Retracted: COVID‐19 mortality and its predictors in the elderly: A systematic review

Health Science Reports, Journal Year: 2022, Volume and Issue: 5(3)

Published: May 1, 2022

Abstract Background and Aims Older people have higher rates of comorbidities may experience more severe inflammatory responses; therefore, are at risk death. Herein, we aimed to systematically review the mortality in coronavirus disease 2019 (COVID‐19) patients its predictors this age group. Methods We searched PubMed, Web Science, Science Direct using relevant keywords. Retrieved records underwent a two‐step screening process consisting title/abstract full‐text screenings identify eligible studies. Results Summarizing findings 35 studies demonstrated that older compared younger population. A articles revealed increasing age, body mass index, male gender, dementia, impairment or dependency daily activities, presence consolidations on chest X‐ray, hypoxemic respiratory failure, lower oxygen saturation admission were factors for High d ‐dimer levels, 25‐hydroxy vitamin D serum deficiencies, high C‐reactive protein (≥5 mg/L) levels plus any other abnormalities lymphocyte, blood urea nitrogen lactate dehydrogenase, platelet count poor prognosis elderly. Studies also shown previous treatment with renin–angiotensin–aldosterone system inhibitors, pharmacological treatments disorders, antibiotics, corticosteroids, K antagonist, antihistamines, azithromycin, Itolizumab (an anti‐CD6 monoclonal antibody) combination antivirals reduces COVID‐19 worsening mortality. Vaccination against seasonal influenza might reduce Conclusion Overall, critical consideration is necessary care management aged population considering drastic contrasts manifestation groups. Mortality from independently associated patient's age. Elderly vulnerable outcomes. Thus, strict preventive measures, timely diagnosis, aggressive therapeutic/nontherapeutic great importance acute distress syndrome complications people.

Language: Английский

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Outcomes of patients with HIV and COVID-19 co-infection: a systematic review and meta-analysis

AIDS Research and Therapy, Journal Year: 2022, Volume and Issue: 19(1)

Published: Jan. 14, 2022

Abstract Background Data on the association of human immunodeficiency virus (HIV) infection with adverse outcomes in patients COVID-19 are conflicting. This systematic review and meta-analysis aimed to summarize available information risk hospitalization, severe disease, death attributable HIV COVID-19. Methods PubMed, EMBASE, Web Science, SCOPUS were searched through October 25, 2021, identify relevant studies, without language restriction. A random-effects model was used pool estimates. Results We included 44 studies reporting from 38,971,065 The pooled prevalence among 26.9 ‰ (95% CI 22.7–31.3) significantly higher conducted Africa compared those elsewhere (118.5‰ [95% 84.8–156.9, 11 studies] vs 10.9‰ 8.8–13.2, 27 studies]). In analyses unadjusted odds ratio, HIV-positive individuals more likely be admitted hospital (OR: 1.49; 95% 1.01–2.21, 6 studies) HIV-negative individuals. adjusted (for age sex) analyses, associated an increased (hazard ratio: 1.76, 1.31–2.35, 2 studies). However, not severity disease 1.28; 0.77–2.13, 13 studies), or 0.81; 0.47; 1.41, 23 ratio. Conclusion Our findings suggest that have admission for seems independently mortality patient analysis. this evidence derived only two studies.

Language: Английский

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The impacts of COVID-19 pandemic on service delivery and treatment outcomes in people living with HIV: a systematic review

AIDS Research and Therapy, Journal Year: 2023, Volume and Issue: 20(1)

Published: Jan. 6, 2023

Abstract Introduction The COVID-19 epidemic and various control mitigation measures to combat the widespread outbreak of disease may affect other parts health care systems. There is a concern that pandemic could disrupt HIV services. Therefore, this study aimed systematically evaluate effect on service delivery treatment outcomes in people with HIV. Methods In study, systematic search was conducted using keywords online databases including Scopus, PubMed, Web Science, Cochrane databases. retrieved articles underwent two-step title/abstract full-text review process, eligible papers were selected included qualitative synthesis. Result We 16 studies out 529 records met inclusion criteria for review. Study populations either HIV-positive patients or clinics healthcare providers. Most focused adhering obtaining medication attending clinical appointments their decrement during pandemic. Other aspects (alternative settings, viral suppression, psychological care, etc.) discussed lesser extent by studies. Conclusion Interruption in-person visits medical follow-up services, loss adherence treatment, subsequent increase mortality due complications PLHIV have led growing concerns. challenges disorders such as anxiety depression, an substance abuse, rise experienced stigma discrimination. However, use telemedicine some countries helps alleviate situation recommended similar settings future.

