A novel dual-function biomimetic approach for high throughput organic dye biodegradation and hydrogen peroxide sensing using a nanosized artificial peroxidase with ultra-improved substrate affinity and superb catalytic efficiency DOI
Saeed Reza Hormozi Jangi, Zahra Dehghani

Process Biochemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

A Review on the Recent Advances in Battery Development and Energy Storage Technologies DOI Creative Commons
George G. Njema,

Russel Ben O. Ouma,

Joshua K. Kibet

et al.

Journal of Renewable Energy, Journal Year: 2024, Volume and Issue: 2024, P. 1 - 35

Published: May 8, 2024

Energy storage is a more sustainable choice to meet net-zero carbon foot print and decarbonization of the environment in pursuit an energy independent future, green transition, uptake. The journey reduced greenhouse gas emissions, increased grid stability reliability, improved access security are result innovation systems. Renewable sources fundamentally intermittent, which means they rely on availability natural resources like sun wind rather than continuously producing energy. Due its ability address inherent intermittency renewable sources, manage peak demand, enhance make it possible integrate small-scale systems into grid, essential for continued development decentralization generation. Accordingly, effective system has been prompted by demand unlimited supply energy, primarily through harnessing solar, chemical, mechanical Nonetheless, order achieve transition mitigate climate risks resulting from use fossil-based fuels, robust necessary. Herein, need better, devices such as batteries, supercapacitors, bio-batteries critically reviewed. their low maintenance needs, supercapacitors facilities, most notably Moreover, possess charging discharging cycles, high power density, requirements, extended lifespan, environmentally friendly. On other hand, combining aluminum with nonaqueous charge materials conductive polymers each material’s unique capabilities could be crucial batteries. In general, density key component battery development, scientists constantly developing new methods technologies existing batteries proficient safe. This will design that powerful lighter range applications. When there imbalance between (ESS) offer way increasing effectiveness electrical They also play central role enhancing reliability excellence networks can deployed off-grid localities.

Language: Английский

Citations

62

Multi‐Mode/Signal Biosensors: Electrochemical Integrated Sensing Techniques DOI
Qingzhi Han, Haimei Wang, Haimei Wang

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: May 14, 2024

Abstract Electrochemical (EC) analysis has emerged as a high‐sensitivity, reliable, cost‐effective, and rapidly evolving technique that garnered significant attention across diverse domains. Furthermore, EC‐based techniques hold great potential for miniaturization integration. The integration of EC with mode/signal (such light, magnetic, thermal signals, etc.) provides unique opportunities biosensors to acquire more information through single sensing platform. By coupling multiple signals or processing them logically, the detection accuracy can be further improved, probability false positives negatives minimized. In this review, thorough multi‐ sensors in field is conducted, along their various (e.g., fluorescence, photothermal, colorimetry, microfluidic, etc.). aim delve into latest advances, applications, well challenges multi‐mode/signal biosensors, where utilization modalities helps enhance accuracy, sensitivity, selectivity. This review new insight synergistic effects integrating other techniques, aiming shed light on near‐future developments EC‐integrated biosensors.

Language: Английский

Citations

35

Chemically modified DNAzymes-based electrochemical sensor for binary and highly sensitive detection of reactive oxygen species DOI Creative Commons
Baoting Dou, Hui Shen, Zhimin Li

et al.

Chemical Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

A chemically modified DNAzyme-based electrochemical sensor was developed for binary and highly sensitive detection of reactive oxygen species.

Language: Английский

Citations

3

“Three-in-One” Plasmonic Au@PtOs Nanocluster Driven Lateral Flow Assay for Multimodal Cancer Exosome Biosensing DOI
Xiaorui Lin, Pengyou Zhou, Qing Li

et al.

