The Microbe, Journal Year: 2025, Volume and Issue: unknown, P. 100391 - 100391
Published: May 1, 2025
Language: Английский
Pathogens, Journal Year: 2025, Volume and Issue: 14(2), P. 126 - 126
Published: Feb. 1, 2025
Fungal infections are a significant global health challenge, causing approximately 3.8 million deaths annually, with immunocompromised populations particularly at risk. Traditional antifungal therapies, including azoles, echinocandins, and polyenes, face limitations due to rising resistance, toxicity, inadequate treatment options. This review explores innovative strategies for preventing managing fungal infections, such as vaccines, peptides, nanotechnology, probiotics, immunotherapy. Vaccines offer promising avenues long-term protection, despite difficulties in their development complexity immune evasion mechanisms. Antifungal peptides provide novel class of agents broad-spectrum activity reduced resistance risk, whilst nanotechnology enables targeted, effective drug delivery systems. Probiotics show potential vulvovaginal candidiasis, by maintaining microbial balance. Immunotherapy leverages system modulation enhance defenses, omics technologies deliver comprehensive insights into biology, paving the way therapeutic vaccine targets. While these approaches hold immense promise, challenges cost, accessibility, translational barriers remain. A coordinated effort among researchers, clinicians, policymakers is critical advancing addressing burden effectively.
Language: Английский
Citations
3
Fungal Diversity, Journal Year: 2025, Volume and Issue: unknown
Published: March 5, 2025
Language: Английский
Citations
3
Circular Economy and Sustainability, Journal Year: 2025, Volume and Issue: unknown
Published: April 10, 2025
Language: Английский
Citations
2
Trends in Ecology & Evolution, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 1, 2024
Fungi are crucial for terrestrial ecosystems, yet the role of fungal diversity in ecosystem functions remains unclear. We synthesize biodiversity and function (BEF) relationships, focusing on plant biomass production, carbon storage, decomposition, pathogen or parasite resistance. The observed BEF relationships these vary strength direction, complicating generalizations. Strong positive generally when multiple addressed simultaneously. Often, community composition outperforms species richness predicting functions. For more comprehensive research, we recommend studying natural communities, considering simultaneous a broader array guilds across spatiotemporal scales, integrating assembly concepts into research. this, propose conceptual framework testable hypotheses.
Language: Английский
Citations
7
eFood, Journal Year: 2025, Volume and Issue: 6(1)
Published: Jan. 20, 2025
ABSTRACT Mushrooms have long been an integral part of human culture and health are valued for their nutritional therapeutic properties. Often referred to as a superfood, mushrooms rich in bioactive compounds that provide range benefits including antioxidant, antimicrobial, anticancer, prebiotic, antidiabetic, anti‐inflammatory effects. This review focussed on the diversity mushrooms, emphasizing medicinal significance, explores secondary metabolites with potential applications nutraceuticals pharmaceuticals. It underscores role vital agents developing value‐added products. An overview compounds, such polysaccharides, peptides, proteins, terpenoids, phenolic identified numerous mushroom species. Additionally, addresses advancements fungal biotechnology, particularly use fungi efficient industrial cell factories, influence food quality sustainability. By critically analyzing recent studies, summarizes diverse roles biomolecules pharmaceutical industries highlights significant contribution modern medicine health‐related fields.
Language: Английский
Citations
1
MycoKeys, Journal Year: 2025, Volume and Issue: 112, P. 103 - 125
Published: Jan. 13, 2025
Saprobic fungi are known for their critical role in decomposition and nutrient cycling. The study of saprobic is equally important, as it helps understanding ecological roles identifying hidden diversity. This focused on Aquilaria , which poorly studied compared to economically important hosts like coffee, tea, rubber. Our rigorous process led the collection two new terrestrial from Guangdong Yunnan provinces China. After extensive phylogenetic analyses detailed comparison morphological characteristics, collections were identified species belonging Pleosporales, Ascomycota. Aquilariomyces maomingensis sp. nov. was isolated sinensis Province, while Mangifericomes aquilariae Province. Full descriptions, photo plates, (maximum likelihood Bayesian inference based LSU, ITS, SSU, tef 1-α, rpb 2 gene combinations) provided, along with a comprehensive list associated spp.
Language: Английский
Citations
0
MycoKeys, Journal Year: 2025, Volume and Issue: 113, P. 101 - 121
Published: Jan. 31, 2025
During an ongoing investigation of fungi associated with ferns in southwestern China, three hyphomycetes were discovered on the dead rachises Angiopterisfokiensis and unidentified fern. Based morphology multi-gene phylogenetic analyses, Arthrobotrysangiopteridis Corynesporaseptata are introduced as new species. is a nematode-trapping fungus characterized by macronematous, mononematous, hyaline conidiophores, conidiogenous cells polyblastic denticles at each node, 0-1-septate, clavate to elongate pyriform, conidia. features pale brown dark integrated, monotretic up 7-distoseptate one true septum, subcylindrical obclavate, Detailed descriptions illustrations these two species provided, along morphological comparisons taxa closely related
Language: Английский
Citations
0
Reference series in phytochemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 36
Published: Jan. 1, 2025
Language: Английский
Citations
0
MycoKeys, Journal Year: 2025, Volume and Issue: 113, P. 237 - 262
Published: Feb. 12, 2025
Four new fungi, viz. Clavulinopsiswumengshanensis (Clavariaceae, Agaricales), Henningsomycesbambusae (Porotheleaceae, Xenasmabisterigmatae, and X.guttulata (Xenasmataceae, Russulales), from Yunnan Province in China, are proposed, based on a combination of morphological features molecular evidence. Phylogenetic analyses were conducted using combined dataset internal transcribed space nuclear ribosomal RNA large subunit sequences. The ITS+LSU analysis showed that sp. nov. groups with C.aurantiocinnabarina, forms sister group H.candidus, Xenasmabisterigmatae is clustered X.rimicola, X.pruinosum. morphology multi-gene phylogenetic confirmed the placement four taxa. distinguished by buff-yellow to straw-yellow basidiomata, clavate subcylindrical basidia sterigmata, subglobose basidiospores several guttules (7-8.5 × 6-7.5 µm); characterized white cream basidiomata short cylindric tubular colonies, cylindrical two sterigmata globose (6.5-8.5 6.5-8.5 can be its membranaceous ash-grey ellipsoid (10-12.5 8-10.5 narrowly (7-9 5.5-7.5 µm).
Language: Английский
Citations
0
Plant Cell Reports, Journal Year: 2025, Volume and Issue: 44(3)
Published: Feb. 13, 2025
Language: Английский
Citations
0