Nutrients,
Journal Year:
2023,
Volume and Issue:
15(13), P. 2994 - 2994
Published: June 30, 2023
Binge-eating
disorder
(BED)
is
a
highly
prevalent
disorder.
Subthreshold
BED
conditions
(sBED)
are
even
more
frequent
in
youth,
but
their
significance
regarding
etiology
and
long-term
prognosis
unclear.
A
better
understanding
of
brain
findings
associated
with
sBED,
the
context
critical
periods
for
neurodevelopment,
relevant
to
answer
such
questions.
The
present
narrative
review
starts
from
knowledge
development
emotional
self-regulation
circuits
supporting
emotion-regulation
eating
behaviour.
Next,
neuroimaging
studies
sBED
samples
will
be
reviewed,
brain-circuitry
overlap
examined.
Deficits
inhibition
control
systems
observed
precede,
hyperactivity
reward
regions
characterize,
overlapping
BED.
imbalance
between
reward/inhibition
systems,
implication
interoception/homeostatic
processing
should
further
Recent
potential
impact
that
high
consumption
ultra-processed
foods
paediatric
may
have
on
these
sBED/BED-associated
then
discussed.
There
need
identify,
early
on,
those
individuals
at
risk
developing
neurodevelopmental
stages
when
there
great
possibility
prevention.
However,
sBED/BED
pediatric
needed.
Comprehensive Reviews in Food Science and Food Safety,
Journal Year:
2024,
Volume and Issue:
23(2)
Published: March 1, 2024
Abstract
The
food
industry
has
been
extremely
successful
in
creating
a
broad
range
of
delicious,
affordable,
convenient,
and
safe
beverage
products.
However,
many
these
products
are
considered
to
be
ultraprocessed
foods
(UPFs)
that
contain
ingredients
processed
manner
may
cause
adverse
health
effects.
This
review
article
introduces
the
concept
UPFs
briefly
discusses
fall
into
this
category,
including
beverages,
baked
goods,
snacks,
confectionary,
prepared
meals,
dressings,
sauces,
spreads,
meat
analogs.
It
then
correlations
between
consumption
levels
diet‐related
chronic
diseases,
such
as
obesity
diabetes.
different
reasons
for
proposed
ability
increase
risk
diseases
critically
assessed,
displacement
whole
foods,
high
energy
densities,
missing
phytochemicals,
contamination
with
packaging
chemicals,
hyperpalatability,
harmful
additives,
rapid
ingestion
digestion,
toxic
reaction
Then,
potential
strategies
overcome
current
problems
presented,
reducing
density,
balancing
nutritional
profile,
fortification,
increasing
satiety
response,
modulating
mastication
reengineering
structure,
precision
processing.
central
argument
is
it
possible
reformulate
reengineer
improve
their
healthiness
sustainability,
although
still
needs
proved
using
rigorous
scientific
studies.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(3), P. 504 - 504
Published: Jan. 18, 2023
Excess
consumption
of
ultra-processed
foods
(UPFs)
is
currently
under
investigation
for
its
potentially
detrimental
impact
on
human
health.
Current
evidence
demonstrates
a
substantial
association
with
an
increased
risk
metabolic
disorders,
but
data
mental
health
outcomes
are
just
emerging.
The
aim
this
study
was
to
investigate
the
relationship
between
UPFs
and
depressive
symptoms
in
sample
younger
Italian
adults.
A
cross-sectional
conducted
596
individuals
(age
18-35
y)
recruited
southern
Italy.
Food
frequency
questionnaires
NOVA
classification
were
used
assess
dietary
factors;
Center
Epidemiological
Studies
Depression
Short
Form
(CES-D-10)
presence
symptoms.
Individuals
highest
quartile
UPF
had
higher
odds
having
energy-adjusted
model
(odds
ratio
(OR)
=
1.89,
95%
confidence
interval
(CI):
1.06,
3.28);
remained
significant
after
adjusting
potential
confounding
factors
(OR
2.04,
CI:
1.04,
4.01)
became
even
stronger
further
adjustment
adherence
Mediterranean
diet
as
proxy
quality
2.70,
1.32,
5.51).
