Cannabis and Cannabinoid Research,
Journal Year:
2020,
Volume and Issue:
7(1), P. 107 - 115
Published: Sept. 10, 2020
Background:
Recently
increased
access
to
cannabis
products
in
the
United
States
has
been
associated
with
rates
of
driving
after
use.
Although
numerous
studies
indicate
that
impairs
psychomotor
and
neurocognitive
functions
can
affect
ability,
determination
cannabis-impaired
risk
is
complicated
by
extent
which
frequent
users
develop
tolerance
THC's
subjective,
cognitive,
effects,
fact
there
no
validated
behavioral
or
biological
marker
recent
use
cannabis-related
impairment.
This
study
examined
impairment-related
effects
experienced
Colorado
naturalistic
consumption
smoked
cannabis,
both
immediately
1
h
postuse.
Results
were
then
a
smaller
replication
sample
from
Washington
state.
Methods:
In
primary
study,
participants
(n=70)
used
DRUID®
mobile
app,
brief
measure
cognitive
domains
are
sensitive
cannabis.
First,
DRUID
establish
sober
baseline
impairment
score.
During
second
appointment,
they
at
three
time
points:
preuse,
acutely
using
sample,
(n=39)
before
acute
every
half
hour
for
2.5
h.
Results:
studies,
peak
seen
use,
recovery
performance
Specifically,
significant
quadratic
emerged
(Colorado
study:
(β=−0.935,
SE=0.204,
p<0.001);
β=3.0299,
SE=1.3085,
p<0.01).
Domain-specific
tested
larger
observed
reaction
within
complex
divided
attention
task
postural-stability
balance
task.
Conclusions:
These
findings
demonstrate
emerges
even
regular
users,
but
decreases
significantly
results
underscore
potential
utility
app
assessing
Further
research
needed
explore
whether
and/or
specific
it
assesses
might
serve
as
tool
measuring
Clinical
trials
registration
number
Study:
NCT03522103.
JAMA Psychiatry,
Journal Year:
2019,
Volume and Issue:
77(2), P. 165 - 165
Published: Nov. 13, 2019
Little
is
known
about
changes
in
marijuana
use
and
cannabis
disorder
(CUD)
after
recreational
legalization
(RML).To
examine
the
associations
between
RML
enactment
use,
frequent
CUD
United
States
from
2008
to
2016.This
survey
study
used
repeated
cross-sectional
data
National
Survey
on
Drug
Use
Health
(2008-2016)
conducted
among
participants
age
groups
of
12
17,
18
25,
26
years
or
older.Multilevel
logistic
regression
models
were
fit
obtain
estimates
before-vs-after
respondents
states
enacting
compared
other
states.Self-reported
past-month
users,
past-year
CUD,
users.The
included
505
796
consisting
51.51%
females
77.24%
older.
Among
total,
65.43%
white,
11.90%
black,
15.36%
Hispanic,
7.31%
race/ethnicity.
aged
17
years,
increased
2.18%
2.72%
enactment,
a
25%
higher
increase
than
that
for
same
group
did
not
enact
(odds
ratio
[OR],
1.25;
95%
CI,
1.01-1.55).
users
this
group,
22.80%
27.20%
(OR,
1.27;
1.01-1.59).
Unmeasured
confounders
would
need
be
more
prevalent
risk
by
1.08
1.11
times
explain
observed
results,
indicating
results
are
sensitive
omitted
variables.
No
found
25
years.
older,
5.65%
7.10%
1.28;
1.16-1.40),
2.13%
2.62%
1.24;
1.08-1.41),
0.90%
1.23%
1.36;
1.08-1.71);
these
robust
unmeasured
confounding.
enactment.This
study's
findings
suggest
although
advanced
social
justice
goals,
small
post-RML
adults
older
potential
public
health
concern.
To
undertake
prevention
efforts,
further
studies
warranted
assess
how
increases
occur
identify
subpopulations
may
especially
vulnerable.
The American Journal of Drug and Alcohol Abuse,
Journal Year:
2019,
Volume and Issue:
45(6), P. 644 - 663
Published: Oct. 11, 2019
Background:
The
past
decade
has
seen
unprecedented
shifts
in
the
cannabis
policy
environment,
and
public
health
impacts
of
these
changes
will
hinge
on
how
they
affect
patterns
use
harms
associated
with
other
substances.Objectives:
To
review
existing
research
state
substance
use,
emphasizing
studies
using
methods
for
causal
inference
highlighting
gaps
our
understanding
evolving
markets.Methods:
Narrative
quasi-experimental
medical
laws
(MCLs)
recreational
(RCLs)
disorders,
as
well
or
from
alcohol,
opioids,
tobacco.Results:
Research
suggests
MCLs
increase
adult
but
not
adolescent
provisions
less
regulated
supply
may
disorders.