Language: Английский

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The effects of hyperbaric oxygen therapy (HBOT) on coronavirus disease-2019 (COVID-19): a systematic review

European journal of medical research, Journal Year: 2021, Volume and Issue: 26(1)

Published: Aug. 19, 2021

Abstract Background Oxygenation serves as a cornerstone in the treatment of COVID-19, and several methods have been extensively studied so far. Herein, we aimed to systematically review studies discussing hyperbaric oxygen therapy (HBOT) examine its reported efficacy adverse events patients with COVID-19. Methods We searched retrieved relevant articles using keywords on online databases, including PubMed, Scopus, Embase, Web Science, Cochrane databases up April 11th, 2021. The records underwent two-step title/abstract full-text screening process, eligible papers were identified. National Institutes health (NIH) quality assessment tool was used for this study. This study registered International Prospective Register Systematic Reviews (PROSPERO) ID CRD42021269821. Results Eight from three countries included. All included had good fair scores, no poor systematic (Good: n = 5, Fair: 3). Studies divided into clinical trials case reports/series. Most HBOT less than 1.5–2 absolute atmospheres (ATA) 90 min sessions thereafter decreased 60 min. Trials demonstrated most recovered after receiving HBOT, blood saturation increased HBOT. Conclusion Overall, seems be safe effective oxygenation method However, there is limited knowledge evidence regarding effects mechanism COVID-19 treatment, further evaluations require extensive well-designed studies.

Language: Английский

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The clinical outcomes of COVID‐19 in HIV‐positive patients: A systematic review of current evidence

Immunity Inflammation and Disease, Journal Year: 2021, Volume and Issue: 9(4), P. 1160 - 1185

Published: July 29, 2021

Patients with chronic underlying diseases are more susceptible to coronavirus disease 2019 (COVID-19) complications. Recent studies showed people living HIV (PLWH) not at greater risk than the general population. Few have reviewed impacts of COVID-19 on PLWH. The purpose this systematic review was investigate impact patients infected HIV.We executed a search using four databases PubMed, Scopus, Science Direct, and Web screened records in two steps based their title/abstract full text. This study follows Preferred Reporting Items for Systematic Reviews Meta-Analyses (PRISMA) checklist elevate validity reliability its results.We 36 studies. patients' age above 20 years all In almost studies, inflammatory parameters were reported high. most completely recovered from COVID 19 infection. Although CD4 count recorded minimum level as 12 cells/µl.Based current review, we concluded that advanced stages (3 or 4) disease, whose counts low, may show less severe infection symptoms. Similarly, Interference can reduce severity immune reactions subsequent cytokine storms consequently mitigate Therefore, majority no symptoms

Language: Английский

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Retracted: Mucormycosis infection in patients with COVID‐19: A systematic review

Health Science Reports, Journal Year: 2022, Volume and Issue: 5(2)

Published: Feb. 28, 2022

Several reports previously described mucormycosis co-infection in patients with COVID-19. As and COVID-19 might adversely affect patients' outcomes, we aimed to systematically review the related evidence subsequent outcomes.

Language: Английский

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Risk of mortality in HIV-infected COVID-19 patients: A systematic review and meta-analysis

Journal of Infection and Public Health, Journal Year: 2022, Volume and Issue: 15(6), P. 654 - 661

Published: May 16, 2022

The relationship between HIV infection and COVID-19 clinical outcomes remains a significant public health research problem. We aimed to determine the association of comorbidity with mortality.We searched PubMed, Google Scholar World Health Organization library databases for relevant studies. All searches were conducted from 1st 7th December 2021. Title, abstract full text screening was following Preferred Reporting Items Systematic Reviews Meta-Analyses guidelines. relative risk mortality in HIV-infected patients computed using random-effects model. analyses performed Meta Metasens statistical packages available R version 4.2.1 software package. quality included studies assessed GRADE approach, Egger's test employed bias.A total 16 this review. Among infection, rate due 7.97% (4 287/53,801), among without 0.69% (127, 961/18, 513, 747). In random effects model, we found no statistically (RR 1.07, 95% CI 0.86-1.32). between-studies heterogeneity substantial (I2 = 91%, P < 0.01), while publication bias not significant.Findings did link an increased mortality. Our results add conflicting data on infection.

