ACS symposium series, Journal Year: 2024, Volume and Issue: unknown, P. 339 - 339
Published: March 5, 2024
Language: Английский
ACS symposium series, Journal Year: 2024, Volume and Issue: unknown, P. 339 - 339
Published: March 5, 2024
Language: Английский
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(11), P. 5842 - 5842
Published: May 27, 2024
This study provides a brief discussion of the major nanopharmaceuticals formulations as well impact nanotechnology on future pharmaceuticals. Effective and eco-friendly strategies biofabrication are also highlighted. Modern approaches to designing pharmaceutical nanoformulations (e.g., 3D printing, Phyto-Nanotechnology, Biomimetics/Bioinspiration, etc.) outlined. paper discusses need use natural resources for “green” design new with therapeutic efficiency. Nanopharmaceuticals research is still in its early stages, preparation nanomaterials must be carefully considered. Therefore, safety long-term effects not overlooked. The testing represents an essential point their further applications. Vegetal scaffolds obtained by decellularizing plant leaves represent valuable, bioinspired model nanopharmaceutical that avoids using animals. Nanoformulations critical various fields, especially pharmacy, medicine, agriculture, material science, due unique properties advantages over conventional allows improved solubility, bioavailability, targeted drug delivery, controlled release, reduced toxicity. have transitioned from experimental stages being vital component clinical practice, significantly improving outcomes medical fields cancer treatment, infectious diseases, neurological disorders, personalized advanced diagnostics. Here key points highlighting importance. significant challenges, opportunities, directions mentioned final section.
Language: Английский
Citations
27Hybrid Advances, Journal Year: 2025, Volume and Issue: unknown, P. 100406 - 100406
Published: Feb. 1, 2025
Language: Английский
Citations
6Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 514, P. 215926 - 215926
Published: May 9, 2024
Language: Английский
Citations
12Advanced Science, Journal Year: 2024, Volume and Issue: 11(38)
Published: Aug. 5, 2024
As a form of dementia, Alzheimer's disease (AD) suffers from no efficacious cure, yet AD treatment is still imperative, as it ameliorates the symptoms or prevents deteriorating maintains current status to longest extent. The human brain most sensitive and complex organ in body, which protected by blood-brain barrier (BBB). This induces difficulty curing drugs nanomaterials that are much inhibited reaching lesion site. Thus, BBB crossing capability drug delivery system remains significant challenge development neurological therapeutics. Fortunately, nano-enabled systems possess promising potential achieve multifunctional diagnostics/therapeutics against various targets owing their intriguing advantages nanocarriers, including easy multifunctionalization on surfaces, high surface-to-volume ratio with large payloads, ability cross BBB, making them capable conquering limitations conventional candidates. review, focuses diagnosis treatment, will provide an insightful vision conducive AD-related nanomaterials.
Language: Английский
Citations
7International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown, P. 125380 - 125380
Published: Feb. 1, 2025
Language: Английский
Citations
1Microporous and Mesoporous Materials, Journal Year: 2023, Volume and Issue: 366, P. 112934 - 112934
Published: Dec. 22, 2023
Language: Английский
Citations
15Advanced Functional Materials, Journal Year: 2023, Volume and Issue: 34(3)
Published: Oct. 15, 2023
Abstract Recently, neurological disorders have led to a growing global burden of fatalities and disabilities. The limited capacity for natural self‐regeneration poses significant challenge in repairing nervous system injuries, which is closely related the complex microenvironment nonregenerative nature neurons. Metal–organic frameworks (MOFs), with their distinctive structure properties including high surface area, porosity, tunability, stimuli‐responsive behavior, biocompatibility, biodegradability, stand as an auspicious platform devising therapeutic strategies aiming at nerve regeneration repair. By taking advantage these characteristics, researchers opportunity explore innovative methods endogenous stimulation, magnetic response therapy, phototherapy, ultrasound drug delivery systems treatment diseases. Moreover, MOFs‐based stem cell therapy also developed inhibit neuroinflammation oxidative stress, promote axon growth, regulate differentiation, regeneration, finally restore function injured nerves. In this paper, preparation strategy biological characteristics MOFs, highlighting applications injuries treating neural cells presented. Finally, outlook on future development challenges field neuroscience concerning MOFs provided.
Language: Английский
Citations
13Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(19), P. 4553 - 4573
Published: Jan. 1, 2024
Neurodegenerative diseases (amyloid such as Alzheimer's and Parkinson's), stemming from protein misfolding aggregation, encompass a spectrum of disorders with severe systemic implications. Timely detection is pivotal in managing these owing to their significant impact on organ function high mortality rates. The diverse array amyloid disorders, spanning localized manifestations, underscores the complexity conditions highlights need for advanced methods. Traditional approaches have focused identifying biomarkers using imaging techniques (PET MRI) or invasive procedures. However, recent efforts use metal-organic frameworks (MOFs), versatile class materials known unique properties, revolutionizing disease detection. porosity, customizable structures, biocompatibility MOFs enable integration biomolecules, laying groundwork highly sensitive specific biosensors. These sensors been employed electrochemical photophysical that target species under neurodegenerative conditions. adaptability allows precise quantification proteins, offering potential advancements early diagnosis management. This review article delves into how contribute detecting by categorizing uses based different sensing methods, (EC), electrochemiluminescence (ECL), fluorescence, Förster resonance energy transfer (FRET), up-conversion luminescence (ULRET), photoelectrochemical (PEC) sensing. drawbacks MOF biosensors challenges encountered field are also briefly explored our perspective.
Language: Английский
Citations
5Microchemical Journal, Journal Year: 2024, Volume and Issue: 206, P. 111441 - 111441
Published: Aug. 16, 2024
Language: Английский
Citations
5Microchemical Journal, Journal Year: 2023, Volume and Issue: 197, P. 109852 - 109852
Published: Dec. 26, 2023
Language: Английский
Citations
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