Fundamental Research,
Journal Year:
2023,
Volume and Issue:
5(2), P. 654 - 662
Published: April 20, 2023
Pyridylphosphonium
salts,
which
are
readily
available
and
air
thermally
stable,
have
been
used
to
effectively
synthesize
structurally
diverse
pyridines.
Herein,
we
report
the
pnictogen
bonding
(PnB)
enabled
photoactivation
of
pyridylphosphonium
salts
with
catalytic
potassium
carbonate
generate
pyridyl
radical
for
pyridine
synthesis.
Remarkably,
this
light-driven
transformation
allowed
chiral
pool
synthesis
excellent
chirality
retention,
giving
a
wide
range
selenium-containing
On
basis
our
combined
computational
experimental
studies,
propose
that
PnB
between
enables
access
photoactive
charge
transfer
complex,
is
able
undergo
single
electron
its
transformation.
Molecules,
Journal Year:
2022,
Volume and Issue:
27(11), P. 3461 - 3461
Published: May 27, 2022
Imidazopyridines
constitute
one
of
the
most
important
scaffolds
in
medicinal
chemistry,
as
their
skeleton
could
be
found
a
myriad
biologically
active
molecules.
Although
numerous
strategies
were
elaborated
for
imidazopyridine
preparation
2010s,
novel
eco-compatible
synthetic
approaches
have
emerged,
conscious
climate
change
concerns.
In
this
framework,
photochemical
methods
been
promoted
to
conceive
heterocyclic
motif
over
last
decade.
This
review
covers
recently
published
works
on
synthesizing
highly
functionalized
imidazopyridines
by
light
induction.
ACS Omega,
Journal Year:
2023,
Volume and Issue:
8(42), P. 39535 - 39545
Published: Oct. 12, 2023
Herein,
we
describe
a
urea
hydrogen
peroxide-mediated
sustainable
protocol
for
the
synthesis
of
selenylated
imidazo[2,1-b]thiazole
by
using
half
molar
equivalent
diorganyl
diselenides
in
ethyl
lactate
as
greener
solvent.
The
reaction
features
high
yields,
easy
performance
on
gram
scale,
metal-free
conditions,
well
applicability
to
imidazopyridine
and
imidazopyrimidine.
RSC Advances,
Journal Year:
2023,
Volume and Issue:
13(2), P. 914 - 925
Published: Jan. 1, 2023
Herein
we
describe
the
Ag(i)-catalyzed
direct
selanylation
of
indoles
with
diorganoyl
diselenides.
The
reaction
gave
3-selanylindoles
high
regioselectivity
and
also
allowed
access
to
2-selanylindoles
when
C3
position
indole
ring
was
blocked
Molecules,
Journal Year:
2021,
Volume and Issue:
26(15), P. 4446 - 4446
Published: July 23, 2021
Herein,
we
describe
a
simple
and
efficient
route
to
access
aniline-derived
diselenides
evaluate
their
antioxidant/GPx-mimetic
properties.
The
were
obtained
in
good
yields
via
ipso-substitution/reduction
from
the
readily
available
2-nitroaromatic
halides
(Cl,
Br,
I).
These
present
GPx-mimetic
properties,
showing
better
antioxidant
activity
than
standard
compounds,
ebselen
diphenyl
diselenide.
DFT
analysis
demonstrated
that
electronic
properties
of
substituents
determine
charge
delocalization
partial
on
selenium,
which
correlate
with
catalytic
performances.
amino
group
concurs
stabilization
selenolate
intermediate
through
hydrogen
bond
selenium.
ChemistrySelect,
Journal Year:
2024,
Volume and Issue:
9(1)
Published: Jan. 2, 2024
Abstract
A
mild
Oxone®
mediated
reaction
for
direct
regioselective
C−H
selenylation
and
thiocyanation
of
pyrazolo[1,5‐
a
]pyrimidines
is
established
at
ambient
temperature.
