Recent advances in stimuli-responsive tailored nanogels for cancer therapy; from bench to personalized treatment DOI

Prinsy Rana,

Charan Singh, Ajeet Kaushik

et al.

Journal of Materials Chemistry B, Journal Year: 2023, Volume and Issue: 12(2), P. 382 - 412

Published: Dec. 14, 2023

To improve the quality of health in a personalized manner, better control over pharmacologically relevant cargo formulation, organ-specific targeted delivery, and on-demand release therapeutic agents is crucial. Significant work has been put into designing developing revolutionary nanotherapeutics approaches for effective monitoring treatment disease. Nanogel (NG) attracted significant interest because its tremendous potential cancer therapy environmental stimuli responsiveness. NG considered next-generation delivery technology due to benefits like as size tunability, high loading, responsiveness, prolonged drug

Language: Английский

Advances in Polysaccharide-Based Microneedle Systems for the Treatment of Ocular Diseases DOI Creative Commons

Qingdong Bao,

Xiaoting Zhang,

Zhankun Hao

et al.

Nano-Micro Letters, Journal Year: 2024, Volume and Issue: 16(1)

Published: Aug. 13, 2024

Abstract The eye, a complex organ isolated from the systemic circulation, presents significant drug delivery challenges owing to its protective mechanisms, such as blood-retinal barrier and corneal impermeability. Conventional administration methods often fail sustain therapeutic levels may compromise patient safety compliance. Polysaccharide-based microneedles (PSMNs) have emerged transformative solution for ophthalmic delivery. However, comprehensive review of PSMNs in ophthalmology has not been published date. In this review, we critically examine synergy between polysaccharide chemistry microneedle technology enhancing ocular We provide thorough analysis PSMNs, summarizing design principles, fabrication processes, addressed during fabrication, including improving comfort also describe recent advances performance various both research clinical scenarios. Finally, current regulatory frameworks market barriers that are relevant commercial advancement final perspective on area.

Language: Английский

Citations

8
Recent advances in stimuli-responsive tailored nanogels for cancer therapy; from bench to personalized treatment DOI

Prinsy Rana,

Charan Singh, Ajeet Kaushik

et al.

Journal of Materials Chemistry B, Journal Year: 2023, Volume and Issue: 12(2), P. 382 - 412

Published: Dec. 14, 2023

To improve the quality of health in a personalized manner, better control over pharmacologically relevant cargo formulation, organ-specific targeted delivery, and on-demand release therapeutic agents is crucial. Significant work has been put into designing developing revolutionary nanotherapeutics approaches for effective monitoring treatment disease. Nanogel (NG) attracted significant interest because its tremendous potential cancer therapy environmental stimuli responsiveness. NG considered next-generation delivery technology due to benefits like as size tunability, high loading, responsiveness, prolonged drug

Language: Английский

Citations

4