Journal of Pest Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 22, 2024
Metal
phosphides,
particularly
aluminium
phosphide
(AlP)
and
zinc
(Zn3P2),
are
widely
used
in
low-
middle-income
countries
(LMICs)
as
rodenticides
urban
domestic
environments
due
to
their
low
cost
high
toxicity
rodent
pests.
However,
they
also
highly
toxic
humans
with
no
antidote
available
have
been
associated
numerous
fatal
cases
of
intentional
accidental
poisoning.
This
paper
reviews
alternatives
metal
use
for
pest
management
environments,
highlights
case
studies
effective
alternative
approaches,
provides
recommendations
research
policy.
review
identifies
methods
managing
pests
domestic/urban
settings
that
can
replace
phosphides.
These
include
chemical
methods,
i.e.
rodenticides,
non-chemical
e.g.
rodent-proofing,
sanitation
trapping.
because
the
majority
qualify
hazardous
pesticides
acute
human
health
toxicity,
environmental
and/or
bioaccumulation,
simply
selecting
substitute
phosphides
likely
one
set
hazards
others.
Thus,
careful
risk
hazard
assessments
needed
when
considering
substituting
other
chemicals.
Overall,
we
need
move
away
from
current
levels
rodenticide
reliance
towards
more
integrated
ecologically
based
approaches.
Frontiers in Public Health,
Journal Year:
2024,
Volume and Issue:
12
Published: Nov. 5, 2024
Poisoning
caused
by
pesticides
is
widely
recognized
as
a
major
public
health
problem
among
smallholder
farmers
and
rural
communities,
including
in
the
Caribbean.
However,
lack
of
quality
data
impedes
understanding
hampers
development
effective
strategies
for
its
management.
To
better
understand
prevalence
unintentional
acute
pesticide
poisoning
(UAPP)
Trinidad
Tobago
Jamaica
practices
involved,
we
conducted
cross-sectional
survey
197
330
vegetable
Jamaica,
respectively.
The
findings
from
this
study
revealed
high
incidence
self-reported
effects
occupational
exposure,
with
48
16%
respondents,
respectively,
experiencing
symptoms
UAPP
within
previous
12
months.
Furthermore,
substantial
proportion
incidents
were
associated
few
highly
hazardous
(HHPs),
particularly
lambda-cyhalothrin,
acetamiprid,
profenofos
alpha-cypermethrin,
paraquat
lambda-cyhalothrin
Trinidad.
Given
well-documented
adverse
these
chemicals
on
human
health,
results
should
be
significant
concern
to
authorities
This
clearly
indicates
an
urgent
need
improved
regulation
safer
alternatives
use
HHPs,
well
promotion
alternatives.
We
provide
policy
recommendations
identify
HHPs
tropical
production.
Jurnal Ilmiah Pertanian,
Journal Year:
2023,
Volume and Issue:
20(3), P. 219 - 231
Published: Dec. 24, 2023
Amid
escalating
concerns
about
pesticide
residues
in
agricultural
product,
this
study
conducts
a
meticulous
comparative
analysis
of
residue
profiles
locally
grown
rice,
aiming
to
contribute
essential
insights
for
informed
decision-making
agriculture.
The
overarching
problem
addressed
involves
identifying
pesticides
rice
from
conventional
and
sustainable
farming
understanding
their
potential
environmental
health
implications
on
food
safety.
Utilizing
HPLC/MS-MS,
the
research
discerns
notable
absence
over
500
types
cultivated
according
good
practices
(GAP).
Conversely,
fields
deviating
GAP
guidelines
reveals
presence
7
active
ingredients,
with
2
exceeding
globally
established
limits
by
twice
recommended
amount.
Notably,
bifenthrin
tebuconazole,
uncommonly
used
last
one
years,
are
identified.
This
underscores
urgency
adhering
safety
quality
offering
critical
future
research.
It
not
only
contributes
current
knowledge
but
also
emphasizes
global
necessity
safe
safeguard
our
supply.
Ecotoxicology and Environmental Safety,
Journal Year:
2023,
Volume and Issue:
263, P. 115356 - 115356
Published: Aug. 15, 2023
Paraquat
(PQ)
is
an
environmental
poison
that
causes
clinical
symptoms
similar
to
those
of
Parkinson's
disease
(PD)
in
vitro
and
rodents.
It
can
lead
the
activation
microglia
apoptosis
dopaminergic
neurons.
However,
exact
role
mechanism
microglial
PQ-induced
neuronal
degeneration
remain
unknown.
Here,
we
isolated
microglia-derived
exosomes
exposed
with
0
40
μM
PQ,
which
were
subsequently
co-incubated
PQ-exposed
cells
simulate
intercellular
communication.
First,
found
released
from
caused
a
change
cell
vitality
reversed
apoptosis.
RNA
sequencing
data
showed
these
activated
carried
large
amounts
circZNRF1.
Moreover,
bioinformatics
method
was
used
study
underlying
circZNRF1
regulating
PD,
miR-17-5p
predicted
be
its
target.
Second,
increased
Bcl2/Bax
ratio
could
play
anti-apoptotic
role.
Bcl2
downstream
target
miR-17-5p.
Our
results
plays
by
absorbing
binding
after
are
internalized
In
conclusion,
demonstrated
new
communication
between
neurons,
key
protecting
against
through
regulate
biological
process
PD.
These
findings
may
offer
novel
approach
preventing
treating
Toxics,
Journal Year:
2023,
Volume and Issue:
11(10), P. 842 - 842
Published: Oct. 7, 2023
Early-life
exposure
to
environmental
neurotoxicants
is
known
have
lasting
effects
on
organisms.
In
this
study,
we
aim
investigate
the
impacts
of
PQ
during
early
developmental
stages
and
adult
re-challenge
in
aged
mice
non-motor
neurobehavior.
Two
mouse
models,
which
were
exposed
once
life
stage
re-exposure
at
adulthood,
created
explore
long-term
As
results
showed,
early-life
caused
impairment
working
memory
cognitive
ability
male
mice,
but
not
female
exhibiting
a
sex-specific
impairment.
Moreover,
that
re-challenged
with
adulthood
following
also
exhibited
neurobehavioral
disorders.
Notably,
exacerbated
disorders
anxiety
levels
compared
single
different
stages.
Collectively,
can
result
irreversible
impairments
neurobehavior
increase
susceptibility
subsequent
insults
suggesting
greater
sensitivity
rodents
PQ-induced
deficits.
The Lancet Regional Health - Americas,
Journal Year:
2024,
Volume and Issue:
36, P. 100831 - 100831
Published: July 16, 2024
The
suicide
mortality
rate
has
been
increasing
in
Region
of
the
Americas,
despite
decreasing
all
other
World
Health
Organization
(WHO)
regions.
Means
restriction
is
an
effective
evidence-based
intervention
for
prevention.
objective
current
study
was
to
estimate
impact
implementing
national-level
means
policies
(i.e.,
firearm
and
pesticide
restrictions)
on
Americas.