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(26), P. 10686 - 10695

Published: June 17, 2024

Exploiting the multiple properties of nanozymes for multimode lateral flow assay (LFA) is urgently required to improve accuracy and versatility. Herein, we developed a novel plasmonic Au nanostar@PtOs nanocluster (Au@PtOs) as signal tag LFA detection. Based on PtOs bimetallic doping strategy, Au@PtOs can indicate both excellent SERS enhancement nanozyme catalytic activity. Meanwhile, displays better photothermal effect than that nanostars. Therefore, colorimetric/SERS/temperature three-mode signals be read out based nanocomposite. The was combined with applied breast cancer exosome detection limit mode 2.6 × 103/4.1 101/4.6 102 exosomes/μL, respectively, which much superior common nanoparticles (∼105 exosomes/μL). Moreover, fingerprint molecular recognition ability mode, phenotypes derived from different cell lines discriminated easily. convenient visual colorimetric sensitive SERS/temperature quantitative modes, driven satisfy requirements accurate flexible multimodal sensing in application scenarios.

Language: Английский

Citations

16

Fe-Capsaicin Nanozymes Attenuate Sepsis-Induced Acute Lung Injury via NF-κB Signaling DOI Creative Commons
Ruijie Wang, Quan Li,

Pengxin Wu

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 73 - 90

Published: Jan. 1, 2024

Background: In sepsis, the lungs are one of most severely affected organs, usually resulting in acute lung injury (ALI). Capsaicin (CAP) is a natural compound found chili peppers that has pain-relieving and anti-inflammatory properties. Here, we report nanoparticles containing capsaicin iron (Fe-CAP NPs) exhibited effects treatment ALI. Methods: The morphological characteristics nanozymes were detected. RAW 264.7 cells divided into four groups: control, lipopolysaccharide (LPS), CAP+LPS Fe-CAP+LPS groups. expression inducible nitric oxide synthase (iNOS), transforming growth factor-β (TGF-β), tumor necrosis factor-α (TNF-α) was assessed by immunofluorescence, Western blot, enzyme-linked immunosorbent assay (ELISA). Nuclear factor kappa-B (NF-κB) determined blot. C57 mice LPS, Interleukin-6 (IL-6) iNOS detected Blot. IL-6 TNF-α serum ELISA. Extravasated Evans blue, histopathological evaluation wet-to-dry (W/D) weight ratio used to assess pulmonary capillary permeability. blood major organs (heart, liver, spleen, kidney) tested for toxicity Fe-CAP NPs. Results: LPS group, TNF-α, iNOS, p-NF-κB p-IKBα increased. However, their significantly decreased group. TGF-β showed opposite trend. vivo, notably increased group but with pretreatment. ameliorated EB leakage, improved histopathology tissue reduced W/D ratio. non-cytotoxicity, when studying these biological activities. Conclusion: NPs could alleviated inflammation inhibiting pro-inflammatory factors macrophages, increasing factors, alleviating damage. Keywords: capsaicin, macrophage, nanoparticles,

Language: Английский

Citations

15

Two-dimensional conductive MOFs toward electrochemical sensors for environmental pollutants DOI

Mengping Liang,

Yingjie Liu, Shun Lu

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 177, P. 117800 - 117800

Published: June 7, 2024

Language: Английский

Citations

15

In-situ Nanozyme Catalytic Amplification Coupled with a Universal Antibody Orientation Strategy based Electrochemical Immunosensor for AD-Related Biomarker DOI
Xiyu Chen, Yang Huang, Shuo Yang

et al.

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 266, P. 116738 - 116738

Published: Sept. 3, 2024

Language: Английский

Citations

14

Nitrogen Vacancy Modulation of Tungsten Nitride Peroxidase-Mimetic Activity for Bacterial Infection Therapy DOI
Zhongwei Yang, Longwei Wang, Xiaoyu Zhang

et al.

