Feeding the future: A new potential nutritional impact of lactiplantibacillus plantarum and its promising interventions in future for poultry industry

Poultry Science, Journal Year: 2025, Volume and Issue: unknown, P. 105130 - 105130

Published: April 1, 2025

The increasing demand for sustainable and efficient chicken production has intensified the interest in functional feed additives such as probiotics. Lactiplantibacillus plantarum (formerly known Lactobacillus plantarum) is an important probiotic bacterium that become essential component poultry nutrition owing to its diverse advantages. This improves gut health by regulating intestinal microbiota, food absorption, strengthening immune system. It also alleviates detrimental impacts of pathogenic bacteria, thereby reducing reliance on antibiotics promoting antibiotic-free production. Additionally, enhances growth performance, conversion efficiency, total flock productivity. Adding helps microbiota encouraging good bacterial communities (e.g., Eubacterium, Faecalibacterium, Ligilactobacillus, Limosilactobacillus, Blautia Clostridium). leads increased chickens maintain balance their flora. been extensively investigated a potential additive replace in-feed antibiotics. Published literature have revealed dietary improved broilers improving bacteria metabolism nutrients gut. study explores incorporation into diets importance healthy will encourage scientists investigate further before encapsulation. Innovations plantarum, including intestine colonization methods novel strategies improve colonization, transform industry. Rapid development tools techniques (microencapsulated, nanotechnology, metagenomics, transcriptome L. could help cover research application shortages.

Language: Английский

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Editorial: The role of gut microbiota in animal gastrointestinal diseases

Frontiers in Cellular and Infection Microbiology, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 29, 2025

the gut microbiota is closely associated with host's nutrient metabolism, digestion, absorption, and maturation of immune system (Ansaldo et al.,2019;Wang al.,2024). Furthermore, research has highlighted its vigorous contributions to intestinal barrier integrity, bone development, epithelial cell differentiation, disease prevention management (Yuan As an essential biochemical convertor, can utilize food nutrients ingested by host produce metabolites that benefit health, including short-chain fatty acids, antimicrobial peptides, vitamins (Liu al.,2019;Marra al.,2021). These are critical for maintaining health supportvarious physiological functions. However, sensitive alterations induced a range external factors. For instance, age, gender, species important internal factors influence composition structure (Lee al.,2023). Additionally, such as heavy metals, antibiotics, pesticides markedly disrupt composition, leading dysbiosis (Kaur al.,2023;Li Research indicated development various diseases, particularly disorders diarrhea, colitis, colorectal cancer (Wang Moreover, in intestine, releases from certain pathogens, lipopolysaccharides which breach jeopardize contributing onset diseases (Shen Therefore, stability health. Given significant role gastrointestinal increasing number studies dedicated exploring potential relationships between tract. This unique electronic collection includes some articles covering all above aspects.Rumen acidosis one most prevalent affecting beef cattle, significantly threatening their growth performance, posing substantial risk cattle industry. Despite importance, relatively few examine relationship rumen microbiota. Wu al. ( 2024) conducted high-throughput sequencing study involving 8 healthy calves diagnosed acidosis, revealing induce diversity calves. Specifically, was found affect 70 bacterial genera, 47 exhibiting increased abundance 23 showing decreased abundance. Notably, levels beneficial bacteria, Prevotella, Succinivibrio, Succinivibrionaceae, significantly. changes may serve driving acidosis.Yaks indigenous breed inhabiting Qinghai-Tibet Plateau, strong adaptability high-altitude hypoxic environment. yaks vital means transportation residents Plateau provide milk, meat products, leather. susceptible diarrhea caused Escherichia coli, lead economic losses issues. Diarrhea primary causes reduced productivity mortality ruminants considered major factor impeding animal husbandry countries. Early surveys affects nearly ruminants, newborn goats, sheep, yaks, whose tracts not yet fully developed, resulting death approximately half these animals. The contains diverse array microorganisms, lactic acid bifidobacteria, lactococci. probiotics have demonstrated managing ruminants. Zhang (2024) bacteria reduce translocation rate pathogens enhance barrier, thereby alleviating E. coli yaks. Consequently, promising therapeutic option treating infections yaks.Factors transportation, vaccinations, heat stress negatively impact calves, immunity well morbidity mortality. plays crucial resistance, maturation, metabolism. digestion feed conversion rates. enhancing growth. Yang investigated effects supplementation Shen Qi Bu Powder (SQBQP) on serum biochemistry, antioxidants, flora, metabolism results SQBQP enhanced antioxidant capacity, digestive enzyme contents improved demonstrates light ongoing demands antibiotic use, Chinese veterinary compounds aimed at improving growth.In recent years, advancement science technology, coupled faster turnover led explosive industrial production, people's quality life. portion metal products remains ineffectively recyclable, serious threats surrounding environment both animals plants. metals accumulate plants subsequently transfer other humans through chain, presenting considerable public safety. intestine serves pathway enter host, indicating inevitably affected metals. discovered zinc kidney damage, function, cause imbalances piglets. this microbiota, central 'gut-kidney' axis, play promoting zinc-induced nephrotoxicity. hesperidin been shown mitigate adverse piglet modulating