Language: Английский

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Retracted: Internet of things in the management of chronic diseases during the COVID‐19 pandemic: A systematic review

Health Science Reports, Journal Year: 2022, Volume and Issue: 5(2)

Published: March 1, 2022

The use of new technologies such as the Internet Things (IoT) in management chronic diseases, especially COVID pandemics, could be a life-saving appliance for public health practice. purpose current study is to identify applications and capability IoT digital COVID-19 pandemic.

Language: Английский

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COVID‐19 in HIV‐positive patients: A systematic review of case reports and case series

Journal of Clinical Laboratory Analysis, Journal Year: 2022, Volume and Issue: 36(4)

Published: Feb. 20, 2022

Abstract Introduction Coronavirus disease 2019 (COVID‐19) and acquired immune deficiency syndrome (AIDS) are two viral diseases for which there currently no definitive treatments. Nowadays, because of the health system's focus on COVID‐19 epidemic, control human immunodeficiency virus (HIV) has received less attention. In this review, we will discuss characteristics in HIV‐positive patients. Material Methods Using PRISMA guideline, databases Scopus, PubMed, Web Science were searched systematically from January 1, to February 24, 2021. The following keywords used: “Human Immunodeficiency Virus,” “acquired syndrome,” “HIV,” “AIDS,” “COVID‐19,” “severe acute respiratory coronavirus 2,” “novel coronavirus,” “SARS‐CoV‐2,” “nCoV disease,” “SARS2,” “2019‐nCoV disease.” Results Twenty‐one percent studies conducted USA ( n = 13), 16% China 10), 13% Italy 8), respectively. majority patients men (74.3%). Tenofovir disoproxil fumarate was used 47.4% patients, emtricitabine 58.4%, lamivudine 34.8% treat HIV. Symptoms HIV with included coughing (81.3%), fever (62.8%), dyspnea (60%). Hydroxychloroquine (39.34%) azithromycin (36.58%) common treatment options COVID‐19. total death rate about 9%. Conclusion current systematic demonstrated that co‐infected have high comorbidity hypertension diabetes mellitus. HIV/COVID‐19 co‐infection might negatively influenced diagnosis, indicates need regularly screen pandemic.

Language: Английский

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The Impact of COVID-19 Pandemic on the Levels of Physical Activity: A Systematic Review

Infectious Disorders - Drug Targets, Journal Year: 2023, Volume and Issue: 23(4)

Published: Jan. 23, 2023

Introduction: Earlier studies demonstrated a decreased level of physical activity (PA) during the COVID-19 pandemic. Therefore, we aimed to systematically review relevant among various age groups and explore impact on mental health. Methods: We searched retrieved all articles using keywords online databases PubMed, Scopus, Cochrane from start pandemic until May 3rd, 2021. A two-phase screening process identified records was carried out shortlist most studies. First, were evaluated based their title/abstract, then full-text included thoroughly read. The eligible eligibility criteria in this review. Results: total 57 criteria. Lockdowns infection with SARS-CoV-2 have led PA general population compared prepandemic era. Men had significantly less women some studies, probably due higher pre-pandemic PA. those chronic diseases also diminished, putting them at risk cardiovascular incidents. Sedentary lifestyles dominated people’s life, including adolescents university students. increased levels health issues, such as depression, anxiety, occupational stress, been suggested contribute On other hand, appeared lead more issues. Fortunately, decreasing trend seemed taper towards end quarantines. Conclusion: Overall, subsequent quarantines reduced both sexes detrimental effects people's suggest countries implement strategies alleviate restrictions encourage people exercise safe environments prepare healthy routines for themselves.

Language: Английский

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