Molecules,
Journal Year:
2023,
Volume and Issue:
28(15), P. 5931 - 5931
Published: Aug. 7, 2023
Diffusion
is
one
of
the
key
nature
processes
which
plays
an
important
role
in
respiration,
digestion,
and
nutrient
transport
cells.
In
this
regard,
present
article
aims
to
review
various
diffusion
approaches
used
fabricate
different
functional
materials
based
on
hydrogels,
unique
examples
that
control
diffusion.
They
have
found
applications
fields
such
as
drug
encapsulation
delivery,
delivery
agriculture,
developing
for
regenerative
medicine,
creating
stimuli-responsive
soft
robotics
microrobotics.
addition,
mechanisms
release
kinetics
tools
material
design
are
discussed.
Pharmaceutics,
Journal Year:
2025,
Volume and Issue:
17(1), P. 136 - 136
Published: Jan. 19, 2025
Nanosuspensions
(NS),
with
their
submicron
particle
sizes
and
unique
physicochemical
properties,
provide
a
versatile
solution
for
enhancing
the
administration
of
medications
that
are
not
highly
soluble
in
water
or
lipids.
This
review
highlights
recent
advancements,
future
prospects,
challenges
NS-based
drug
delivery,
particularly
oral,
ocular,
transdermal,
pulmonary,
parenteral
routes.
The
conversion
oral
NS
into
powders,
pellets,
granules,
tablets,
capsules,
incorporation
film
dosage
forms
to
address
stability
concerns
is
thoroughly
reviewed.
article
summarizes
key
stabilizers,
polymers,
surfactants,
excipients
used
formulations,
along
ongoing
clinical
trials
patents.
Furthermore,
comprehensive
analysis
various
methods
preparation
provided.
also
explores
vitro
vivo
characterization
techniques,
as
well
scale-down
technologies
bottom-up
preparation.
Selected
examples
commercial
products
discussed.
Rapid
advances
field
could
resolve
issues
related
permeability-limited
absorption
hepatic
first-pass
metabolism,
offering
promise
based
on
proteins
peptides.
evolution
novel
stabilizers
essential
overcome
current
limitations
stability,
bioavailability,
targeting
ability,
safety
profile,
which
ultimately
accelerates
application
commercialization.
Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology,
Journal Year:
2020,
Volume and Issue:
12(6)
Published: May 22, 2020
Abstract
X‐ray
imaging
is
the
most
widely
used
diagnostic
method
in
modern
medicine
and
several
advanced
forms
of
this
technology
have
recently
emerged.
Iodinated
molecules
barium
sulfate
suspensions
are
clinically
approved
contrast
agents
used.
However,
these
existing
provide
limited
information,
suboptimal
for
new
techniques
developing
safety
concerns.
Thus,
over
past
15
years,
there
has
been
a
rapid
growth
development
nanoparticles
as
agents.
Nanoparticles
desirable
features
such
high
payloads,
potential
long
circulation
times,
tunable
physicochemical
properties.
also
range
biomedical
applications
disease
treatment,
targeted
imaging,
cell
tracking.
In
review,
we
discuss
principles
behind
generation
introduce
types
modalities,
well
elements
chemical
compositions
that
suitable
novel
agent
development.
We
focus
on
progress
nanoparticle
developed
to
be
renally
clearable,
circulating,
theranostic,
targeted,
or
feature
conjunction
with
newly
multi‐energy
computed
tomography
mammographic
technologies.
Finally,
offer
perspectives
current
limitations
emerging
research
topics
expectations
future
field.
This
article
categorized
under:
Diagnostic
Tools
>
vivo
Nanodiagnostics
Imaging
Nanotechnology
Approaches
Biology
Nanoscale
Systems
Journal of drug targeting,
Journal Year:
2020,
Volume and Issue:
29(2), P. 131 - 154
Published: Aug. 20, 2020
Mesoporous
silica
nanoparticles
(MSNPs)
are
a
particular
example
of
innovative
nanomaterials
for
the
development
drug
delivery
systems.
MSNPs
have
recently
received
more
attention
biological
and
pharmaceutical
applications
due
to
their
capability
deliver
therapeutic
agents.
Due
unique
structure,
they
can
function
as
an
effective
carrier
agents
mitigate
diseases
progress,
reduce
inflammatory
responses
consequently
improve
cancer
treatment.
The
potency
diagnosis
management
various
has
been
studied.
This
literature
review
will
take
in-depth
look
into
properties
types
(e.g.
shape,
particle
pore
size,
surface
area,
volume
functionalisation),
discuss
characteristics,
in
terms
cellular
uptake,
release.
then
be
discussed
(passive
active
tumour
targeting,
theranostics,
biosensing
immunostimulative),
biocompatibility
safety
issues.
Also,
emerging
trends
expected
future
advancements
this
provided.
