Journal of Biomedical Materials Research Part B Applied Biomaterials,
Journal Year:
2025,
Volume and Issue:
113(5)
Published: May 1, 2025
ABSTRACT
Carrageenan
(CGN)
is
a
high
molecular
weight
polysaccharide
that
extracted
from
red
seaweeds.
It
made
up
of
D‐galactose
residues
connected
by
β‐1,4
and
α‐1,3
galactose‐galactose
bonds.
As
result
its
ability
to
thicken,
emulsify,
stabilize
food,
it
frequently
used
as
food
additive
in
processed
food.
Its
consumption
has
surged
recent
years
due
the
Western
diet's
(WD)
spread.
change
thickness
mucus
barrier,
composition
gut
microbiota,
innate
immune
pathway
causes
inflammation.
Also,
inherent
qualities,
which
include
biodegradability,
biocompatibility,
resemblance
native
glycosaminoglycans,
antioxidants,
anticancer,
immunomodulatory,
anticoagulant
activities,
Carrageenan‐based
hydrogels
have
been
subject
numerous
investigations
lately
for
biomedical
applications.
The
brittle
hydrogel
uncontrollably
exchanged
ions,
however,
are
two
drawbacks
application
this
polysaccharide,
but
these
can
be
avoided
making
straightforward
chemical
changes
polymer
networks,
create
chemically
bonded
with
important
mechanical
characteristics
regulated
degradation
rates.
Furthermore,
addition
diverse
kinds
nanoparticles,
well
carrageenan
results
hybrid
platforms
noteworthy
mechanical,
chemical,
biological
characteristics,
qualify
them
appropriate
biomaterials
tissue
engineering
(TE),
drug
delivery
(DD),
also
wound
healing
Our
goal
article
provide
an
overview
most
current
developments
carrageenan‐based
several
modification
techniques
TE
DD
Ultrasonics Sonochemistry,
Journal Year:
2025,
Volume and Issue:
114, P. 107259 - 107259
Published: Feb. 7, 2025
This
study
investigates
two
extraction
methods-ultrasound-assisted
(UAE)
and
compound
enzyme
(CE)-for
the
isolation
of
Lonicera
macranthoides
polysaccharides
(LMP)
evaluates
their
physicochemical
properties,
bioactivity,
therapeutic
potential.
The
optimization
conditions
was
performed
using
single-factor
experiments
response
surface
methodology.
yield
LMP
from
UAE
optimized
to
8.02
%
±
0.12
%,
while
CE
10.03
0.32
%.
Both
polysaccharide
extracts
were
characterized
in
terms
chemical
composition,
monosaccharide
molecular
weight,
thermal
stability,
functional
group
analysis.
Notably,
UAE-LMP
exhibited
superior
antioxidant,
hypolipidemic,
nitrite
scavenging,
anti-tumor
activities
compared
CE-LMP.
ultrasound-assisted
method
enhanced
stability
bioactivity
LMP,
with
improved
water-
oil-holding
capacities
integrity
active
groups.
Our
findings
demonstrate
that
significantly
influences
structural
properties
suggesting
may
be
a
more
effective
approach
for
extracting
bioactive
potential
applications
medicine
nutrition.