reported. Isomerization, oxidation, hydroxylation, dimerization, ring cleavage main chemical reactions occurred for aqueous solution.

Language: Английский

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Assessing the Effects of Dietary Tea Polyphenols on the Gut Microbiota of Loaches (Paramisgurnus dabryanus) under Chronic Ammonia Nitrogen Stress

Fishes, Journal Year: 2024, Volume and Issue: 9(5), P. 180 - 180

Published: May 15, 2024

This study examined the impact of tea polyphenols (TPs) on intestinal flora loaches (Paramisgurnus dabryanus) under chronic ammonia nitrogen stress using high-throughput sequencing. Two groups 600 were studied over one month, and they separated into a control group polyphenol group. Alpha beta diversity analyses showed diverse bacterial communities, with significant differences in abundance uniformity observed initially but not between sampling time points. Cluster revealed distinct microbial communities groups. A predictive function analysis indicated enrichment pathways related to amino acid nucleotide biosynthesis. These findings offer initial insights how may affect stress.

Language: Английский

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The Nexus between Polyphenols and Gut Microbiota and Their Interplay in Human Health: A Brief Review

Journal of Natural Remedies, Journal Year: 2024, Volume and Issue: unknown, P. 1895 - 1908

Published: Oct. 7, 2024

Polyphenols are a broad class of naturally occurring substances in plants and have drawn extensive attention as they may possess promising health-promoting benefits. Recently, gut microbiota polyphenol interactions been directly linked to the well-being humans. The classification, sources, polyphenols with presented this review, highlighting their key health benefits undergo complex transformations within gastrointestinal tract interact microbiota, varied collection bacteria living digestive system. substantially influence composition, functioning, metabolic activity, diversity. Research indicates that prebiotic-like properties, favouring Lactobacilli Bifidobacteria growth, among other beneficial bacteria. fermentation is aided by these bacteria, which produce bioactive metabolites improve human various ways. Moreover, alteration microbiology caused has improvements several outcomes, including enhanced health, fortified immunological function, decreased susceptibility chronic conditions like heart disease certain forms cancer. In summary, intriguing relationship between significant implications for Understanding relationships can open door tailored dietary treatments development functional foods support balanced general well-being.

Language: Английский

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Non-invasive anticipation of infusion taste in fine-manipulated green teas through hyperspectral appearance analysis guided by ECG content

Food Chemistry, Journal Year: 2024, Volume and Issue: 458, P. 140254 - 140254

Published: June 27, 2024

Language: Английский

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