In
conclusion,
positive
likelihood
found
individuals.
Given
consistency
findings
quality,
studies
needed
understand
whether
non-nutritional
may
play
role
neurobiology.
Journal of Affective Disorders,
Journal Year:
2023,
Volume and Issue:
335, P. 340 - 348
Published: May 18, 2023
The
consumption
of
ultra-processed
foods
and
drinks
(UPF)
has
been
associated
with
depression
inflammation
preclinical
studies
showed
that
some
UPF
components
disrupt
the
amygdala-hippocampal
complex.
We
combine
diet,
clinical
brain
imaging
data
to
investigate
relationship
between
consumption,
depressive
symptoms,
volumes
in
humans,
considering
interactions
obesity,
mediation
effect
biomarkers.One-hundred
fifty-two
adults
underwent
anatomic
magnetic
resonance
assessments
laboratory
tests.
Relationships
%
(in
grams)
total
gray
matter
were
explored
using
several
adjusted
regression
models,
interaction
presence
obesity.
Whether
inflammatory
biomarkers
(i.e.,
white
blood
cell
count,
lipopolysaccharide-binding
protein,
c-reactive
protein)
mediate
previous
associations
was
investigated
R
package.High
higher
symptoms
all
participants
(β
=
0.178,
CI
0.008-0.261)
those
obesity
0.214,
-0.004-0.333).
Higher
also
lower
posterior
cingulate
cortex
left
amygdala,
which
encompassed
ventral
putamen
dorsal
frontal
cortex.
White
count
levels
mediated
association
(p
0.022).The
present
study
precludes
any
causal
conclusions.UPF
is
within
mesocorticolimbic
network
implicated
reward
processes
conflict
monitoring.
Associations
partially
dependent
on
count.
Antioxidants,
Journal Year:
2023,
Volume and Issue:
12(8), P. 1532 - 1532
Published: July 31, 2023
In
the
last
few
decades
consumption
of
ultra-processed
foods
(UPFs)
worldwide
has
substantially
augmented.
Increasing
evidence
suggests
that
high
UPF
is
associated
with
an
increase
in
non-communicable
diseases,
being
overweight,
and
obesity.
The
aim
this
study
was
to
assess
how
affects
oxidative
inflammatory
status
plasma,
neutrophils,
urine
old
adults
metabolic
syndrome.
Participants
(n
=
92)
were
classified
into
two
groups
according
consumption.
Dietary
intakes
measured
by
a
validated
semi-quantitative
143-item
food
frequency
questionnaire
determined
NOVA
classification
system.
Low
consumers
showed
higher
adherence
Mediterranean
diet
than
consumers.
A
intake
fiber
concentration
polyphenols
also
observed
subjects
low
Despite
absence
differences
biochemical
profile,
biomarkers
some
significant
changes.
Catalase
superoxide
dismutase
activities
lower
consumers,
whereas
myeloperoxidase
activity
higher.
ROS
production
neutrophils
stimulated
zymosan
Biomarkers
such
as
xanthine
oxidase,
tumor
necrosis
factor
α
(TNFα),
interleukin
(IL)-6,
IL-15,
leptin
levels
participants
UPF.
No
found
malondialdehyde
other
cytokines.
current
evidenced
MetS
have
more
pro-oxidant
profile
those
consumption,
despite
showing
similar
blood
profiles.
Philosophical Transactions of the Royal Society B Biological Sciences,
Journal Year:
2023,
Volume and Issue:
378(1888)
Published: Sept. 4, 2023
Absolute
energy
from
fats
and
carbohydrates
the
proportion
of
in
food
supply
have
increased
over
50
years.
Dietary
density
(ED)
is
primarily
decreased
by
water
fat
content
foods.
Protein,
exert
different
effects
on
satiety
or
intake
(EI)
order
protein
>
fat.
