Metabolomics,
Journal Year:
2023,
Volume and Issue:
19(12)
Published: Nov. 17, 2023
The
prevalence
of
hypertension
and
obesity
are
a
worldwide
concern.Assess
the
metabolites
profile
after
intervention
with
mixed
dietary
fiber
in
overweight
obese
normotensive
women.This
is
randomized
double
blind
placebo-controlled
study.
Through
simple
randomization
process,
two
groups
were
allocated,
eleven
women
(group
1)
receiving
12
g
thirteen
2)
placebo
(corn
starch)
for
eight
weeks.
Anthropometric
biochemical
tests
lifestyle
analyzed.
As
evaluation
metabolomics,
used
1H
NMR.
data
matrix
generated
96
samples
225
variables,
which
was
exported
ASCII
format
"The
Unscrumbler"
statistics
software
(version
9.7,
CAMO
Process).After
fiber,
significant
differences
observed
between
main
types
metabolites,
referring
to
increase
relative
peak
areas
three
HDL
4.94
ppm
(0.0086*),
1.28
(0
.0337*),
0.88
(0.0224*)
an
α-glucose
metabolite
4.90
(0.0106)
reduction
systolic
blood
pressure
(SBP)
(0.0292*)
7
mmHg
reference
range
group
there
SBP
(0.0118*)
4
choline
3.65
(0.0266*),
does
not
call
into
question
validity
these
results
literature.The
synergism
functions
statistically
highlighted
contributed
prevention
women.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Nov. 15, 2024
The
association
between
subjective
walking
speed
and
metabolic
diseases
has
received
limited
attention,
particularly
in
individuals
with
obesity.
We
aimed
to
clarify
this
using
comprehensive
health
checkup
data
of
participants
In
total,
8578
a
body
mass
index
≥
25.0
kg/m2,
9626
waist
circumference
85
cm
men
90
women,
6742
who
met
both
criteria
were
included
cross-sectional
analysis.
Subjective
was
investigated
the
question
"Is
your
faster
than
those
age
sex?"
examination
questionnaire.
Metabolic
defined
according
guidelines
for
each
disease,
modified
Poisson
regression
analyses
performed.
model
adjusted
sex,
obesity
based
on
fast
showed
significantly
lower
risk
diabetes
mellitus
(risk
ratio
[RR]
0.70;
95%
CI
0.63–0.77)
dyslipidemia
(RR
0.97;
0.94–1.00).
Similarly,
among
circumference,
significant
negative
hypertension
0.94;
0.90–0.97
RR
0.95;
0.92–0.99,
respectively),
0.64–0.77
0.63–0.77,
0.96;
0.94–0.99
0.94–0.99,
respectively).
Thus,
obesity,
odds
if
their
fast.
This
study
contributes
earlier
prevention
cascade
that
begin
Diabetes Obesity and Metabolism,
Journal Year:
2024,
Volume and Issue:
27(2), P. 683 - 696
Published: Nov. 11, 2024
Metabolic
dysfunction-associated
steatotic
liver
disease
(MASLD)
and
obesity
increases
risk
of
cardiovascular
disease.
This
cohort
study
examines
the
prognostic
value
MASLD,
across
body
weight
categories,
in
a
secondary
preventative
acute
myocardial
infarction
(AMI)
cohort.
Metabolomics,
Journal Year:
2023,
Volume and Issue:
19(12)
Published: Nov. 17, 2023
The
prevalence
of
hypertension
and
obesity
are
a
worldwide
concern.Assess
the
metabolites
profile
after
intervention
with
mixed
dietary
fiber
in
overweight
obese
normotensive
women.This
is
randomized
double
blind
placebo-controlled
study.
Through
simple
randomization
process,
two
groups
were
allocated,
eleven
women
(group
1)
receiving
12
g
thirteen
2)
placebo
(corn
starch)
for
eight
weeks.
Anthropometric
biochemical
tests
lifestyle
analyzed.
As
evaluation
metabolomics,
used
1H
NMR.
data
matrix
generated
96
samples
225
variables,
which
was
exported
ASCII
format
"The
Unscrumbler"
statistics
software
(version
9.7,
CAMO
Process).After
fiber,
significant
differences
observed
between
main
types
metabolites,
referring
to
increase
relative
peak
areas
three
HDL
4.94
ppm
(0.0086*),
1.28
(0
.0337*),
0.88
(0.0224*)
an
α-glucose
metabolite
4.90
(0.0106)
reduction
systolic
blood
pressure
(SBP)
(0.0292*)
7
mmHg
reference
range
group
there
SBP
(0.0118*)
4
choline
3.65
(0.0266*),
does
not
call
into
question
validity
these
results
literature.The
synergism
functions
statistically
highlighted
contributed
prevention
women.
