Copper(ii)-based metal–organic framework delivery of calcium ascorbate for enhanced chemodynamic therapy via H2O2 self-supply and glutathione depletion DOI
Meng Zhang, Hongjin Xue, Jiaxin Yang

et al.

Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(7), P. 1871 - 1882

Published: Jan. 1, 2024

A Cu/ZIF-8/Vc-Ca/HA nanosystem synchronously releases Fenton catalytic Cu 2+ and Vc-Ca to achieve improved chemodynamic therapy via H 2 O self-supply GSH depletion.

Language: Английский

Nanozyme‐Enhanced Electrochemical Biosensors: Mechanisms and Applications DOI
Zhongwei Yang, Jiawei Guo, Longwei Wang

et al.

Small, Journal Year: 2023, Volume and Issue: 20(14)

Published: Nov. 20, 2023

Abstract Nanozymes, as innovative materials, have demonstrated remarkable potential in the field of electrochemical biosensors. This article provides an overview mechanisms and extensive practical applications nanozymes First, definition characteristics are introduced, emphasizing their significant role constructing efficient sensors. Subsequently, several common categories nanozyme materials delved into, including metal‐based, carbon‐based, metal‐organic framework, layered double hydroxide nanostructures, discussing Regarding mechanisms, two key roles particularly focused biosensors: selective enhancement signal amplification, which crucially support sensor performance. In terms applications, widespread use nanozyme‐based biosensors showcased various domains. From detecting biomolecules, pollutants, nucleic acids, proteins, to cells, providing robust means for high‐sensitivity detection. Furthermore, insights into future development is provided, encompassing improvements optimizations design integration, expansion application fields through interdisciplinary collaboration. conclusion, this systematically presents biosensors, offering valuable references prospects research field.

Language: Английский

Citations

63

Electrochemical sensing mechanisms of neonicotinoid pesticides and recent progress in utilizing functional materials for electrochemical detection platforms DOI
Longhua Ding, Jiawei Guo, Shu Chen

et al.

Talanta, Journal Year: 2024, Volume and Issue: 273, P. 125937 - 125937

Published: March 16, 2024

Language: Английский

Citations

30

Oxidase mimicking nanozyme: Classification, catalytic mechanisms and sensing applications DOI

Ziting Lin,

Jinlong Yuan,

Lingxi Niu

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 520, P. 216166 - 216166

Published: Aug. 22, 2024

Language: Английский

Citations

28

Recent Development of Copper‐Based Nanozymes for Biomedical Applications DOI
Xin Yu, Yawen Wang, Jian Zhang

et al.

Advanced Healthcare Materials, Journal Year: 2023, Volume and Issue: 13(1)

Published: Sept. 24, 2023

Copper (Cu), an indispensable trace element within the human body, serving as intrinsic constituent of numerous natural enzymes, carrying out vital biological functions. Furthermore, nanomaterials exhibiting enzyme-mimicking properties, commonly known nanozymes, possess distinct advantages over their enzyme counterparts, including cost-effectiveness, enhanced stability, and adjustable performance. These advantageous attributes have captivated attention researchers, inspiring them to devise various Cu-based nanomaterials, such copper oxide, Cu metal-organic framework, CuS, explore potential in enzymatic catalysis. This comprehensive review encapsulates most recent advancements illuminating applications realm biochemistry. Initially, it is delved into emulation typical types achieved by nanomaterials. Subsequently, latest breakthroughs concerning nanozymes biochemical sensing, bacterial inhibition, cancer therapy, neurodegenerative diseases treatment discussed. Within this segment, also explored modulation nanozyme activity. Finally, a visionary outlook for future development presented.

Language: Английский

Citations

42

A flexible electrochemical sensor for paracetamol based on porous honeycomb-like NiCo-MOF nanosheets DOI
Xiuli Liu, Jiawei Guo, Yawen Wang

et al.