ACS Nano, Journal Year: 2024, Volume and Issue: 18(35), P. 24469 - 24483

Published: Aug. 22, 2024

Bacterial infections claim millions of lives every year, with the escalating menace microbial antibiotic resistance compounding this global crisis. Nanozymes, poised as prospective substitutes for antibiotics, present a significant frontier in antibacterial therapy, yet their precise enzymatic origins remain elusive. With continuous development nanozymes, applications elemental N-modulated nanozymes have spanned multiple fields, including sensing and detection, infection cancer treatment, pollutant degradation. The introduction nitrogen into not only broadens application range but also holds importance design catalysts biomedical research. synergistic interplay between W N induces pivotal alterations electronic configurations, endowing tungsten nitride (WN) peroxidase-like functionality. Furthermore, vacancies augments nanozyme activity, thus amplifying catalytic potential WN nanostructures. Rigorous theoretical modeling empirical validation corroborate genesis enzyme activity. meticulously engineered nanoflower architecture exhibits an exceptional ability traversing bacterial surfaces, exerting potent bactericidal effects through direct physical interactions. Additionally, topological intricacies these nanostructures facilitate targeting generated radicals on culminating efficacy against both Gram-negative Gram-positive strains along notable inhibition biofilm formation. Importantly, assessments using skin model underscore proficiency nanoflowers effectively clearing fostering wound healing. This pioneering research illuminates realm pseudoenzyme activity capture-killing strategies, promising fertile ground innovative, high-performance artificial peroxidases.

Language: Английский

Citations

13

Nanozymes regulated by nitrogen element: Mechanism, design, and application DOI Creative Commons
Longhua Ding, Longwei Wang, Jian Zhang

et al.

Advanced Powder Materials, Journal Year: 2024, Volume and Issue: 3(4), P. 100191 - 100191

Published: March 18, 2024

Nanozymes, a category of nanomaterials endowed with enzyme-mimicking capabilities, have exhibited considerable potential across diverse application domains. This comprehensive review delves into the intricacies regulating nanozymes through N elements, elucidating mechanisms governing element control in design and these nanomaterials. The initial sections introduce foundational background significance nanozymes. Subsequent exploration detailed discussion regulation on nanozymes, encompassing vacancies, doping, coordination, nitride. These regulatory pathways play an instrumental role fine-tuning catalytic activity specificity further scrutinizes practical applications spanning sensing detection, infection therapy, tumor pollutant degradation. In conclusion, it succinctly summarizes current research findings proposes future directions for development. thorough investigation by elements anticipates precise over their performance, thereby advancing extensive utilization realms biomedical environmental applications.

Language: Английский

Citations

10

Semiconducting polymer dots for multifunctional integrated nanomedicine carriers DOI Creative Commons
Ze Zhang, Chenhao Yu, Yuyang Wu

et al.

Materials Today Bio, Journal Year: 2024, Volume and Issue: 26, P. 101028 - 101028

Published: March 24, 2024

The expansion applications of semiconducting polymer dots (Pdots) among optical nanomaterial field have long posed a challenge for researchers, promoting their intelligent application in multifunctional nano-imaging systems and integrated nanomedicine carriers diagnosis treatment. Despite notable progress, several inadequacies still persist the Pdots, including development simplified near-infrared (NIR) nanoprobes, elucidation inherent biological behavior, integration information processing nanotechnology into biomedical applications. This review aims to comprehensively elucidate current status Pdots as classical nanophotonic material by discussing its advantages limitations terms biocompatibility, adaptability microenvironments vivo, etc. Multifunctional surface chemistry play crucial roles realizing Pdots. Information visualization based on physicochemical properties is pivotal achieving detection, sensing, labeling probes. Therefore, we refined underlying mechanisms constructed multiple comprehensive original mechanism summaries establish benchmark. Additionally, explored cross-linking interactions between nanomedicine, potential yet complete metabolic pathways, future research directions, innovative solutions integrating treatment strategies. presents possible expectations valuable insights advancing specifically from chemical, medical, photophysical practitioners' standpoints.

Language: Английский

Citations

8