When
ED
foods
equalized
differences
between
are
modest.
Covertly
increasing
dietary
with
fat,
carbohydrate
mixed
macronutrients
elevates
EI,
producing
weight
gain
vice
versa.
In
more
naturalistic
situations
where
learning
cues
intact,
there
appears
to
be
greater
compensation
for
There
considerable
individual
variability
response.
Macronutrient-specific
negative
feedback
models
EI
regulation
limited
capacity
explain
how
availability
cheap,
highly
palatable,
readily
assimilated,
energy-dense
lead
obesity
modern
environments.
Neuropsychological
constructs
including
reward
(liking,
wanting
learning),
reactive
reflective
decision
making,
context
asymmetric
balance
regulation,
give
comprehensive
explanations
environmental
superabundance
containing
mixtures
assimilated
caloric
beverages
elevate
through
combined
hedonic,
affective,
cognitive
physiological
mechanisms.
This
article
part
a
discussion
meeting
issue
'Causes
obesity:
theories,
conjectures
evidence
(Part
II)'.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(12), P. 1955 - 1955
Published: June 19, 2024
Ultra-processed
foods
(UPFs)
like
pastries,
packaged
snacks,
fast
foods,
and
sweetened
beverages
have
become
dominant
in
the
modern
food
supply
are
strongly
associated
with
numerous
public
health
concerns.
While
physical
consequences
of
UPF
intake
been
well
documented
(e.g.,
increased
risks
cardiometabolic
conditions),
less
empirical
discussion
has
emphasized
mental
chronic
consumption.
Notably,
unique
characteristics
UPFs
artificially
high
levels
reinforcing
ingredients)
influence
biological
processes
dopamine
signaling)
a
manner
that
may
contribute
to
poorer
psychological
functioning
for
some
individuals.
Importantly,
gold-standard
behavioral
lifestyle
interventions
treatments
specifically
disordered
eating
do
not
acknowledge
direct
role
play
sensitizing
reward-related
neural
functioning,
disrupting
metabolic
responses,
motivating
subsequent
cravings
intake.
The
lack
consideration
influences
on
is
particularly
problematic
given
growing
scientific
support
addictive
properties
these
utility
ultra-processed
addiction
(UPFA)
as
novel
clinical
phenotype
endorsed
by
14–20%
individuals
across
international
samples.
overarching
aim
present
review
summarize
science
how
affect
health,
emphasizing
contributing
mechanisms.
Specifically,
authors
will
(1)
describe
corporate-sponsored
research
financial
agendas
contributed
contention
debate
about
health;
(2)
define
their
nutritional
characteristics;
(3)
observed
associations
between
conditions,
especially
depression;
(4)
outline
evidence
UPFA;
(5)
nuanced
treatment
considerations
comorbid
UPFA
disorders.
Dietetics,
Journal Year:
2024,
Volume and Issue:
3(2), P. 144 - 158
Published: May 7, 2024
Obesity
is
considered
an
important
risk
factor
for
the
onset
of
asthma,
playing
a
key
role
in
enhancing
disease’s
severity.
However,
there
increasing
evidence
linking
not
only
obesity
but
also
overweight
with
higher
asthma.
Although
correlation
between
and
asthma
has
already
been
reported,
several
aspects
are
still
fully
elucidated,
mainly
about
inflammatory
processes
underlying
both
diseases.
It
well
known
that
Western-type
calorically
rich
diets
overfeeding
can
act
as
triggers
chronic
metabolic
inflammation,
few
studies
have
examined
associations
ultra-processed
foods
(UPFs)
intake,
despite
its
positive
obesity,
biomarkers
inflammation.
In
addition
to
their
nutrient
composition,
UPF
may
chemical
additives
contaminants
from
packaging,
whose
effects
on
health
food
addiction
under
research.
this
review,
we
provide
overview
current
data
identify
obese
phenotype
consumption,
highlighting
potential
central
played
by
intestinal
microbiota.
