Life Sciences, Journal Year: 2024, Volume and Issue: 358, P. 123199 - 123199
Published: Nov. 1, 2024
Language: Английский
Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(6), P. 699 - 699
Published: May 23, 2024
Malaria poses a global threat to human health, with millions of cases and thousands deaths each year, mainly affecting developing countries in tropical subtropical regions. Malaria’s causative agent is Plasmodium species, generally transmitted the hematophagous act female Anopheles sp. mosquitoes. The main approaches fighting malaria are eliminating parasite through drug treatments preventing transmission vector control. However, resistance current strategies set challenge. In response loss efficacy environmental impact pesticides, focus shifted search for biocompatible products that could be antimalarial. Plant derivatives have millennial application traditional medicine, including treatment malaria, show toxic effects towards mosquito, aside from being accessible affordable. Its disadvantage lies type administration because green chemical compounds rapidly degrade. nanoformulation these can improve bioavailability, solubility, efficacy. Thus, nanotechnology-based development plant represents relevant tool fight against malaria. We aim review nanoparticles synthesized extracts on while outlining nanotechnology synthesis prevention strategies.
Language: Английский
Citations
2
Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 67(11), P. 8519 - 8544
Published: May 24, 2024
In the ever-evolving landscape of cancer research, immuno-oncology stands as a beacon hope, offering novel avenues for treatment. This study capitalizes on vast repository immuno-oncology-related scientific documents within CAS Content Collection, totaling over 350,000, encompassing journals and patents. Through pioneering approach melding natural language processing with indexing system, we unveil 300 emerging concepts, depicted in comprehensive "Trend Landscape Map". These spanning therapeutic targets, biomarkers, types cancers among others, are hierarchically organized into eight major categories. Delving deeper, our analysis furnishes detailed quantitative metrics showcasing growth trends past three years. Our findings not only provide valuable insights guiding future research endeavors but also underscore merit tapping unparalleled breadth existing information to derive profound insights.
Language: Английский
Citations
2
Biochemistry and Biophysics Reports, Journal Year: 2024, Volume and Issue: 40, P. 101877 - 101877
Published: Nov. 17, 2024
Language: Английский
Citations
2
International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 3677 - 3695
Published: April 1, 2024
Bladder cancer, a prevalent malignant neoplasm of the urinary tract, exhibits escalating morbidity and mortality rates.Current diagnosis standards rely on invasive costly cystoscopy histopathology, underscoring urgency for non-invasive, high-throughput, cost-effective novel diagnostic techniques to ensure timely detection standardized treatment.Recent years have witnessed rise exosome research in bladder cancer studies.Exosomes contain abundant bioactive molecules that can help elucidate intricate mechanisms underlying pathogenesis metastasis.Exosomes hold potential as biomarkers early while also serving targeted drug delivery vehicles enhance treatment efficacy mitigate adverse effects.Furthermore, analyses offer insights into complex molecular signaling networks implicated progression, revealing therapeutic targets.This review provides comprehensive overview isolation highlights promising clinical utility exosomes both applications management.
Language: Английский
Citations
1
Life Sciences, Journal Year: 2024, Volume and Issue: 358, P. 123199 - 123199
Published: Nov. 1, 2024
Language: Английский
Citations
1