These
reduce
some
opioid-related
harms,
while
their
alcohol
tobacco
remain
uncertain.
RCLs
is
just
emerging,
findings
suggest
little
impact
prevalence
potential
increases
college
student
unknown
effects
use.Conclusions:
influence
advanced
importance
heterogeneity
policies,
populations,
market
dynamics,
relate
to
often
ignore
factors.
Understanding
requires
greater
attention
differences
short-
versus
long-term
laws,
nuances
policies
consumption,
careful
consideration
appropriate
control
groups.
BMJ Open,
Journal Year:
2019,
Volume and Issue:
9(7), P. e025880 - e025880
Published: July 1, 2019
Objectives
To
examine
the
effect
of
cannabis
policy
liberalisation
(decriminalisation
and
legalisation)
levels
use
in
adolescents
young
adults.
Design
Systematic
review
meta-analysis.
Inclusion
criteria
Included
studies
were
conducted
among
individuals
younger
than
25
years
quantitatively
assessing
consequences
change.
We
excluded
articles:
(A)
exclusively
based
on
participants
older
years;
(B)
only
reporting
changes
perceptions
use;
(C)
not
including
at
least
two
measures
(D)
quantitative
data;
(E)
reviews,
letters,
opinions
papers.
PubMed,
PsycINFO,
Embase
Web
Science
searched
through
1
March
2018.
Data
extraction
synthesis
Two
independent
readers
reviewed
eligibility
titles
abstracts
read
eligible
articles,
four
authors
assessed
risk
bias
(Quality
Assessment
Tool
for
Observational
Cohort
Cross-Sectional
Studies).
Extracted
data
meta-analysed.
The
protocol
was
registered
with
PROSPERO.
Results
3438
records
identified
via
search
terms
citation
lists;
2312
retained
after
removal
duplicates,
99
41
included
our
systematic
review.
13
articles
examined
decriminalisation,
20
legalisation
medical
purposes
8
recreational
purposes.
Findings
regarding
decriminalisation
or
too
heterogeneous
to
be
Our
meta-analysis
suggest
a
small
increase
adults
following
(standardised
mean
difference
0.03,
95%
CI
−0.01
–0.07).
Nevertheless,
characterised
by
very
low/low
showed
no
evidence
modifications.
Conclusions
Cannabis
does
appear
result
significant
youths’
use,
possible
exception
that
requires
monitoring.
Trial
registration
number
CRD42018083950.
Frontiers in Public Health,
Journal Year:
2024,
Volume and Issue:
11
Published: Jan. 5, 2024
Background
There
are
well-established
literatures
documenting
the
associations
between
mental
disorders
and
unhealthy
behaviors
such
as
poor
diet
quality,
sedentary
behavior,
cannabis
tobacco
use.
Few
studies
have
attempted
to
understand
respective
findings
in
light
of
each
other,
however.
Objective
The
purpose
this
review
was
assemble
comparable
data
for
behavior-disorder
association
assess
terms
their
overall
strength.
aimed
include
a
representative,
but
not
exhaustive,
range
that
would
allow
explorative
comparisons.
Methods
Eligible
were
identified
via
Pubmed
searches
citation
searching,
restricted
publications
no
older
than
2015
written
English.
To
obtain
data,
only
reported
odds
ratios
included,
risk
bias
related
study
samples,
behavioral
measurement
disparities,
control
variables
assessed
sensitivity
analyses.
Findings
disorder
compared
on
basis
different
measures
central
tendency.
Results
From
3,682
records,
294
included.
found
evidence
four
psychosis,
depression,
anxiety,
bipolar
disorder,
attention-deficit/hyperactivity
(ADHD),
post-traumatic
stress
(PTSD),
while
personality
investigated
relation
In
comparison,
generally
similar
strength,
use
exceptional
being
significantly
stronger
its
counterparts
across
behaviors.
Analyses
some
influence
from
disparities
lack
adequate
statistical
control,
robust
Conclusion
This
comparative
about
equally
strongly
associated
with
disorders.
Given
general
nature
these
associations,
we
should
probably
them
reflect
shared
etiology.
However,
be
regarded
tentative
until
confirmed
by
more
comprehensive
investigations.