Current Addiction Reports,
Journal Year:
2022,
Volume and Issue:
9(4), P. 255 - 267
Published: May 2, 2022
Abstract
Purpose
of
Review
To
examine
the
prevalence
rates
ultra-processed
food
addiction
across
different
weight
classes
and
offer
guidelines
for
diagnosis
treatment.
Clinicians
are
provided
with
practical
considerations
in
assessment
beyond
use
validated
instruments.
Recent
Findings
The
weighted
mean
is
approximately
20%
worldwide
varies
widely
based
on
sample.
At
first
glance,
there
appears
a
linear
relationship
between
BMI
class.
Further
investigation
indicates
J-shaped
curve
heightened
among
underweight.
These
findings
highlight
need
to
assess
additional
factors
that
may
increase
objective
or
subjective
symptoms
including
eating
disorders,
dietary
restraint,
other
mental
health
diagnoses.
Summary
While
clinical
vary,
overemphasis
status
detract
from
utility
construct.
Considering
conjunction
psychiatric
helps
better
understand
various
biopsychosocial
mechanisms
influence
behavior
can
inform
individualized
treatment
strategies.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(20), P. 3524 - 3524
Published: Oct. 17, 2024
Background/Objectives:
We
investigated
the
effects
of
ultraprocessed
food
(UPF)
consumption
on
metabolic
disorders
(e.g.,
adiposity,
associated
steatotic
liver
disease
[MASLD],
and
insulin
resistance)
in
children
adolescents
with
obesity
to
improve
dietary
guidelines
public
health
strategies.
Methods:
The
intake
149
participants
(aged
8–17
years)
was
assessed
diaries.
NOVA
classification
system
used
classify
according
degree
processing.
Metabolic
outcomes,
including
fat
mass
index
(FMI),
hepatic
percentage,
resistance,
were
measured
via
dual-energy
X-ray
absorptiometry
(DXA),
magnetic
resonance
imaging
proton
density
fraction
(MRI-PDFF),
biochemical
analysis,
respectively.
Results:
Greater
UPF
from
baseline
6-month
follow-up
significantly
increased
decreased
total
cholesterol
LDL-cholesterol.
positively
prevalence
MASLD
(liver
MRI-PDFF
≥
5%;
odds
ratio
T3
vs.
T1
=
1.75;
95%
confidence
interval
[CI]
1.03,
3.00),
moderate-to-severe
10%;
OR
4.19;
CI
1.72,
10.22),
resistance
(OR
2.44;
1.33,
4.48),
after
adjusting
for
covariates.
A
linear
dose-response
relationship
observed
between
resistance.
Conclusions:
strongly
obesity,
underscoring
importance
reducing
through
interventions
mitigate
risk
obesity-related
conditions
young
populations.
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(1), P. 174 - 174
Published: Jan. 2, 2025
Background:
It
is
common
for
consumers
to
purchase
ultra-processed
foods
that
are
perceived
have
health
risks,
and
this
phenomenon
rarely
explained
in
the
existing
literature
from
perspective
of
consumers’
responses
intuitive
marketing
flavor
labels
packaging.
Methods:
This
study
aimed
fill
knowledge
gap
investigated
attention
920
participants
aged
18~59
across
China
toward
fat
sodium
content
information
six
(pastry
foods,
quick-frozen
dessert
puffed
beverages,
sauces)
presented
nutrition
facts
tables
based
on
theoretical
analysis
framework
purchasing
decisions
by
using
binary
logit
model.
Results:
was
found
respondent’
s
positively
influenced
risk
perception
levels
about
but
negatively
interaction
term
between
(or
packaging)
stimulated
desire
sodium).
Conclusions:
The
stimulation
packaging
weakened
consumer’
increased
being
enhanced
level
sodium,
especially
probability
such
sauces,
which
dropped
most.
Additionally,
females,
youth,
low-income
individuals,
those
with
below-college
education,
non-overweight
obese
individuals
more,
decrease
largest
sauces.