This
practical
efficient
methodology
employs
as
user
friendly,
green,
non‐toxic
cheap
reagent
to
facilitate
room
The
present
method
offers
high
regioselectivity,
broad
substrate
scope,
conditions
excellent
yields.
Further,
this
eco‐friendly
approach
could
easily
be
extended
other
heterocycles.
Mechanistic
studies
indicate
that
the
occurs
through
electrophilic
substitution
mechanism
via
generation
an
chalcogen
species.
Scientific Reports,
Journal Year:
2023,
Volume and Issue:
13(1)
Published: Aug. 31, 2023
In
this
paper,
we
report
an
eco-friendly
approach
for
the
C(sp2)-H
bond
selenylation
of
imidazopyridines
and
other
N-heteroarenes
as
well
simple
arenes
at
ambient
temperature.
This
new
protocol
consists
reaction
between
(N-hetero)-arenes
diorganyl-diselenides
trichloroisocyanuric
acid
(TCCA)-ethanol
reagent
system.
a
short
time,
desired
selenylated
products
were
obtained
regioselectively
in
good
yields,
with
tolerance
wide
range
functional
groups.
Catalysts,
Journal Year:
2023,
Volume and Issue:
13(3), P. 520 - 520
Published: March 3, 2023
This
review
describes
the
recent
advances
in
photocatalyzed
reactions
to
form
new
carbon–sulfur
and
carbon–selenium
bonds.
With
a
total
of
136
references,
which
81
articles
are
presented,
authors
introduce
five
sections
an
updated
picture
state
art
light-promoted
synthesis
organochalcogen
compounds
(from
2019
present).
The
sulfides
by
direct
sulfenylation
C–C
π-bonds;
sulfones;
activation
Csp2–N
bond
formation
Csp2–S
bonds;
thiol
ester,
thioether
thioacetal;
organoselenium
discussed,
with
detailed
reaction
conditions
selected
examples
for
each
protocol.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(18), P. 6614 - 6614
Published: Sept. 14, 2023
The
importance
of
organoselenium
compounds
has
been
increasing
in
synthetic
chemistry.
These
reagents
are
well-known
as
electrophiles
and
nucleophiles
many
organic
transformations,
recent
years,
their
functionality
catalysts
also
largely
explored.
interest
organoselenium-based
is
due
to
high
efficacy,
mild
reaction
conditions,
strong
functional
compatibility,
great
selectivity.
Allied
catalysts,
the
use
inorganic
oxidants
that
act
by
regenerating
catalytic
species
for
pathway
common.
Here,
we
provide
a
comprehensive
review
last
five
years
transformations
promoted
diorganyl
diselenide
selenium-based
catalyst.
This
report
divided
into
four
sections:
(1)
cyclisation
reactions,
(2)
addition
reactions
oxidative
functionalisation,
(3)
oxidation
reduction
(4)
involving
phosphorus-containing
starting
materials.
In
this
report,
we
disclose
an
electrochemical
approach
for
the
C(sp2)-H
chalcogenation
of
pyrazolo[1,5-a]pyrimidines
at
room
temperature
via
radical
cross-coupling
reaction.
The
reaction
takes
place
within
undivided
cell
employing
graphite
electrodes,
with
TBABF4
acting
as
supporting
electrolyte.
This
technique
offers
a
rapid,
oxidant-free,
and
environmentally
conscious
protocol
achieving
regioselective
specifically
C3
position
pyrazolo[1,5-a]pyrimidines.
Furthermore,
procedure
uses
only
0.5
equivalents
diaryl
chalcogenides
which
underscores
atom
economy
protocol.
Key
attributes
methodology
include
mild
conditions,
short
time,
utilization
cost-effective
electrode
materials,
reliable
achievement
yields
ranging
from
good
to
excellent
friendly
conditions.
Cyclic
voltammetry
studies
quenching
experiments
suggest
pathway
mechanism.
