Applied In Vitro Toxicology, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 13, 2024
Language: Английский
ACS Omega, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 18, 2025
Silver nanoparticles (AgNPs) are widely recognized for their unique optical, electronic, and antibacterial properties, enabling use in biosensing, photonics, electronics, drug delivery, antimicrobial treatments. Green chemistry-based biological synthesis methods offer an eco-friendly alternative to traditional chemical techniques. Among metallic (NPs) metal oxides, those derived from plant extracts exhibit notable medicinal properties. Due exceptional stability low reactivity, AgNPs particularly well-suited various applications. can be synthesized through chemical, physical, or methods, each with distinct benefits challenges. Chemical physical approaches often involve complex purification, reactive reagents, high energy demands, while though slower, provide sustainable solutions. The chosen method strongly influences the stability, size, purity of resulting NPs. This review emphasizes importance selecting appropriate optimize characteristics functionality silver It consolidates research spanning past two decades, including most recent findings 2024. A comprehensive electronic search databases such as PubMed, Scopus, ScienceDirect, Cochrane, Google Scholar was conducted up-to-date overview advances applications nanoparticles.
Language: Английский
Citations
1
BIO Integration, Journal Year: 2024, Volume and Issue: 5(1)
Published: Jan. 1, 2024
Abstract Cancer is a significant disease that poses major threat to human health. Image-guided cancer therapy refers series of medical procedures use imaging technology precisely locate and treat cancer. Combining the dual characteristics images functional nanomaterial (NM) drug carriers, various integrated diagnosis treatment probes have been developed for in vivo dynamic monitoring therapeutic effect evaluation drugs based on imaging. Copper (Cu)-based NMs emerged as valuable products nanotechnology due their unique physicochemical properties, which are influenced by factors, such size, shape, surface properties. In field imaging, Cu-based offer combination desirable characteristics, including fluorescence emission, contrast enhancement, radiolabeling stability. These properties form foundation wide range modalities. addition, can be used carrier diagnostic or synergistic multiple modalities realized doping transition metals into heterostructures. become an important basis imaging-guided with NMs. this review we introduce biocompatible image-guided provide overview promising outcomes biomedical research.
Language: Английский
Citations
5
RSC Advances, Journal Year: 2025, Volume and Issue: 15(11), P. 8480 - 8505
Published: Jan. 1, 2025
Silver nanoparticle-polymer nanocomposites (AgNP-PNCs) represent a transformative advancement in biomedical material science, integrating the potent antimicrobial properties of AgNPs with structural versatility polymer matrices. This synergy enables enhanced infection control, mechanical stability, and controlled drug delivery, making these highly suitable for applications such as wound healing, medical coatings, tissue engineering, biosensors. Recent progress synthesis functionalization has led to greater control over particle morphology, dispersion, optimizing AgNP-PNCs clinical translational applications. However, challenges related cytotoxicity, long-term immune response, scalability persist, necessitating systematic improvements surface functionalization, hybridization strategies, biocompatibility assessments. review critically evaluates latest advancements AgNP-PNC development, focusing on their techniques, regulatory considerations, emerging strategies overcome challenges. Additionally, it discusses preclinical aspects, including commercialization barriers frameworks FDA EMA guidelines, ensuring comprehensive outlook feasibility. By bridging gap between innovation practical application, this investigates potential advancing next-generation materials.
Language: Английский
Citations
0
Journal of Biomaterials Science Polymer Edition, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 22
Published: Nov. 7, 2024
This study aims to prepare, characterize, and evaluate zinc oxide nanoscaffolds (ZnO NSs) as a potential anticancer drug that selectively targets malignant cells while remaining non-toxic normal cells. Electrospun NSs were fabricated loaded with varying concentrations of ZnO nanoparticles (NPs). The uniform morphology the samples was confirmed through Field Emission Scanning Electron Microscope (FESEM) imaging. Elemental composition investigated using Energy Dispersive X-ray spectroscopy (EDX), Fourier Transform Infrared (FTIR), diffraction (XRD) analyses. Biocompatibility cytotoxicity assessed (3-(4.5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay) (MTT) assay flow cytometry. water uptake degradation properties electrospun also examined. Furthermore, cumulative release profile generated assess behavior NSs. prepared demonstrated negligible toxicity toward human dermal Conversely, four used displayed substantial induced apoptosis in various cancer cell lines. observed effects concentration-dependent. Notably, 8% exhibited most significant reduction viability against MCF7 line. findings from this indicate an effective agent, demonstrating pronounced impact. research introduces novel application nanoscaffolds, their capacity for selective activity, particularly breast carcinoma, preserving viability. presents advancement use nanomaterial targeted therapy.
Language: Английский
Citations
0
Applied In Vitro Toxicology, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 13, 2024
Language: Английский
Citations
0