Additive manufacturing of sustainable biomaterials for biomedical applications

Asian Journal of Pharmaceutical Sciences, Journal Year: 2023, Volume and Issue: 18(3), P. 100812 - 100812

Published: April 27, 2023

Biopolymers are promising environmentally benign materials applicable in multifarious applications. They especially favorable implantable biomedical devices thanks to their excellent unique properties, including bioactivity, renewability, bioresorbability, biocompatibility, biodegradability and hydrophilicity. Additive manufacturing (AM) is a flexible intricate technology, which widely used fabricate biopolymer-based customized products structures for advanced healthcare systems. Three-dimensional (3D) printing of these sustainable applied functional clinical settings wound dressing, drug delivery systems, medical implants tissue engineering. The present review highlights recent advancements different types biopolymers, such as proteins polysaccharides, employed develop by using extrusion, vat polymerization, laser inkjet 3D techniques addition normal bioprinting four-dimensional (4D) techniques. This also incorporates the influence nanoparticles on biological mechanical performances 3D-printed scaffolds. work addresses current challenges well future developments friendly polymeric manufactured through AM Ideally, there need more focused research adequate blending biodegradable biopolymers achieving useful results targeted areas. We envision that composites have potential revolutionize sector near future.

Language: Английский

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Collagen-Based Biomaterials for Tissue Engineering

ACS Biomaterials Science & Engineering, Journal Year: 2023, Volume and Issue: 9(3), P. 1132 - 1150

Published: Feb. 17, 2023

Collagen is commonly used as a regenerative biomaterial due to its excellent biocompatibility and wide distribution in tissues. Different kinds of hybridization or cross-links are favored offer improvements satisfy various needs biomedical applications. Previous reviews have been made introduce the sources structures collagen. In addition, biological mechanical properties collagen-based biomaterials, their modification application forms, interactions with host tissues pinpointed. However, there still no review about biomaterials for tissue engineering. Therefore, we aim summarize discuss progress materials regeneration applications this review. We focus on utilization bones, cartilages, skin, dental, neuron, cornea, urological hope these experiences outcomes can provide inspiration practical techniques future development related fields. Moreover, improving directions challenges proposed well.

Language: Английский

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Natural Piezoelectric Biomaterials: A Biocompatible and Sustainable Building Block for Biomedical Devices

ACS Nano, Journal Year: 2022, Volume and Issue: 16(11), P. 17708 - 17728

Published: Nov. 10, 2022

The piezoelectric effect has been widely observed in biological systems, and its applications biomedical field are emerging. Recent advances of wearable implantable devices bring promise as well requirements for the materials building blocks. Owing to their biocompatibility, biosafety, environmental sustainability, natural biomaterials known a promising candidate this emerging field, with potential replace conventional ceramics synthetic polymers. Herein, we provide thorough review recent progresses research on five major types including amino acids, peptides, proteins, viruses, polysaccharides. Our discussion focuses structure- phase-related properties fabrication strategies achieve desired phases. We compare analyze performance further introduce comment approaches improve property. Representative group functional energy harvesting, sensing, tissue engineering also discussed. envision that molecular-level understanding effect, response improvement, large-scale manufacturing three main challenges development opportunities interdisciplinary field.

Language: Английский

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A review on four-dimensional (4D) bioprinting in pursuit of advanced tissue engineering applications

Bioprinting, Journal Year: 2022, Volume and Issue: 27, P. e00203 - e00203

Published: March 30, 2022

Language: Английский

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Synthetic extracellular matrices with function-encoding peptides

Nature Reviews Bioengineering, Journal Year: 2023, Volume and Issue: 1(7), P. 518 - 536

Published: April 25, 2023

Language: Английский

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A Review of Recent Progress on Collagen‐Based Biomaterials

Advanced Healthcare Materials, Journal Year: 2022, Volume and Issue: 12(16)

