Clinical Nutrition, Journal Year: 2024, Volume and Issue: 43(7), P. 1736 - 1746
Published: May 29, 2024
Early identification of people at risk cancer-related malnutrition, low muscle mass (LMM) and sarcopenia is crucial to mitigate the impact adverse outcomes. This study investigated factors associated with LMM, malnutrition (probable-) whether these varied in or without a history cancer.
Language: Английский
Current Osteoporosis Reports, Journal Year: 2023, Volume and Issue: 21(2), P. 205 - 215
Published: March 28, 2023
This review identifies exercise-based recommendations to prevent and manage frailty fragility fractures from current clinical practice guidelines. We also critically assess recently published literature in relation exercise interventions mitigate fractures.
Language: Английский
Citations
35
Annals of Geriatric Medicine and Research, Journal Year: 2022, Volume and Issue: 26(4), P. 289 - 295
Published: Dec. 12, 2022
Frailty is an age-related clinical state associated with deterioration across multiple physiological systems and a leading cause of morbidity mortality later in life. To understand how frailty develops what causes its progression, longitudinal data repeated measurements are required. This review summarizes evidence from studies on trajectories, transitions, trends. We identified several consistent findings: increases aging dynamic condition, more recent generations older adults have higher levels. These findings both public health relevance, including the provision healthcare aged care services coming years. Further required, particularly those conducted low- middle-income countries investigating factors changes frailty. The latter may help develop better-targeted interventions to reverse or slow progression
Language: Английский
Citations
29
JNCI Monographs, Journal Year: 2023, Volume and Issue: 2023(61), P. 56 - 67
Published: May 4, 2023
Abstract Body composition assessment (ie, the measurement of muscle and adiposity) impacts several cancer-related outcomes including treatment-related toxicities, treatment responses, complications, prognosis. Traditional modalities for body include mass index, circumference, skinfold thickness, bioelectrical impedance analysis; advanced imaging dual energy x-ray absorptiometry, computerized tomography, magnetic resonance imaging, positron emission tomography. Each modality has its advantages disadvantages, thus requiring an individualized approach in identifying most appropriate measure specific clinical or research situations. Advancements approaches have led to abundance available data, however, lack standardized thresholds classification abnormal adiposity been a barrier adopting these measurements widely care. In this review, we discuss different detail provide guidance on their unique opportunities challenges.
Language: Английский
Citations
19
Calcified Tissue International, Journal Year: 2023, Volume and Issue: 114(1), P. 74 - 81
Published: Dec. 3, 2023
Language: Английский
Citations
14
Clinical Interventions in Aging, Journal Year: 2023, Volume and Issue: Volume 18, P. 809 - 825
Published: May 1, 2023
Purpose: Pre-frailty and frailty in older adults are associated with poor health outcomes increase health-care costs, further worsening during hospitalization. This study aimed to examine the effect of an individualized hospital home, exercise-nutrition self-managed intervention for pre-frail frail hospitalized adults. Patients Methods: Older admitted acute medical unit a tertiary South Australia who were or recruited from September 2020 June 2021, randomized either control group followed up at 3 6 months. The outcome variables program adherence, status by Edmonton Frail Scale (EFS) score, lower extremity physical function, handgrip strength, nutritional status, cognition, mood, health-related quality life, risk functional decline, unplanned readmissions. Results: Participants 79.2 ± 6.6 years old, 63% female, mostly (67%), EFS 8.6± 1.9. Adherence inpatient home visits/telehealth high (91± 13% 92± 21%, respectively). Intention-to-treat analysis using linear regression models showed that participants had significantly greater reduction (− 3.0; 95% CI: − 4.8 3.0) months 2.5; 3.8 1.0, P < 0.001 both) compared group; particularly performance component. There also improvements overall Short Physical Performance Battery score (4.0; 1.3 6.6) (3.9; 1.0 6.9, 0.05 both), mini-mental state examination (2.6; 0.3– 4.8, =0.029) strength (3.7; 0.2– 7.1, =0.039) Geriatric Depression Scale, 2.2; 4.1 0.30, =0.026) as control. Conclusion: provided evidence acceptability patient may benefit alleviate pre-frailty hospitalised Keywords: frailty, self-management, exercise, nutrition therapy
Language: Английский
Citations
13
Archives of Gerontology and Geriatrics, Journal Year: 2023, Volume and Issue: 117, P. 105275 - 105275
Published: Nov. 12, 2023
Language: Английский
Citations
13
Journal of Geriatric Physical Therapy, Journal Year: 2023, Volume and Issue: 47(2), P. 67 - 76
Published: Feb. 24, 2023
