Potential Causes of Spread of Antimicrobial Resistance and Preventive Measures in One Health Perspective-A Review

Infection and Drug Resistance, Journal Year: 2023, Volume and Issue: Volume 16, P. 7515 - 7545

Published: Dec. 1, 2023

Abstract: Antimicrobial resistance, referring to microorganisms' capability subsist and proliferate even when there are antimicrobials is a foremost threat public health globally. The appearance of antimicrobial resistance can be ascribed anthropological, animal, environmental factors. Human-related causes include overuse misuse in medicine, antibiotic-containing cosmetics biocides utilization, inadequate sanitation hygiene settings. Prophylactic therapeutic overuse, using as feed additives, microbes resistant antibiotics genes animal excreta, residue found animal-origin food excreta animals related contributive factors for the antibiotic emergence spread. Environmental including naturally existing genes, improper disposal unused antimicrobials, contamination from waste settings, farms, pharmaceutical industries, use agricultural chemicals facilitatet its Wildlife has plausible role Adopting one-health approach involving properly humans, improving spaces implementing coordinated governmental regulations crucial combating resistance. Collaborative cooperative involvement stakeholders public, veterinary ecological sectors circumvent problem effectively. Keywords: one health, gene, environment, wildlife

Language: Английский

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Global trends in the research and development of medical/pharmaceutical wastewater treatment over the half-century

Chemosphere, Journal Year: 2023, Volume and Issue: 331, P. 138775 - 138775

Published: April 24, 2023

Language: Английский

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Synthesis, characterization, and applications of ambi-functional PANI/GO/MOF-Fe3O4 magnetic nanocomposite for removing industrial dye and emerging contaminant

Separation and Purification Technology, Journal Year: 2024, Volume and Issue: 351, P. 128052 - 128052

Published: May 22, 2024

Language: Английский

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Occurrence of selected pharmaceuticals in wastewater and sludge samples from wastewater treatment plants in Eastern Cape province of South Africa

South African Journal of Chemistry, Journal Year: 2024, Volume and Issue: 78, P. 7 - 14

Published: Jan. 1, 2024

ABSTRACT The occurrence of pharmaceuticals in various wastewater treatment plants (WWTPs) and their discharge into the surface water are existing global challenges. However, such challenges more detrimental developing countries due to aging infrastructure its vandalism influenced by poverty, resulting illegal breakdown WWTPs. This study investigated presence efavirenz, ibuprofen, naproxen, sulfamethoxazole, trimethoprim Ultrasound-assisted extraction (UAE) followed solid-phase (SPE) was used extract these sludge samples, with extracted only latter. analysis using a high-performance liquid chromatography-photo-diode array detection system. Recoveries found after spiking samples analytes at different concentrations ranged from 56 117%. An antibiotic, among prominent drugs untreated concentration reaching 77 ug L-1. All were detected naproxen having highest 13.35 ng g-1. pharmaceutical lowest removal efficiency (2-12%) WWTPs while other fairly removed wastewater. Overall, findings this indicate dysfunctionality selected Eastern Cape province South Africa release high amounts which can be humans, animals, aquatic life.

Language: Английский

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Occurrence of emerging contaminants in three river basins impacted by wastewater treatment plant effluents: Spatio-seasonal patterns and environmental risk assessment

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 946, P. 174062 - 174062

Published: June 24, 2024

The concern on the fate and distribution of contaminants emerging (CECs) is a burning topic due to their persistence potential harmful effects. Particularly, antibiotics have received great attention implications in antimicrobial resistance occurrence. impact wastewater treatment plants (WWTP) remarkable, being one main pathways for introduction CECs into aquatic systems. combination novel analytical methodologies risk assessment strategies promising tool find out environmentally relevant compounds posing major concerns freshwater ecosystems impacted by those effluents. Within this context, multi-target approach was applied three Spanish river basins affected different WWTP treated effluents spatio-temporal monitoring chemical status. Solid phase extraction followed ultra-high-performance liquid chromatography were used quantification large panel (n = 270), including pharmaceuticals other consumer products, pesticides industrial chemicals. To end, water samples collected four sampling campaigns at locations each basin: (i) upstream from WWTPs; (ii) effluent discharge points (effluent outfall); (iii) downstream WWTPs (500 m downriver outfall). Likewise, 24-h composite provided all periods. First occurrence these assessed. Diverse seasonal trends observed depending group compounds, though COVID-19 outbreak variations certain pharmaceuticals. Detection frequencies concentrations generally exceeded measured low or non-quantifiable. Finally, risks associated with maximum contamination levels evaluated using two approaches account antibiotic selection as well. From studied 89 evidenced environmental least occasion study.