Published: Nov. 15, 2022

Abstract Since the 2010s, demand for healthcare models has exceeded prevailing resources available due to rapid increase in aging population China. However, a significant gap development of biomedical materials remains, especially between China and western developed countries. Collagen is major protein extracellular matrix (ECM) been extensively applied medical fields. Collagen‐based biomaterials (CBBs) are used prepare dressings dermal substitutes, surgical sutures, plasma tissue‐engineered scaffolds, drug delivery systems; this attributed their exceptional biocompatibility, biodegradability, hypoimmunogenicity, coordination collagen hosts tissues. This review provides thorough strides CBB structures, crosslinking forming technologies, real‐world applications. First, natural origin specific structures animal‐derived non‐animal‐derived introduced compared. Second, methods technologies CBBs across board discussed. Third, several examples considered demonstrate practical use highlight cautionary notes. Finally, underlying directions from an interdisciplinary perspective outlined. aims provide comprehensive mechanisms by which can be uniquely practically as advanced biomaterial, hence providing options augmenting its

Language: Английский

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Materials-based drug delivery approaches: Recent advances and future perspectives

Green Processing and Synthesis, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract Materials-based drug delivery approaches have garnered substantial attention in recent years due to their potential revolutionize pharmaceutical interventions. This abstract provides a concise overview of advancements and future prospects this rapidly evolving field. Materials such as nanoparticles, liposomes, polymers, hydrogels emerged versatile carriers for delivery. These materials facilitate precise control over release kinetics, enabling targeted sustained therapeutic effects. Smart with responsiveness external stimuli or physiological conditions further enhanced precision. Personalized medicine are gaining traction, tailoring systems individual patient profiles needs. The horizon materials-based is bright. Ongoing research focused on refining material design, streamlining production processes, ensuring safety profiles. Collaborative efforts among researchers, clinicians, industry stakeholders crucial translating these into clinical practice. Additionally, the convergence diagnostics imaging holds immense personalized efficient healthcare solutions. As continues evolve, it stands poised reshape landscape pharmaceuticals, offering promise more effective patient-centered therapies wide range medical conditions.

Language: Английский

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Tissue engineering applications of recombinant human collagen: a review of recent progress

Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 12

Published: Feb. 14, 2024

With the rapid development of synthetic biology, recombinant human collagen has emerged as a cutting-edge biological material globally. Its innovative applications in fields science and medicine have opened new horizons biomedical research. Recombinant stands out highly promising biomaterial, playing pivotal role crucial areas such wound healing, stroma regeneration, orthopedics. However, realizing its full potential by efficiently delivering it for optimal therapeutic outcomes remains formidable challenge. This review provides comprehensive overview systems, focusing on resolving this issue. Additionally, encompasses exploration 3D printing technologies incorporating to address some urgent clinical challenges regenerative repair future. The primary aim also is spotlight advancements realm biomaterials utilizing collagen, with intention fostering additional innovation making significant contributions enhancement biomaterials, methodologies, overall patient outcomes.

Language: Английский

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Collagen-Based Scaffolds for Chronic Skin Wound Treatment

Gels, Journal Year: 2024, Volume and Issue: 10(2), P. 137 - 137

Published: Feb. 8, 2024

Chronic wounds, commonly known as ulcers, represent a significant challenge to public health, impacting millions of individuals every year and imposing financial burden on the global health system. wounds result from interruption natural wound-healing process due internal and/or external factors, resulting in slow or nonexistent recovery. Conventional medical approaches are often inadequate deal with chronic necessitating exploration new methods facilitate rapid effective healing. In recent years, regenerative medicine tissue engineering have emerged promising avenues encourage regeneration. These aim achieve anatomical functional restoration affected area through polymeric components, such scaffolds hydrogels. This review explores collagen-based biomaterials potential therapeutic interventions for skin specifically focusing infective diabetic ulcers. Hence, different described classified an action-mechanism basis. Understanding issues preventing wound healing identifying alternatives could indicate best way optimize units promote more direct efficient

Language: Английский

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Bioactive polymers: A comprehensive review on bone grafting biomaterials

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 278, P. 134615 - 134615

Published: Aug. 10, 2024

Language: Английский

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