Background and Purpose: Despite being associated with serious adverse outcomes, such as mortality, sarcopenia remains largely undiagnosed in older individuals. This study aimed to assess the awareness, practices, barriers enablers clinical implementation of diagnosis treatment among geriatric rehabilitation health care professionals Netherlands. Methods: As part EMPOWER-GR, a cross-sectional survey working Netherlands was undertaken between September 23, 2020, January 28, 2021. Professionals were recruited via provider, professional associations, networks research team, social media. Descriptive statistics used outcomes. Results Discussion: Of 501 professionals, 12.2% physicians, 23.0% physical therapist/occupational therapists, 30.3% dietitians, 19.6% nurses, 11.0% assistants. The concept known by 83.8% participants, 92.5% correctly identified low muscle mass strength (and performance), 73.8% very important management adults admitted for rehabilitation. Although 26.2% 18.9% participants reported screening diagnosing sarcopenia, respectively, their current practice, only 3.0% adequately (revised) definition European Working Group on Sarcopenia Older People. When has been diagnosed, 65.0% initiating consisting resistance exercise training (78.7%), food fortification/high-energy or protein diet (85.4%), oral nutritional supplements (70.4%). Most lack knowledge, access tools, equipment time, while protocol implementation, training, clear responsibilities. Conclusions: awareness is high Netherlands, but adequate almost nonexistent which hampers interventions. Better responsibilities, tools protocols, well prioritization, are needed be diagnosed treated
Language: Английский
Citations
11
Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11
Published: June 20, 2024
Background and Aims Physical performance is a major contributor of mobility independence during older life. Despite progressive decline in musculoskeletal function starts from middle age, several factors acting the life-course can negatively influence functional capacities. Lifestyle interventions incorporating nutrition physical exercise help maximizing muscle capacities early life as well preserving them later Among various dietary compounds, omega-3 polyunsaturated fatty acids (PUFAs) are gaining growing attention for their potential effects on membrane composition function. Indeed, pathways enhanced, such an attenuation pro-inflammatory oxidative stress, mitochondrial function, activation mammalian target rapamycin (mTOR) signaling reduction insulin resistance. Methods We performed narrative review to explore existing literature relationship between PUFAs across life-course. Results Growing evidence randomized controlled trials (RCTs) suggests beneficial including parameters mid On other hand, despite direct association not available literature, some mechanisms by which may contribute improved adult could be hypothesized. Conclusion Omega-3 positive effect parameters. The integration measures future studies would great interest whether starting extending throughout lifespan. However, larger high-quality RCTs needed fully elucidate supplementation mass
Language: Английский
Citations
4
Nutrition Journal, Journal Year: 2025, Volume and Issue: 24(1)
Published: Jan. 16, 2025
Dysgeusia is a distortion of the sense taste whose prevalence and relationship with nutritional status in Metabolic dysfunction-associated Steatotic Liver Disease (MASLD)-related advanced chronic liver disease (ACLD) have never been systematically explored. 200 MASLD patients [60 ≤ F3 fibrosis, 70 compensated ACLD (cACLD), decompensated (dACLD)] were enrolled. At baseline, Child–Pugh (CP) score was determined. Dietary habits, body composition, frailty evaluated. The European Working Group (EWGSOP2) criteria defined sarcopenia. assessed by Dysgeusia-Total-Score (DTS). A visual analog scale identified appetite impairment (VASAI). During 6-month follow-up, liver-related decompensation events (LRDEs) recorded. dysgeusia increased progression, appearing significantly higher compared (65.7% vs 5%, p:0.003), as well dACLD to cACLD (58.5 7.1% p < 0.0001). On 41 presenting dysgeusia, 37 (90.2%) showed significant levels. In dACLD, CP positively correlated both DTS (R:0.742) VASAI (R:0.704), directly (R:0.765) (all Compared without dysgeusia-affected presented lower daily protein intake (g/kg/die) (1.55 ± 0.192 1.34 0.15, Sarcopenia (70.7 41.3%) (69.29 37.9%) more prevalent individuals (both These risk LRDEs occurrence during follow-up [HR:2.205; C.I. 95%:1.186–4.099; p:0.01]. Logistic regression analysis revealed (aOR: 3.32), (aOR:1.32), sarcopenia 3.75), (aOR:3.03) associated this outcome appears predominant MASLD-dACLD and, via impairment, close malnutrition, sarcopenia, frailty, negatively influencing patients' outcomes.
Language: Английский
Citations
0
BMC Geriatrics, Journal Year: 2025, Volume and Issue: 25(1)
Published: Jan. 22, 2025
The Simpler Modified Fried Frailty Scale (SMFFS) has recently been developed from the original scale to ease its use in clinical practice, by transforming items requiring measurements into self-reported inquiries. Its predictive validity needs be clarified, especially populations with a high prevalence of frailty, such as patients heart failure (HF). Primary aim this study is find out frailty older HF using SMFFS and show concordance other assessment tools. Secondary reveal whether useful predict mortality follow-up. This prospective, follow-up including adults (≥ 65 years) HF. was used assess phenotype presence ≥ 3 accepted frailty. FRAIL scale, Study Osteoporosis Fractures (SOF) index, Edmonton (EFS) were alternatively correlation different scales. Cox-regression analysis performed identify SMFFS-defined could follow-up, adjusting for list characteristics geriatric syndromes. Among 101 HF, 44 (42.8%) female. Mean age 75.8 ± 7.6 63.4% according SMFFS. showed strong In median 759 days, cardiomegaly, increased pulmonary artery pressure (PAP) defined only predictors after adjustments age, falls previous year, undernutrition, probable sarcopenia, functional impairments, quality life [HR (95% CI) 3.88 (1.05–14.3), 1.05 (1.01–1.09), 10.96 (1.07–112.05) (p = 0.027); PAP, respectively]. As screening tool, independently associated two years. recommended guidelines risk stratification seems more effectively integrated routine practice easy practical Further large studies are needed support
Language: Английский
Citations
0