International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 137776 - 137776
Published: Nov. 1, 2024
Language: Английский
Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 25, 2025
Language: Английский
Citations
4
Materials Horizons, Journal Year: 2024, Volume and Issue: 11(18), P. 4275 - 4310
Published: Jan. 1, 2024
This comprehensive review systematically summarizes the intrinsic mechanism of different metal ion (such as Fe 3+ /Fe 2+ , Cu /Cu + Ca Zn Mn Na /K and Mg )-mediated interference therapies their research progress in cancer treatment.
Language: Английский
Citations
7
Nano Today, Journal Year: 2024, Volume and Issue: 57, P. 102386 - 102386
Published: July 13, 2024
Language: Английский
Citations
6
Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15
Published: June 27, 2024
Ferroptosis, a new type of programmed cell death proposed in recent years, is characterized mainly by reactive oxygen species and iron-mediated lipid peroxidation differs from death, such as apoptosis, necrosis, autophagy. Ferroptosis associated with variety physiological pathophysiological processes. Recent studies have shown that ferroptosis can aggravate or reduce the occurrence development diseases targeting metabolic pathways signaling tumors, ischemic organ damage, other degenerative related to peroxidation. Increasing evidence suggests closely linked onset progression various ophthalmic conditions, including corneal injury, glaucoma, age-related macular degeneration, diabetic retinopathy, retinal detachment, retinoblastoma. Our review current research on reveals significant advancements our understanding pathogenesis, aetiology, treatment these conditions.
Language: Английский
Citations
5
Biomedicine & Pharmacotherapy, Journal Year: 2025, Volume and Issue: 184, P. 117901 - 117901
Published: Feb. 11, 2025
Language: Английский
Citations
0
Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 23, 2025
Abstract Photodynamic therapy (PDT) and photothermal (PTT) offer the advantages of precise temporal spatial selectivity in cancer treatment, minimizing damage to normal cells while effectively eliminating tumor cells. However, therapeutic efficacy phototherapy is always hindered by challenges such as hypoxia heat resistance. Herein, a pH‐responsive metal‐drug nanocomplex (denoted PAFH) comprising hypericin (HYP), apigenin (APG), polyvinylpyrrolidone (PVP), Fe 3+ developed enhance PDT PTT. The PAFH exhibits properties under 808 nm laser irradiation, which can disassociate response acidic microenvironment temperature increase induced PTT, thereby eventually triggering on‐site release APG HYP. released inhibits synthesis shock protein HSP‐90, facilitating PAFH‐mediated PTT kill at mild temperature. Additionally, alleviates then regulates expression hypoxia‐inducible factor HIF‐1𝛼, increasing cellular oxygen levels produce singlet for enhanced HYP‐mediated inhibiting metastasis. Ultimately, this sophisticated nanosystem represents an advanced strategy promote mitigating counteracting resistance, significantly improving therapy.
Language: Английский
Citations
0
Chinese Medical Journal, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Nanozymes are a distinct category of nanomaterials that exhibit catalytic properties resembling those enzymes such as peroxidase (POD), superoxide dismutase (SOD), catalase (CAT), and glutathione (GPx). derived from Chinese herbal medicines the functions their enzyme mimics, while retaining specific medicinal herb (termed "herbzymes"). These nanozymes can be categorized into three main groups based on method synthesis: carbon dot nanozymes, polyphenol-metal extract nanozymes. The reported activities herbzymes include POD, SOD, CAT, GPx. This review presents an overview potential applications introduces novel concept herbzymes, provides comprehensive classification synthesis, discusses recent advances in biomedical applications. Furthermore, we also discuss significance research including primary challenges faced future development directions.
Language: Английский
Citations
0
Flavour and Fragrance Journal, Journal Year: 2025, Volume and Issue: unknown
Published: April 12, 2025
ABSTRACT Spices are substances that can be detected by the sense of smell or taste in their natural state. Currently, research on functional spices with properties such as anti‐tumour, vascularisation, anti‐inflammatory, and antibacterial effects attracts a lot attention. However, comprehensive reviews delivery systems remain limited. Among various carriers used for spice delivery, cyclodextrins widely applied due to unique properties, which feature hydrophobic interior hydrophilic exterior, particularly poorly soluble spices. In this study, representative mechanisms action introduced, then stimulus‐responsive cyclodextrin‐based summarised, applications field discussed. Furthermore, challenges faced future direction proposed promote construction an effective system.
Language: Английский
Citations
0
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 143686 - 143686
Published: April 1, 2025
Language: Английский
Citations
0
Bioactive Materials, Journal Year: 2024, Volume and Issue: 45, P. 434 - 445
Published: Dec. 3, 2024
Language: Английский
Citations
1