Rare Metals, Journal Year: 2023, Volume and Issue: 42(10), P. 3311 - 3317

Published: Aug. 27, 2023

Language: Английский

Citations

40

Hierarchical porous 3D Ni3N-CoN/NC heterojunction nanosheets with nitrogen vacancies for high-performance flexible supercapacitor DOI
Jiawei Guo, Hongbo Zhao, Zhongwei Yang

et al.

Nano Energy, Journal Year: 2023, Volume and Issue: 116, P. 108763 - 108763

Published: Aug. 8, 2023

Language: Английский

Citations

39

Nanozyme engineering in structurally explicit framework: Design mechanisms and biosensing applications DOI
Yanbin Xu,

Anlian Huang,

Wei Yi

et al.

Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 500, P. 215517 - 215517

Published: Nov. 6, 2023

Language: Английский

Citations

38

Advances in the application of metal–organic framework nanozymes in colorimetric sensing of heavy metal ions DOI
Li Zhang,

Xiaoya Bi,

Xiaohong Liu

et al.

Nanoscale, Journal Year: 2023, Volume and Issue: 15(31), P. 12853 - 12867

Published: Jan. 1, 2023

Nanozymes, which can be defined as nanomaterials with excellent catalytic function, are well known to the scientific community due their distinct merits, such low cost and high stability, render them preferable natural enzymes. As porous organic-inorganic coordination materials, metal-organic frameworks (MOFs) possess a large number of active sites thus effectively mimic properties Recently, MOF-based nanozymes have also exhibited good application potential for analysis heavy metal ions. In comparison traditional detection methods ions, nanozyme-based colorimetric sensing permits intuitive visual by using relatively simple instruments, facilitating rapid on-site screening. this minireview, preparation different nanozyme activity types briefly described, peroxidase-like oxidase-like, relevant mechanisms elaborated. Based on this, response turn-off, turn-on, turn-off-on, discussed. addition, applications ions summarized. Finally, current research status future development direction

Language: Английский

Citations

27

Copper regulation of PtRhRuCu nanozyme targeted boosting peroxidase-like activity for ultrasensitive smartphone-assisted colorimetric sensing of glucose DOI

Xinpeng Zhi,

Qi Yang, Xinghao Zhang

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 445, P. 138788 - 138788

Published: Feb. 17, 2024

Language: Английский

Citations

16

Solid-Phase Electrochemiluminescence Enzyme Electrodes Based on Nanocage Arrays for Highly Sensitive Detection of Cholesterol DOI Creative Commons

Xinying Ma,

Zhe Zhang, Yanyan Zheng

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(8), P. 403 - 403

Published: Aug. 21, 2024

The convenient and sensitive detection of metabolites is great significance for understanding human health status drug development. Solid-phase electrochemiluminescence (ECL) enzyme electrodes show potential in metabolite based on the enzyme-catalyzed reaction product hydrogen peroxide (H2O2). Herein, a solid-phase ECL sensor was fabricated confined emitter an immobilized using electrostatic nanocage array, constructing platform cholesterol. cage nanochannel consists bipolar bilayer vertically aligned mesoporous silica film (bp-VMSF). upper layer bp-VMSF amino-modified, positively charged VMSF (p-VMSF), lower negatively (n-VMSF). most commonly used probe tris(bipyridine)ruthenium(II) (Ru(bpy)32+) fixed n-VMSF by adsorption from repulsion p-VMSF, generating significantly enhanced stable signals. successful preparation characterized scanning electron microscopy (SEM) electrochemical methods. After amino groups outer surface were derivatized with aldehyde, cholesterol oxidase (ChOx) molecules covalently immobilized. construction electrode cyclic voltammetry (CV) impedance spectroscopy (EIS). When corresponding substrate, cholesterol, present solution, signal Ru(bpy)32+ quenched H2O2, enabling high-sensitivity linear range detecting 0.05 mM to 5.0 mM, limit (LOD) 1.5 μM.

Language: Английский

Citations

14