Language: Английский

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Integrated microbiome and metabolomics analysis reveals the alleviating effect of Pediococcus acidilactici on colitis

Frontiers in Veterinary Science, Journal Year: 2025, Volume and Issue: 12

Published: Feb. 26, 2025

Colitis is a complicated disease caused by multiple factors, seriously threatening the host health and development of animal husbandry. Probiotics have been demonstrate to participate in active regulation gastrointestinal disease, gut microbiota metabolism, but research on efficacy Pediococcus acidilactici isolated from dogs alleviating colitis remains scarce. Here, we aimed investigate ameliorative effects induced LPS its underlying molecular mechanisms. For this purpose, collected colon contents 15 mice for amplicon sequencing metabolic analysis. Results showed that could relieve damage cytokine disorder colitis. Microbiome analysis cause significant decrease microbial diversity abundance, administration restore index control level. Metabolomics 8 pathways 5 (spermine, L-Arginine, 15-Deoxy-Delta12,14-PGJ2, prostaglandin J2, 15(S)-HETE) metabolites may be involved alleviation acidilactici. In summary, these findings demonstrated positive effect metabolism one mechanisms alleviate Additionally, study also conveyed vital message serve as promising candidate ameliorate

Language: Английский

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Effect of Bacillus subtilis isolated from yaks on D-galactose-induced oxidative stress and hepatic damage in mice

Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 16

Published: March 5, 2025

Acute hepatic injury is a severe condition that always accompanied by oxidative stress and inflammation, seriously threatening the health of host. Probiotics have been shown to be involved in regulation antioxidant system gut microbiota activity, but studies on effects yak derived Bacillus subtilis (B. subtilis) acute liver remain scarce. Here, we aim explore ameliorative B. isolated from yaks caused D-galactose, as well underlying processes. Results indicated administration, particularly BS3, significantly mitigated damage induced D-galactose mice evidenced ameliorating tissue decreasing ALT (p < 0.05) AST levels. Additionally, intervention was demonstrated enhance D-galactose-exposed mice, manifested increased T-AOC SOD, alongside decrease MDA levels 0.05). Meanwhile, could effectively mitigate via modulating Keap1/Nrf2 signaling pathway. Importantly, exhibited pronounced protective effect against D-galactose-induced intestinal barrier dysfunction through improving tight junction proteins. The results suggest BS3 alters abundance some flora such Firmicutes phylum Oscillibacter Lachnospiraceae_NK4A136 genera, which affects composition reverses microbial richness index mice. In summary, these findings serve promising candidate ameliorate injury. positive mucosal may one its mechanisms alleviate

Language: Английский

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Oral Supplementation with Lactic Acid Bacteria Improve the Intestinal Epithelial Barrier and Gut Microbiota of Broiler Chicks to Alleviate Salmonella Enteritidis Infection

Poultry Science, Journal Year: 2024, Volume and Issue: 103(12), P. 104385 - 104385

Published: Oct. 9, 2024

Lactic acid bacteria (LAB) play a key role in regulating the balance of gut microbiota and serve as suitable alternative to antibiotics. This study aims evaluate characteristics 2 LAB isolates Lactiplantibacillus plantarum Lp71 (L. Lp71) Enterococcus faecium Ef72 (E. Ef72), their roles alleviating Salmonella Enteritidis infection. Sixty 1-day-old chicks were randomly divided into 4 groups which treated with or without L. E. mixture for 21 d, then intestinal samples collected analysis, pathological immunohistochemical analysis at 24 h post infection on 22nd d. The results showed that had ability anti-acid anti-bile salt. damaged epithelial barrier reduced expression level tight junction proteins (ZO-1, Claudin-1, Occludin). Oral supplementation could alleviated damages by cause abnormal Akkermansia muciniphila proliferation decrease diversity cecal chicks. These conditions have further led reduce health index (GMHI), improve microbial dysbiosis (MDI). Moreover, oral effectively prevent aforementioned outcomes increase abundance proportions several functions metabolic pathways such transcription signal transduction mechanisms. In summary, be probiotics candidates used damage from enteric pathogens broiler

Language: Английский

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