Language: Английский

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Catalytic insights into laccase for sustainable remediation of multifaceted pharmaceutically active micropollutants from water matrices: A state-of-art review

Journal of Water Process Engineering, Journal Year: 2025, Volume and Issue: 70, P. 106901 - 106901

Published: Jan. 14, 2025

Language: Английский

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Occurrence and seasonal variability of analgesic and anti-inflammatory drugs (AAIDs) in the influent and effluent from WWTP in Słupsk (Poland)

Ecohydrology & Hydrobiology, Journal Year: 2025, Volume and Issue: unknown, P. 100642 - 100642

Published: Jan. 1, 2025

Language: Английский

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A Review on Pharmaceuticals and Personal Care Products Residues in the Aquatic Environment and Possibilities for Their Remediation

Sustainability, Journal Year: 2023, Volume and Issue: 16(1), P. 169 - 169

Published: Dec. 23, 2023

Pharmaceuticals and Personal Care Products (PPCPs) are pollutants known as organic micropollutants. PPCPs belong to a group of compounds with proven biological activity used in medicine, veterinary medicine maintain hygiene daily life. Their presence the environment, even trace concentrations, can have negative effects on living organisms, including humans. Especially relevant residues pharmaceuticals such hormonal drugs antibiotics. PPCPs’ environment is caused by improper production, usage disposal medicines. their may be introduced into various parts wastewater, water soil. Therefore, wastewater containing PPCPs, active metabolites firstly goes treatment plant (WWTP). However, some these also present sewage sludge. This article reviews methods technologies remediation residues. Among them, physical, chemical methods, well compilation techniques, identified. Nowadays, time energy crisis, it important emphasize that applied not only effective, but been characterized low consumption or allow for generation could needs plant.

Language: Английский

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Ecotoxicological mixture risk assessment of 35 pharmaceuticals in wastewater effluents following post-treatment with ozone and/or granulated activated carbon

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 906, P. 167440 - 167440

Published: Sept. 28, 2023

Reducing the risk posed by mixtures of pharmaceuticals is a goal current initiatives such as European Green Deal to reduce anthropological environmental impacts. Wastewater effluent typically contains large numbers active pharmaceutical ingredients (APIs). For some APIs, existing technology conventional activated sludge (CAS) wastewater treatment plants (WWTPs) have removal rates below 20 %, thus WWTP discharges are adding toxic burden receiving waters. We present an assessment 35 APIs in samples from 82 Northern WWTPs using concentration addition model, and identify respective risk-driving APIs. This then compared corresponding mixture Danish Hillerød subjected post-treatment with varying specific ozone doses (0.15-1.05 mgO3/mgDOC) and/or granulated carbon (GAC). All exceeded thresholds at least factor 30, median RQSUM 92.9, highlighting need for substantial dilution recipient Antibiotics, analgesics anti-depressants were among top drivers 99 % average attributable azithromycin, diclofenac, venlafaxine, clarithromycin mycophenolic acid. Effluent was reduced ozonation concentration-dependent manner, decreasing threshold levels 0.83 following 0.65 mgO3/mg DOC. Fresh GAC also effective reducing both alone treatment, 0.04 0.07 respectively. To our knowledge, this first study comparing "conventional" processes additional joint risks demonstrate technologies, efficacy aquatic environment acceptable limits.

Language: Английский

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Occurrence and risk assessment of pharmaceuticals in hospital wastewater in Costa Rica

Chemosphere, Journal Year: 2023, Volume and Issue: 339, P. 139746 - 139746

Published: Aug. 5, 2023

Language: Английский

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